Department of Medical and Health Sciences (IMH)

Artificial heart pump with pulsatile flow

In collaboration with Scandinavian Real Heart we develop the surgical and aenesthesiological technique for implanting an artificial heart in patients with chronic heart failure.

PAINOMICS® Research Group

The aim of the research at Painomics laboratory is to investigate mechanistic markers of nociception and severity of pain, in peripheral and central level in subjects with chronic pain conditions, using omics.

Patients with elective surgery

The project aims to add support to the existing intervention for reducing alcohol consumption, but also increasing physical activity, and weight reduction when necessary.

MoBILE

MoBILE aims to develop, evaluate and implement seven mHealth lifestyle interventions that can be delivered via the healthcare sector to different target groups, including pregnant women, children, young adults, and patients with elective surgery.

Patients in clinical care

This project will focus on self-care disease management and lifestyle behavior change among patients at a medical ward at the county hospital in Motala (Sweden). 

Individuals seeking help at primary healthcare centers

This project aims to develop an mHealth intervention targeting individuals seeking help at primary healthcare centers, for whom a lifestyle change is part of their treatment.

Preschool Children

Childhood obesity remains a significant global health challenge. The preschool age (2-5 years) has been identified as a key period for intervention.

Pregnant woman

Excessive gestational weight gain (GWG) increases the risks for pregnancy complications, postpartum weight retention and offspring obesity.

Young adults

This project will investigate mHealth interventions aimed at promoting improved lifestyle behaviors among high school and university students.

Simulation of Cardiac Blood Flow from CT

Advanced CT creates amazing visualization of the beating heart. However, the complex interactions of blood flow are not fully reflected by these images. This project aims to extract blood flow data from CT images using image-based simulations. 

MRI-based Body Composition Analysis

Metabolic risk related to body-fat accumulation is strongly dependent on fat distribution. This project has developed a method for quantitative assessment of body composition that measures both fat distribution and muscle volume.

Lifestyle Intervention Implementation Research Group

We aim to develop, evaluate and implement behaviour change interventions that can contribute to an improved public health.

Diagnosis and rehabilitation for Whiplash Associated Disorders

Epidemiology and prevention of sports injuries

Our research includes study of injury occurrence and risk factors in sports. We also evaluate the efficacy of injury preventive measures, and their effectiveness, including applicability in different sports and sporting populations.

Dementia-Friendly Community

Better management of musculoskeletal conditions

Our research is focused on reducing the prevalence and burden of musculoskeletal conditions which rank highest in the Global Burden of Disease. This through developing and implementing sustainable high-quality health care.

Natural corollaries and recovery after acute Anterior Cruciate Ligament (ACL) injury – the NACOX cohort study protocol

Anterior cruciate ligament (ACL) injury can result in joint instability, decreased functional performance, reduced physical activity and quality of life, and an increased risk for post-traumatic osteoarthritis.

Physiotherapy - Epidemiology and Prevention

Our research focus is to improve this knowledge of injury and sickness in different populations, especially in sports and work related populations. Epidemiological registering of preventive and health ca interventions is another focus.

Human Movement Science

We improve knowledge of movement system function in healthy as well as individuals with functional impairments due to sicknss of injury. Our reserach utilizes methods for measuring and analyzing the mechanisms required for function and activity.

Mitral Valve Surgery

Mitral valve regurgitation is the most common indication for mitral valve surgery. A repair of the valve results in a more beneficial outcome than a replacement with a prosthesis.

Surgical treatment of atrial fibrillation

Atrial fibrillation is common in patients scheduled for cardiac surgery. We study the impact of different ablation techniques on apoptosis, inflammatory response, atrial function and clinical outcome. 

Evaluation of Aortic valve interventions

In an observational cohort study we follow patients with aortic valve disease from evaluation through the surgery or catheter based intervention to one year follow up.

Wii-project

Playing Wii games can help patients with heart failure to improve their exercise capacity, their daily physical activity quality of life. In this study patients will be randomized into attention control or structured access to a Wii game computer

Twincities Research Group - Social environment and health

The twin cities of Linköping and Norrköping are two equal sized cities in southeast Sweden. They are part of the same county council and have the same structure of health care. How could public health in two so similar cities be so different?

Interprofessional learning in practice

The project has a practice-oriented perspective on learning as embedded in the complexities of practices. An interactive approach comprising ethnographic field studies is applied.

Non-alcoholic fatty liver disease

Our research purposes are to further characterize the natural history of NAFLD, identify factors that influence the progression and to develop and validate diagnostic methods for NAFLD. 

Predictive and personalized medicine for fragile old persons

Physiotherapeutic Diagnostics and Rehabilitation

We conduct clinical research on diagnostic methods and effects of interventions such as therapeutic excercise, manual therapies, pain management modalities as well as pedagogical and behavioral based management strategies.

Learning in virtual health environments

How can IT support learning across different virtual environments (visualisation, virtual patients and simulation) within healthcare education and practice?

Interprofessional learning in simulation-based training for the healthcare professions

The overarching purpose of this project is to develop knowledge on how interprofessional collaboration in healthcare teams could be arranged and trained through simulation-based learning environments.

Vascular Immunology Group

We want to understand why the immune system isn’t balanced in many with coronary heart disease to be able to tailor the treatment of the cause of the disease, rather than the symptoms.

HEART4FLOW

The objective of the HEART4FLOW project is to develop the next generation of methods for the non-invasive quantitative assessment of cardiac diseases and therapies by focusing on 4D blood flow dynamics.

Myocardial Adaptation in Aortic Valve Disease

Aortic valve disease can lead to strain on the left ventricle of the heart and ultimately heart failure. Our research aim for better diagnostics and treatment for these patients. 

Simulation in Health Care - the simulation educator's perspective

We study pedagogical development of instructors in medical simulation over time, with focus on both individual and organisational development.

Vascular Inflammation

The general importance of our research is to clarify pathophysiological concepts in vascular diseases such as abdominal aortic aneurysm and atherosclerosis.

TPMT nomenclature committee

Our aim is to maintain a common, logical nomenclature system for thiopurine methyltransferase (TPMT) alleles in humans.

Skin cancer prevention in primary care

Football Research Group - FRG

Quantitative computed tomography for more accurate radiotherapy

We are developing quantitative image reconstruction methods with dual-energy computed tomography to measure the atomic composition of patient organs before radio thearpy.

Optimizing X-ray imaging procedures

Optimising medical x-ray examination aims to find the settings on the x-ray unit that minimises the patient exposure while maintaining sufficient image quality. 

Retrospective EPR dosimetry

EPR dosimetry for Radiation Therapy

Development of EPR dosimetry system

Sleep Disorders

In my research group, we study brain function in narcolepsy and periodic idiopathic hypersomnia, the Kleine-Levin syndrome, in order to increase the understanding of the patients' symptoms and possibly reduce the time to diagnosis.

Functional brain imaging

In our research group, we use combined fMRI-EEG and mathematical modelling in studies of brain function related to different mental states e.g., sleep, wakefulness, meditation, and pain. 

Mechanistic modelling of brain function

By mathematical modelling, we can test different hypotheses explaining brain function. We apply systems biology approaches to describe the mechanisms behind the neurovascular coupling measured in functional magnetic resonance imaging (fMRI).

Nordic Implementation Interest Group

Nordic Implementation is an interest group of researchers and practitioners, who are exploring and investigating issues concerning implementation of evidence-based practices and quality improvement in health and human services.

Implementation in health care and society

The research program Implementation aims to conduct high-quality interdisciplinary research and education to address important issues concerning implementation and research use in health care and society at large. 

The Cardiodiet Trial

Is a Mediterranean diet with reduced carbohydrate content a better choice than traditional low-fat diet for patients with coronary heart disease?

Reactions and experiences of illness and poor health

An individual’s experience, reaction and management of symptoms, illness and poor health are dependent on the person being viewed from a holistic perspective. 

Development of Nursing Science theory and methodology

To maintain high quality research and nursing care, it is important to develop theories and different concepts that are used in nursing care research. 

Consequences of nursing care and treatment

Quality of life/health-related quality of life, self-care, symptom relief, recovery, functional status and complications are studied.

Prerequisites for health

Human resources for maintaining or recovering health, or accepting an altered life and health situation are studied.

Oncopharmacology

Our research is within the field of Drug research and Onco-pharmacology. Our aim is to identify drugs with new mechanisms of action, and try to develop drug candidates for clinical use.

Importance of pharmacogenetics for individualising chemotherapy

In addition to cellular studies, we study TPMT and the various genetic variants using recombinant protein. We use biophyscial techniques to study the difference in protein stability and drug affinity between TPMT and other genetic varieties.

Phys-Can