Johannes Gubat

Publications

2024

Johannes Gubat, Linda Sjöstrand, Karthik Selvaraju, Kübra Telli, Padraig D´arcy (2024) Loss of the proteasomal deubiquitinase USP14 induces growth defects and a senescence phenotype in colorectal cancer cells Scientific Reports, Vol. 14, Article 13037 Continue to DOI

Johannes Gubat (2024) Identifying Essential Deubiquitinase Interactions and Targeting Protein Ubiquitination in Cancer

2022

Johannes Gubat, Karthik Selvaraju, Linda Sjöstrand, Dhananjay Kumar Singh, Maria V Turkina, Bernhard Schmierer, Pierre Sabatier, Roman A. Zubarev, Stig Linder, Pádraig D´arcy (2022) Comprehensive Target Screening and Cellular Profiling of the Cancer-Active Compound b-AP15 Indicate Abrogation of Protein Homeostasis and Organelle Dysfunction as the Primary Mechanism of Action Frontiers in Oncology, Vol. 12, Article 852980 Continue to DOI

2021

Karthik Selvaraju, Kourosh Lotfi, Johannes Gubat, Maria Miquel, Amanda Nilsson, Julia Hill, Lasse D Jensen, Stig Linder, Pádraig D’Arcy (2021) Sensitivity of Acute Myelocytic Leukemia Cells to the Dienone Compound VLX1570 Is Associated with Inhibition of the Ubiquitin-Proteasome System Biomolecules, Vol. 11, Article 1339 Continue to DOI

2020

Arjan Mofers, Karthik Selvaraj, Johannes Gubat, Padraig D´Arcy, Stig Linder (2020) Identification of proteasome inhibitors using analysis of gene expression profiles European Journal of Pharmacology, Vol. 889, Article 173709 Continue to DOI