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The AI tool Alphafold has been improved so that it can now predict the shape of very large and complex protein structures. Linköping University researchers have also succeeded in integrating experimental data into the tool.

Two of the grants were starting grants and eight were research project grants.

Breaking the code to understand why a protein takes on a specific shape has long been one of the major challenges in biology. A couple of years ago AI led to a breakthrough in this field. Björn Wallner’s research unites AI and bioinformatics.

Researchers at LiU have discovered a new mechanism by which substances can open a certain type of ion channel and in this way regulate nerve impulses. The discovery, published in the journal PNAS, may help in the development of future drugs.

Scientists have for the first time seen how the MYC protein, which plays a central role in cancer, binds to a key protein and controls important functions in cells. The new discovery may in the long term help in the development of new cancer drugs.