Björn Gylemo

Postdoc

Interested in the genetic contribution to sex-bias in disease. Investigating X-chromosome inactivation (XCI) in humans, primarily XCI escape fidelity and constitutional XCI skew. Currently exploring long-read sequencing.

Links to more information

For more information about my research see The Nestor lab webpage or my homepage.

Publications

2025

Björn Gylemo (2025)

The dynamics of X-chromosome inactivation in humans (Doctoral thesis, comprehensive summary)

https://dx.doi.org/10.3384/9789181181418

Björn Gylemo, Maike Bensberg, Colm Nestor (2025)

A whole-organism landscape of X-inactivation in humans eLIFE, Vol. 14, Article RP102701 (Article in journal)

https://dx.doi.org/10.7554/eLife.102701

Jeremie Subrini, Wazeer Varsally, Irina Balaguer Balsells, Maike Bensberg, Georgios Sioutas, Obah Ojarikre, Valdone Maciulyte, Björn Gylemo, Katharine Crawley, Katherine Courtis, Dirk G. de Rooij, James M. A. Turner (2025)

Systematic identification of Y-chromosome gene functions in mouse spermatogenesis Science, Vol. 387, p. 393-400 (Article in journal)

https://dx.doi.org/10.1126/science.ads6495

2024

Björn Gylemo, Maike Bensberg, Viktoria Hennings, Christina Lundqvist, Alessandro Camponeschi, Dóra Goldmann, Huan Zhang, Aida Selimovic, Antonio Lentini, Olov Ekwall, Colm Nestor (2024)

A landscape of X-inactivation during human T cell development Nature Communications, Vol. 15, Article 10527 (Article in journal)

https://dx.doi.org/10.1038/s41467-024-54110-7

2020

Karolos Douvlataniotis, Maike Bensberg, Antonio Lentini, Björn Gylemo, Colm Nestor (2020)

No evidence for DNA N-6-methyladenine in mammals Science Advances, Vol. 6, Article eaay3335 (Article in journal)

https://dx.doi.org/10.1126/sciadv.aay3335

Research group

En grafik över mänskliga xenosomer och de mänskliga xenosomerna.

The Nestor Lab

Our research aims to understand the function of DNA methylation in the biology of human CD4+ T-cells, and use this knowledge to dissect its role in disease.

News

Shedding light on sex differences in human disease

Researchers made an unexpected discovery while investigating genetically unique women. Their insights advance our understanding of our most enigmatic chromosome, the X chromosome.

Organisation

Teaser image for the Division BKH at BKV.

Division of Children's and Women's Health (BKH)

The Division of Children’s and Women’s Health consists of a number of different research and educational areas - obstetrics / gynecology and pediatrics.

Department of Biomedical and Clinical Sciences (BKV)

What characterizes the Department of Biomedical and Clinical Sciences (BKV) is the wide breadth of research and education. BKV is one of the largest departments at LiU with affiliation mainly to the Faculty of Medicine and Health Sciences.

Faculty of Medicine and Health Sciences (MEDFAK)

The Faculty of Medicine and Health Sciences conducts research and education within medicine, healthcare and public health.