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Constantinos Zambirinis

Surgical oncologist studying novel approaches to quantify the biologic behavior, metastatic propensity, and organotropism of pancreatic cancer.

Description of area of expertise and research interests

Constantinos Zambirinis, is a surgeon-scientist, originally from Cyprus. He graduated from the University of Athens Medical School in Greece, and completed a Masters of Research in Translational Cancer Medicine at King's College London, UK. He spent 12 years in the U.S. during which he completed his surgical training at Harlem Hospital Center, NY, Warren Alpert Medical School of Brown University, RI, and the Rutgers Cancer Institute of New Jersey, NJ. He is double certified by the American Board of Surgery in General Surgery and Complex General Surgical Oncology.

While in the U.S., he also spent several years in the lab, first at New York University studying the role of inflammation in pancreatic carcinogenesis, and subsequently at Memorial Sloan Kettering Cancer Center where he focused on the immune and metabolic aspects of the liver pre-metastatic niche in pancreatic cancer.

His current research at LiU in collaboration with the Bojmar Lab focuses on immune-mediated mechanisms of pancreatic cancer progression and metastasis, and the development of novel approaches for radiomic and molecular profiling of pancreatic cancer in order to predict outcomes and tailor treatment to each patient's individual tumor.


Publications

2024

Linda Bojmar, Constantinos Zambirinis, Jonathan M. Hernandez, Jayasree Chakraborty, Lee Shaashua, Junbum Kim, Kofi Ennu Johnson, Samer Hanna, Gokce Askan, Jonas Burman, Hiranmayi Ravichandran, Jian Zheng, Joshua S. Jolissaint, Rami Srouji, Yi Song, Ankur Choubey, Han Sang Kim, Michele Cioffi, Elke van Beek, Carlie Sigel, Jose Jessurun, Paulina Velasco Riestra, Hakon Blomstrand, Carolin Jönsson, Anette Jönsson, Pernille Lauritzen, Weston Buehring, Yonathan Ararso, Dylanne Hernandez, Jessica P. Vinagolu-Baur, Madison Friedman, Caroline Glidden, Laetitia Firmenich, Grace Lieberman, Dianna L. Mejia, Naaz Nasar, Anders P. Mutvei, Doru M. Paul, Yaron Bram, Bruno Costa-Silva, Olca Basturk, Nancy Boudreau, Haiying Zhang, Irina R. Matei, Ayuko Hoshino, David Kelsen, Irit Sagi, Avigdor Scherz, Ruth Scherz-Shouval, Yosef Yarden, Moshe Oren, Mikala Egeblad, Jason S. Lewis, Kayvan Keshari, Paul M. Grandgenett, Michael A. Hollingsworth, Vinagolu K. Rajasekhar, John H. Healey, Bergthor Björnsson, Diane M. Simeone, David A. Tuveson, Christine A. Iacobuzio-Donahue, Jaqueline Bromberg, C. Theresa Vincent, Eileen M. O'Reilly, Ronald P. DeMatteo, Vinod P. Balachandran, Michael I. D'Angelica, T. Peter Kingham, Peter J. Allen, Amber L. Simpson, Olivier Elemento, Per A Sandström, Robert E. Schwartz, William R. Jarnagin, David Lyden (2024) Multi-parametric atlas of the pre-metastatic liver for prediction of metastatic outcome in early-stage pancreatic cancer Nature Medicine, Vol. 30, p. 2170-2180 (Article in journal) Continue to DOI

Research

Organisation