Huan Zhang

Principal Research Engineer, Docent

Publications

2026

Huifen Ye, Ke Zhao, Yanfen Cui, Zhenhui Li, Huan Zhang, Min-Er Zhong, Chuanwen Fan, Haitao Huang, Nicholas J. Hawkins, Robyn L. Ward, Xiao-Feng Sun, Jinming Song, Zaiyi Liu, Jitendra Jonnagaddala, Tong Tong, Su Yao (2026)

Artificial intelligence-based tumor-stroma ratio quantification reveals prognostic value and stromal-driven immunosuppression in colorectal cancer: an international validation study Journal of Translational Medicine, Vol. 24, Article 269 (Article in journal)

https://dx.doi.org/10.1186/s12967-026-07681-6

2024

Björn Gylemo, Maike Bensberg, Viktoria Hennings, Christina Lundqvist, Alessandro Camponeschi, Dóra Goldmann, Huan Zhang, Aida Selimovic, Antonio Lentini, Olov Ekwall, Colm Nestor (2024)

A landscape of X-inactivation during human T cell development Nature Communications, Vol. 15, Article 10527 (Article in journal)

https://dx.doi.org/10.1038/s41467-024-54110-7

Samuel Schäfer, Martin Smelik, Oleg Sysoev, Yelin Zhao, Desiré Eklund, Sandra Lilja, Mika Gustafsson, Holger Heyn, Antonio Julia, Istvan A. Kovacs, Joseph Loscalzo, Sara Marsal, Huan Zhang, Xinxiu Li, Danuta Gawel, Hui Wang, Mikael Benson (2024)

scDrugPrio: a framework for the analysis of single-cell transcriptomics to address multiple problems in precision medicine in immune-mediated inflammatory diseases Genome Medicine, Vol. 16, Article 42 (Article in journal)

https://dx.doi.org/10.1186/s13073-024-01314-7

2023

Sandra Lilja, Xinxiu Li, Martin Smelik, Eun Jung Lee, Joseph Loscalzo, Pratheek Bellur Marthanda, Lang Hu, Mattias Magnusson, Oleg Sysoev, Huan Zhang, Yelin Zhao, Christopher Sjöwall, Danuta Gawel, Hui Wang, Mikael Benson (2023)

Multi-organ single-cell analysis reveals an on/off switch system with potential for personalized treatment of immunological diseases Cell Reports Medicine, Vol. 4, Article 100956 (Article in journal)

https://dx.doi.org/10.1016/j.xcrm.2023.100956

Mohamed Yassin Zaky Zaky Khalifa, Chuanwen Fan, Huan Zhang, Xiao-Feng Sun (2023)

Unraveling the Anticancer Potential of Statins: Mechanisms and Clinical Significance Cancers, Vol. 15, Article 4787 (Article, review/survey)

https://dx.doi.org/10.3390/cancers15194787

Research

En grafik över mänskliga xenosomer och de mänskliga xenosomerna.

The Nestor Lab

Our research aims to understand the function of DNA methylation in the biology of human CD4+ T-cells, and use this knowledge to dissect its role in disease.

News

Three scientists in lab coats work in a lab.

Digital twins an aid to give individual patients the right treatment at the right time

An international team of researchers have developed advanced computer models, or “digital twins”, of diseases, with the goal of improving diagnosis and treatment. They used one such model to identify the most important disease protein in hay fever.

The research group at Linköping University

Digital twins – an aid to tailor medication to individual patients

Advanced computer models of diseases can be used to improve diagnosis and treatment. The goal is to develop the models to “digital twins” of individual patients. Those twins may help to computationally identify and try the best medication.

Organisation

Teaser image for the Division BKH at BKV.

Division of Children's and Women's Health (BKH)

The Division of Children’s and Women’s Health consists of a number of different research and educational areas - obstetrics / gynecology and pediatrics.

Department of Biomedical and Clinical Sciences (BKV)

What characterizes the Department of Biomedical and Clinical Sciences (BKV) is the wide breadth of research and education. BKV is one of the largest departments at LiU with affiliation mainly to the Faculty of Medicine and Health Sciences.

Faculty of Medicine and Health Sciences (MEDFAK)

The Faculty of Medicine and Health Sciences conducts research and education within medicine, healthcare and public health.