Chuanwen Fan

Principal Research Engineer

Research

Bojmar Lab

Cancer is a systemic disease. Our research focuses on understanding crosstalk between different organs in the human body, and how this affects cancer progression. We focus mainly on gastrointestinal cancers and their common hepatic metastasis.

Publications

2026

Jonas Burman, Chuanwen Fan, Mohamed Elhusseiny, Paulina Velasco Riestra, Alexander Sandberg, Constantinos Zambirinis, Robert Kotan, Lucia Amorim Braz, Oliver Gimm, Linda Bojmar (2026)

Extracellular vesicles isolated from frozen whole blood show biomarker potential in small intestine neuroendocrine neoplasms iScience, Vol. 29, Article 116723 (Article in journal)

https://dx.doi.org/10.1016/j.isci.2026.116723

Feiwu Long, Wei Wang, Ya Liu, Chuanhua Yang, Hailiang Ren, Cuo Leng, Peng Xiong, Xinyue Tang, Liyao Hu, Lin Liu, Chuanwen Fan (2026)

MicroRNAs: Innovative Clinical Tools for Diagnosis, Prognosis, and Therapy in Colorectal Cancer MicroRNAs: Role in Cancer Progression, Diagnostics and Therapy, p. 487-532 (Chapter in book)

https://dx.doi.org/10.1007/978-3-032-08824-6_22

Yinchun Lv, Chenjia He, Qibing Xie, Feiwu Long, Chuanwen Fan (2026)

Understanding tumor heterogeneity: Implications for precision oncology and therapeutic strategies Biochimica et Biophysica Acta. CR. Reviews on Cancer, Vol. 1881, Article 189617 (Article, review/survey)

https://dx.doi.org/10.1016/j.bbcan.2026.189617

Yura Seo, Yoon Dae Han, Linda Bojmar, Kyung-A Kim, Yurin Seo, Taeyul K. Kim, Suho Lee, Yeleem Kim, Hye Bin Choi, Yujin H. Lim, Chae Hyun Kim, Alexander Sandberg, Chuanwen Fan, Pernille Lauritzen, Henrik Molina, Christopher Peralta, Jacob B. Geri, Colin Burdette, Dai Hoon Han, Heon Yung Gee, Insuk Lee, Jeon-Soo Shin, Hyunwook Kim, Leon Li, Gabriel C. Tobias, Inbal Wortzel, Sang Joon Shin, Hyo-Il Jung, Min Goo Lee, Soonmyung Paik, Robert E. Schwartz, Joong Bae Ahn, David Lyden, Han Sang Kim (2026)

Proteomic Profiling of Human Extracellular Vesicles Reveals Diagnostic Biomarkers for Colon Adenocarcinoma Journal of Extracellular Vesicles, Vol. 15, Article e70278 (Article in journal)

https://dx.doi.org/10.1002/jev2.70278

Huifen Ye, Ke Zhao, Yanfen Cui, Zhenhui Li, Huan Zhang, Min-Er Zhong, Chuanwen Fan, Haitao Huang, Nicholas J. Hawkins, Robyn L. Ward, Xiao-Feng Sun, Jinming Song, Zaiyi Liu, Jitendra Jonnagaddala, Tong Tong, Su Yao (2026)

Artificial intelligence-based tumor-stroma ratio quantification reveals prognostic value and stromal-driven immunosuppression in colorectal cancer: an international validation study Journal of Translational Medicine, Vol. 24, Article 269 (Article in journal)

https://dx.doi.org/10.1186/s12967-026-07681-6

2024

Yinchun Lv, Yulin Chen, Xue Li, Qiaorong Huang, Ran Lu, Junman Ye, Wentong Meng, Chuanwen Fan, Xianming Mo (2024)

Predicting psychiatric risk: IgG N-glycosylation traits as biomarkers for mental health Frontiers in Psychiatry, Vol. 15, Article 1431942 (Article in journal)

https://dx.doi.org/10.3389/fpsyt.2024.1431942

Yulin Chen, Xue Li, Ran Lu, Yinchun Lv, Yongzi Wu, Junman Ye, Jin Zhao, Li Li, Qiaorong Huang, Wentong Meng, Feiwu Long, Wei Huang, Qing Xia, Jianbo Yu, Chuanwen Fan, Xianming Mo (2024)

Vitamin B₁₂ protects necrosis of acinar cells in pancreatic tissues with acute pancreatitis MEDCOMM, Vol. 5, Article e686 (Article in journal)

https://dx.doi.org/10.1002/mco2.686

Guo Chen, Wei Wang, Xin Wei, Yulin Chen, Liao Peng, Rui Qu, Yi Luo, Shengyin He, Yugao Liu, Jie Du, Ran Lu, Siying Li, Chuanwen Fan, Sujun Chen, Yi Dai, Luo Yang (2024)

Single-cell transcriptomic analysis reveals that the APP-CD74 axis promotes immunosuppression and progression of testicular tumors Journal of Pathology, Vol. 264, p. 250-269 (Article in journal)

https://dx.doi.org/10.1002/path.6343

Yulin Chen, Xue Li, Ran Lu, Yinchun Lv, Junman Ye, Qiaorong Huang, Wentong Meng, Feiwu Long, Jonas Burman, Xianming Mo, Chuanwen Fan (2024)

Genetic insights into across pancreatitis types: the causal influence of immunoglobulin G N-glycosylation variants on disease risk Frontiers in Immunology, Vol. 15, Article 1326370 (Article in journal)

https://dx.doi.org/10.3389/fimmu.2024.1326370

Chuanwen Fan, Chao Fang, Wei Wang, Zhaoying Lv, Xueli Zhang, Feiwu Long, Zongze Jiang, Yuan Li, Hong Zhang, Zong-Guang Zhou, Cun Wang, Xiao-Feng Sun (2024)

Mismatch repair protein deficiency and its implications on distant metastasis in colorectal cancer: A comprehensive analysis Cancer Medicine, Vol. 13, Article e6994 (Article in journal)

https://dx.doi.org/10.1002/cam4.6994

Organisation

Department of Biomedical and Clinical Sciences (BKV)

What characterizes the Department of Biomedical and Clinical Sciences (BKV) is the wide breadth of research and education. BKV is one of the largest departments at LiU with affiliation mainly to the Faculty of Medicine and Health Sciences.

Faculty of Medicine and Health Sciences (MEDFAK)

The Faculty of Medicine and Health Sciences conducts research and education within medicine, healthcare and public health.