Division of Clinical Chemistry and Pharmacology (KKF)

The Division of Clinical Chemistry and Pharmacology (KKF) conducts research that includes the subject areas of anesthesiology/intensive care, pharmacology and clinical pharmacology, forensic sciences and clinical chemistry.

The overall goal of the research is to improve diagnosis and treatment by developing new drugs, mapping and using new methods to predict and reduce the risk of serious side effects in e.g. cancer treatment, intensive care and hemostasis disorders. The research also includes projects aimed at solving crimes with the help of advanced analysis and AI, identifying and characterizing new online drugs etc.

The division teaches at basic and advanced level in medical, biomedical and technical education as well as conducts doctoral education.

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Co-workers

Research

blood droplet in red microscope light

Haemostasis Research Group in Linköping

We study regulation of platelet activation and interaction with coagulation from biochemistry and genes to clinical studies on antithrombotic drugs in cardiovascular diseases and how covid-19 causes thrombosis. We also develop new diagnostic methods.

a test tube containing blood.

Genetics and Toxicology in Cancer Chemotherapy and Forensic Sciences

The aim of our research is to identify, validate and implement genetic markers or other biomarkers to predict drug metabolism or drug effects.

A man sits and analyzes a sample in a beaker.

How to solve murders using postmortem metabolomics and artificial intelligence

Successful efforts from this research environment will be implemented into routine case work and will aid police work in providing investigative leads and new tools to expand objective forensic evidence.

News

En person i labbrock som håller i en flaska.

AI provides a more precise time of death

Artificial intelligence can be used to provide a more precise time of death, which can be crucial in e.g. murder investigations. The AI model is trained on so-called metabolites in thousands of blood samples from real deaths.

Man wearing a lab coat holds a test tube containing two green pills.

From lab to legislation – the fight against new online drugs

A new drug on the European market – every week. Professor Henrik Green is using research to help government agencies stop the most dangerous online drugs more quickly.

Henrik Green.

Nerve damage from cancer treatment can be predicted

Many women treated for breast cancer using taxanes, a type of cytostatic drug, often experience side effects in the nervous system. Researchers at LiU have developed a tool that can predict the risk level for each individual.

Organisation