Emulate & understand: two faces of one coin. In our team, we strive to understand how tissue-resident cells, extracellular matrices, innervation, vasculature and immune cells cooperate and modulate each other’s responses to ensure organ-level functions and topographies. We use this information to create complex, complete 3D models of human organs and diseases. At the same time, we exploit these tools to advance our understanding of tissue development, homeostasis, and the onset of diseases. Our current focus is on the emulation of human dental tissues, human oral cancers, and the human trigeminal complex.
Bioengineering human oral tissues and disease models
