Molecular Genetics and Epigenetics, 6 credits (8BKG17)

Molekylär Genetik och Epigenetik, 6 hp

Main field of study

Medical Biology

Level

First cycle

Course type

Programme course

Examiner

Francisca Lottersberger

Course coordinator

Francisca Lottersberger

Director of studies or equivalent

Anna Fahlgren
Course offered for Semester Weeks Language Campus VOF
MGMB2 Bachelor´s Programme in Experimental and Industrial Biomedicine (International admissions round) 1 (Autumn 2020) v202045-202051 English Linköping o
MGMB2 Bachelor´s Programme in Experimental and Industrial Biomedicine (National admissions round) 1 (Autumn 2020) v202045-202051 English Linköping o

Main field of study

Medical Biology

Course level

First cycle

Advancement level

G1X

Course offered for

  • Experimental and Industrial Biomedicine

Entry requirements

General entry requirements for undergraduate studies
and
English corresponding to the level of English in Swedish upper secondary education
(English 6)
And
Chemistry, Mathematics and Biology corresponding to the level in Swedish upper
secondary education (Chemistry 2, Mathematic 4 and Biology 2)
Exemption from Swedish 3

Intended learning outcomes

Knowledge and understanding
On completion of the course, the student shall be able to:

  • Explain how genetic information is structured, inherited, expressed and regulated in eukaryotes
  • Describe what epigenetics is and its role in gene transcription
  • Describe the mechanisms that contribute to genetic variation in humans and explain the relationship between genetic variation and complex diseases
  • Describe the basic ethical problems arising from the medical application of genetics

Skills and abilities
On completion of the course, the student shall be able to:

  • Identify the relevant techniques employed in classical genetic experiments
  • Determine the genetic and/or epigenetic causes and inheritance patterns of familial conditions and evaluate the risk of passing them on
  • Execute basic genetic and epigenetic experiments and present the laboratory results in a scientific report

Judgement ability and approach
On completion of the course, the student shall be able to:

  • Evaluate the advantages, disadvantages and ethical problems that arise in connection with the use of genetic information in healthcare
  • Demonstrate a critical approach to the assessment of basic laboratory experiments
  • Reflect on the use of model organisms in genetic studies

Course content

The course involves the study of basic medical genetics. The course focuses on
molecular genetics, including the structure and function of the human genome,
transcriptional regulation and epigenetics. This molecular knowledge will be
applied in order to understand the genetics of simple and complex diseases, the role
of genetics in modern healthcare and ethical issues arising from its use in
diagnostics and care. In addition, molecular genetic techniques that can be used in
research and medical applications are introduced.
The course covers medical genetics, molecular biology and epigenetics, with links to
pathology and medical ethics.

Teaching and working methods

At the Faculty of Medicine and Health Sciences student centred and problem based
learning make up the foundation of the teaching. The student takes responsibility
for, studies and researches current content of the courses and study programme.
The methods of the course work challenge the students to independently formulate
questions for learning, to seek knowledge and in dialogue with others judge and
evaluate achieved knowledge. Students in the Bachelor’s programme in
Experimental and Industrial Biomedicine work together in groups based on reality
based and course related biomedical issues to apply their knowledges, develop their
own learning, contribute to the fellow students’ learning and to practice
cooperation. Throughout the study programme theory is integrated with practical
modules. The course methods and integration modules stimulates and support the
student’s ability to apply their knowledge and professional competence.
The working methods used in this course are tutorial groups, lectures, seminars and
laboratory exercises.

Examination

Teaching and examination are performed in English.
The forms of examination are one individual written and one individual practical
exam. In addition, active participation in compulsory components is required to
pass the course. Compulsory elements include tutorial groups, seminars, laboratory
sessions with associated reports and assignments.
Resource-demanding examinations, in this syllabus the individual practical
examination, are limited to five attempts. The written examination may be
performed an unlimited number of times by those students who have not achieved a
passing grade.
The examiner can decide to replace the compulsory element with an equivalent task
if there are special reason to do so and if it is possible regarding the character of the
compulsory element.

APPLICATION FOR EXAMINATION / WRITTEN EXAM
Instructions on how to apply for examinations are given prior to the beginning of
each course.

RETAKE EXAMINATION
Point of time for retake examination must normally be announced no later than the
time of the regular examination. The extent of the retake examination must be the
same as the regular examination.

EXAMINATION OF STUDENTS WITH FUNCTIONAL DISABILITY
A student has the right to customized examination in the written exam if the LiU
coordinator for students with functional disabilities has issued this right. If the
coordinator instead has given a recommendation of customized examination or
alternative examination form, the examiner decides whether this could be carried
out in respect to the objectives of the course.

CHANGE OF EXAMINER
A student who has obtained a failing grade twice for a course or a part of a course is,
after request, entitled to be appointed another examiner, unless there are special
reasons to the contrary.

GRADES
The course is graded with the grades Fail or passing grades 3-5, where 3
corresponds to approved, 4 corresponds to approved with credit and 5 corresponds
to approved with distinction. An aggregation of the grades from the individual
written exam and the individual practical exam forms the basis of the final grade of
the course.

Grades

Four-grade scale, LiU, U, 3, 4, 5

Course literature

A literature reference list must be set no later than two months before the course
begins by the programme committee for the Bachelor’s Programme in Experimental
and Industrial Biomedicine. There is no compulsory course literature.

Other information

Planning and implementation of the course is to be based on the wordings in the
course syllabus. A course evaluation is compulsory for each course and should
include how the course is in agreement with the course syllabus. The course
coordinator will analyse the course evaluation and propose appropriate
development of the course. The analysis and proposal will be returned to the
students, the Director of Studies, and as needed to the Education Board, if related to
general development and improvement.
The course is carried out in such a way that knowledge of gender, gender
identity/expression, ethnicity, religion or other belief system, disability, sexual
orientation and age is addressed, highlighted and communicated as part of the
programme.
If the course is cancelled or undergoes major changes, examination is normally
offered under this course syllabus, at a total of three occasions, within/in
connection to the two following semesters, of which one in close proximity to the
first examination.

Department

Medicinska fakulteten
There is no course literature available for this course.
17WE Written examination U, 3, 4, 5 3.5 credits
17PE Practical examination U, 3, 4, 5 1 credits
17CE Compulsory elements U, G 1.5 credits

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