Michelle Nilsson

Postdoc

The electrical signals in our brain are shaped by voltage-gated ion channels. I want to understand the activation and modulation of the voltage-gated ion channels that underlie these signals.

Research

Medium teaser image to the Pantazis Lab at BKV.

Pantazis Laboratory of Cellular Excitability - PaLaCE

In the Pantazis Laboratory of Cellular Excitability - PaLaCE, we employ cutting-edge experimental and computational approaches to understand how the intricate structure of ion channels relates to their function.

News

A subtle genetic change gives new clues about epilepsy

Sometimes, even the alteration of a single nucleotide in a gene can cause serious disease. A recent study sheds light on the molecular biology behind some forms of genetic epilepsy.

A drug from resin to combat epileptic seizures

New molecules, developed by researchers at Linköping University, have promising properties as possible drugs against epilepsy. A study published in the journal Epilepsia shows that several of the molecules have antiseizure effects.

Publications

2024

Michelle Nilsson (2024) Voltage-Sensor Domains of Ion Channels: Physiology, Regulation, and Role in Disease

2022

Michelle Nilsson, Sarah H Lindström, Maki Kaneko, Kaiqian Wang, Teresa Minguez-Viñas, Marina Angelini, Federica Steccanella, Deborah Holder, Michela Ottolia, Riccardo Olcese, Antonios Pantazis (2022) An epilepsy-associated K_V1.2 charge-transfer-center mutation impairs K_V1.2 and K_V1.4 trafficking Proceedings of the National Academy of Sciences of the United States of America, Vol. 119

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2021

Nina Ottosson, Malin Silverå Ejneby, Xiongyu Wu, Argel Estrada Mondragón, Michelle Nilsson, Urban Karlsson, Melanie Schupp, Salome Rognant, Thomas Andrew Jepps, Peter Konradsson, Fredrik Elinder (2021) Synthetic resin acid derivatives selectively open the hK(V)7.2/7.3 channel and prevent epileptic seizures Epilepsia, Vol. 62, p. 1744-1758

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Organisation

The Division of Cell and Neurobiology (CNB)

The Division of Cell and Neurobiology is a dynamic and innovative environment where we conduct research and teaching on both the structure and function of various cells as well as the nervous system and sensory organs.

Department of Biomedical and Clinical Sciences (BKV)

What characterizes the Department of Biomedical and Clinical Sciences (BKV) is the wide breadth of research and education. BKV is one of the largest departments at LiU with affiliation mainly to the Faculty of Medicine and Health Sciences.