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Stem Cell Engineering, 6 credits
Stamcellsteknik, 6 hp
TVCB13
Main field of study
Engineering BiologyCourse level
Second cycleCourse type
Programme courseExaminer
Stefan KochDirector of studies or equivalent
Kajsa Holmgren PetersonEducation components
Preliminary scheduled hours: 32 hRecommended self-study hours: 128 h
Available for exchange students
YesECV = Elective / Compulsory / Voluntary
| Course offered for | Semester | Period | Timetable module | Language | Campus | ECV | |
|---|---|---|---|---|---|---|---|
| 6CKEB | Chemical Biology (Industrial Biotechnology and Production) | 9 (Autumn 2017) | 2 | 3 | English | Linköping, Valla | E |
| 6CKEB | Chemical Biology (Protein Science and Technology) | 9 (Autumn 2017) | 2 | 3 | English | Linköping, Valla | E |
| 6CTBI | Engineering Biology, M Sc in Engineering (Devices and Materials in Biomedicine) | 9 (Autumn 2017) | 2 | 3 | English | Linköping, Valla | E |
| 6CTBI | Engineering Biology, M Sc in Engineering (Industrial Biotechnology and Production) | 9 (Autumn 2017) | 2 | 3 | English | Linköping, Valla | E |
| 6MPRO | Protein Science, Master's programme (External) | 3 (Autumn 2017) | 2 | 3 | English | Linköping, Valla | E |
Main field of study
Engineering BiologyCourse level
Second cycleAdvancement level
A1XCourse offered for
- Protein Science, Master's programme
- Chemical Biology
- Engineering Biology, M Sc in Engineering
Entry requirements
Note: Admission requirements for non-programme students usually also include admission requirements for the programme and threshold requirements for progression within the programme, or corresponding.
Prerequisites
Three years of previous studies in the area of biotechnology.
Intended learning outcomes
The aim of this course is to provide deeper knowledge in some specific areas of eukaryotic cell biology related to stem cells. By the end of this course the student will be able to:
- Summarize knowledge on models for the regulation of cell growth and cell differentiation.
- Describe different experimental methods used for modifying differentiation and function of cells.
- Discuss relevant ethical issues related to the use of stem cell engineering.
- Independently identify a scientific question of relevance for the topic of the course, search and critically evaluate scientific literature in this field and write a review of the results.
Course content
Growth and differentiation factors. Processes of cell differentiation, apoptosis, regulation and control of the function of stem cells. Epigenetic regulation of gene expression and its role in cell growth and cell function. Principles of aberrant growth control, cancer, stem cell niches, cell editing technologies as well as advantages and disadvantages of these technologies. Reproductive and therapeutic cloning, regenerative medicine and induced pluripotent stem cell technology. Ethical aspects on stem cell technology.
Teaching and working methods
The course applies problem based learning and includes lectures, tutorials, laboratory work and seminars. Tutorials, laboratory work and seminars are compulsory.
Examination
| BAS1 | Study group participation | 2 credits | U, G |
| PRA1 | Individually written report | 2 credits | U, G |
| UPG2 | Seminar on Ethical Issues of Stem Cell Technology | 1 credits | U, G |
| LAB1 | Laboratory Work and Report | 1 credits | U, G |
Clarification BAS1: Active participation in the study group and the following seminars is a prerequisite for the grade ’Pass’.
Grades are given as Pass or Fail.
Grades
Two-grade scale, U, GDepartment
Institutionen för klinisk och experimentell medicinDirector of Studies or equivalent
Kajsa Holmgren PetersonExaminer
Stefan KochEducation components
Preliminary scheduled hours: 32 hRecommended self-study hours: 128 h
Course literature
Additional literature
Books
- Alberts B. et al., (2014) Molecular Biology of the Cell 6th ed Garland Publishing Inc, New York
Please note that the book is not mandatory, but a recommendation.
Articles
| Code | Name | Scope | Grading scale |
|---|---|---|---|
| BAS1 | Study group participation | 2 credits | U, G |
| PRA1 | Individually written report | 2 credits | U, G |
| UPG2 | Seminar on Ethical Issues of Stem Cell Technology | 1 credits | U, G |
| LAB1 | Laboratory Work and Report | 1 credits | U, G |
Clarification BAS1: Active participation in the study group and the following seminars is a prerequisite for the grade ’Pass’.
Grades are given as Pass or Fail.
Regulations (apply to LiU in its entirety)
The university is a government agency whose operations are regulated by legislation and ordinances, which include the Higher Education Act and the Higher Education Ordinance. In addition to legislation and ordinances, operations are subject to several policy documents. The Linköping University rule book collects currently valid decisions of a regulatory nature taken by the university board, the vice-chancellor and faculty/department boards.
LiU’s rule book for education at first-cycle and second-cycle levels is available at http://styrdokument.liu.se/Regelsamling/Innehall/Utbildning_pa_grund-_och_avancerad_niva.
Additional literature
Books
Alberts B. et al., (2014) Molecular Biology of the Cell 6th ed Garland Publishing Inc, New York
Please note that the book is not mandatory, but a recommendation.
Articles
Note: The course matrix might contain more information in Swedish.
I = Introduce, U = Teach, A = Utilize
| I | U | A | Modules | Comment | ||
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| 1. DISCIPLINARY KNOWLEDGE AND REASONING | ||||||
| 1.1 Knowledge of underlying mathematics and science (G1X level) |
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| 1.2 Fundamental engineering knowledge (G1X level) |
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| 1.3 Further knowledge, methods, and tools in one or several subjects in engineering or natural science (G2X level) |
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| 1.4 Advanced knowledge, methods, and tools in one or several subjects in engineering or natural sciences (A1X level) |
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| 1.5 Insight into current research and development work |
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| 2. PERSONAL AND PROFESSIONAL SKILLS AND ATTRIBUTES | ||||||
| 2.1 Analytical reasoning and problem solving |
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| 2.2 Experimentation, investigation, and knowledge discovery |
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| 2.3 System thinking |
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| 2.4 Attitudes, thought, and learning |
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| 2.5 Ethics, equity, and other responsibilities |
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| 3. INTERPERSONAL SKILLS: TEAMWORK AND COMMUNICATION | ||||||
| 3.1 Teamwork |
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| 3.2 Communications |
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| 3.3 Communication in foreign languages |
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| 4. CONCEIVING, DESIGNING, IMPLEMENTING AND OPERATING SYSTEMS IN THE ENTERPRISE, SOCIETAL AND ENVIRONMENTAL CONTEXT | ||||||
| 4.1 External, societal, and environmental context |
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| 4.2 Enterprise and business context |
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| 4.3 Conceiving, system engineering and management |
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| 4.4 Designing |
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| 4.5 Implementing |
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| 4.6 Operating |
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| 5. PLANNING, EXECUTION AND PRESENTATION OF RESEARCH DEVELOPMENT PROJECTS WITH RESPECT TO SCIENTIFIC AND SOCIETAL NEEDS AND REQUIREMENTS | ||||||
| 5.1 Societal conditions, including economic, social, and ecological aspects of sustainable development for knowledge development |
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| 5.2 Economic conditions for knowledge development |
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| 5.3 Identification of needs, structuring and planning of research or development projects |
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| 5.4 Execution of research or development projects |
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| 5.5 Presentation and evaluation of research or development projects |
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