Estelle Barbier

Research

The Barbier Lab

We explore the neural circuits and molecular mechanisms that underlie alcohol use- and anxiety disorders. Additionally, we examine potential common mechanisms that may link these two disorders.

News

How fear memories get stuck in some brains

Researchers at Linköping University have discovered a biological mechanism that increases the strength with which fear memories are stored in the brain. The study identifies shared mechanisms behind anxiety and alcohol dependence.

Mechanism behind compulsive alcohol use revealed

A small group of nerve cells in the brain determines whether an individual continues to consume alcohol even when it has negative consequences. The scientists have identified a mechanism that may be a suitable target for treatment by medication.

People with alcohol dependency lack important enzyme

A research group under the leadership of Professor Markus Heilig has identified an enzyme whose production is turned off in nerve cells of the frontal lobe when alcohol dependence develops.

Publications

Publications in DiVA

2024

Michele Petrella, Anna Maria Borruto, Lorenzo Curti, Ana Domi, Esi Domi, Li Xu, Estelle Barbier, Alice Ilari, Markus Heilig, Friedbert Weiss, Guido Mannaioni, Alessio Masi, Roberto Ciccocioppo (2024) Pharmacological blockage of NOP receptors decreases ventral tegmental area dopamine neuronal activity through GABAB receptor-mediated mechanism Neuropharmacology, Vol. 248, Article 109866

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2023

Esi Domi, Riccardo Barchiesi, Estelle Barbier (2023) Epigenetic Dysregulation in Alcohol-Associated Behaviors: Preclinical and Clinical Evidence.

Ida Fredriksson, Pei-Jung Tsai, Aniruddha Shekara, Ying Duan, Sarah V. Applebey, Angelica Minier-Toribio, Ashley Batista, Jonathan J. Chow, Lindsay Altidor, Estelle Barbier, Carlo Cifani, Xuan Li, David J. Reiner, F. Javier Rubio, Bruce T. Hope, Yihong Yang, Jennifer M. Bossert, Yavin Shaham (2023) Role of ventral subiculum neuronal ensembles in incubation of oxycodone craving after electric barrier-induced voluntary abstinence Science Advances, Vol. 9, Article eadd8687

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Organisation

Center for Social and Affective Neuroscience - CSAN

Center for Social and Affective Neuroscience (CSAN) integrates knowledge and methodology from different areas of basic and clinical neuroscience.

Department of Biomedical and Clinical Sciences (BKV)

What characterizes the Department of Biomedical and Clinical Sciences (BKV) is the wide breadth of research and education. BKV is one of the largest departments at LiU with affiliation mainly to the Faculty of Medicine and Health Sciences.