Immunobiology and Immunological Techniques, 6 credits (TVMB17)

Main field of study

Biotechnology, Engineering Biology

Course level

First cycle

Advancement level

G2X

Course offered for

• Engineering Biology, M Sc in Engineering
• Chemical Biology, M Sc in Engineering

Entry requirements

Note: Admission requirements for non-programme students usually also include admission requirements for the programme and threshold requirements for progression within the programme, or corresponding.

Prerequisites

Basic knowledge in biochemistry, cell biology and microbiology, the corresponding rates Biokemi2, Cell Biology and Microbiology or equivalent

Intended learning outcomes

The course will provide theoretical and practical knowledge of the concepts and methods in immune biology and immunology. After the course, participants will be able to

• give an account of how the inflammatory process is initiated, regulated and controlled in the immune system against various infections. This includes knowledge of various inflammatory mediators and inflammatory cells.
• explain how the body's adaptive immunity are regulated and activated in various infections.
• understand how to exploit the immune system to avoid infections. This involves the ability to explain how vaccines and adjuvant function.
• know the various diseases and problems caused by the immune system and could explain the significance of the immune system has in various cases.
• understand the complexity of the different systems (eg complement system, coagulation and other parts) and how they affect each other.
• account for the theory behind and could use some immunological methods.
• have an understanding of how immunological principles used in industry and research.

Course content

Inflammatory mediators (complement system, reactive oxygen metabolites, lysosomal enzymes, cytokines, chemotactic factors), inflammatory cells (phagocytosed cells, interaction with inflammatory mediators); inflammation process, including immune system development and construction (antibodies structure and function, antibody formation, the interaction between antigen-presenting cells, B - cells and Th) cells, various types of vaccines and adjuvants; diseases and problems caused by the immune system (allergic reactions, autoimmune diseases, problems with different types of implants), immunological methods and principles (antigen-antibody reaction, agglutination, precipitation, including immunofluorescensmetoder flow cytometry and Luminex, ELISA).

Teaching and working methods

The course consists of lectures and laboratory practice including a seminar.

Examination

TEN1	Written examination	U, 3, 4, 5	3 credits
LAB1	Laboratory work, report of assignments	U, G	3 credits

Grades

Four-grade scale, LiU, U, 3, 4, 5

Other information

Supplementary courses: Gene technology and molecular genetics, Biotechnology methods, Molecular Virology. 

Department

Institutionen för klinisk och experimentell medicin

Director of Studies or equivalent

Kajsa Holmgren Peterson

Examiner

Jonas Wetterö

Education components

Preliminary scheduled hours: 48 h
Recommended self-study hours: 112 h

Course literature

Janeway’s Immunobiology, 8th ed, Kenneth Murphy (2011), Garland Science.