Maria Jonson

Senior Research Coordinator

Publications

2023

Susanne Bauer, Chwen-Yu Chen, Maria Jonson, Lech Kaczmarczyk, Srivathsa Magadi, Walker Jackson (2023)

Cerebellar granule neurons induce Cyclin D1 before the onset of motor symptoms in Huntingtons disease mice Acta neuropathologica communications, Vol. 11, Article 17 (Article in journal)

https://dx.doi.org/10.1186/s40478-022-01500-x

2022

Lech Kaczmarczyk, Melvin Schleif, Lars Dittrich, Rhiannan H. Williams, Maruša Koderman, Vikas Bansal, Ashish Rajput, Theresa Schulte, Maria Jonson, Clemens Krost, Fabio J. Testaquadra, Stefan Bonn, Walker S. Jackson (2022)

Distinct translatome changes in specific neural populations precede electroencephalographic changes in prion-infected mice PLoS Pathogens, Vol. 18, Article e1010747 (Article in journal)

https://dx.doi.org/10.1371/journal.ppat.1010747

2021

Lech Kaczmarczyk, Nicole Reichenbach, Nelli Blank, Maria Jonson, Lars Dittrich, Gabor C. Petzold, Walker Jackson (2021)

Slc1a3-2A-CreERT2 mice reveal unique features of Bergmann glia and augment a growing collection of Cre drivers and effectors in the 129S4 genetic background Scientific Reports, Vol. 11, Article 5412 (Article in journal)

https://dx.doi.org/10.1038/s41598-021-84887-2

2019

Maria Jonson, Sofie Nyström, Alexander Sandberg, Marcus Carlback, Wojciech Michno, Jorg Hanrieder, Annika Starkenberg, K. Peter, Peter Nilsson, Stefan Thor, Per Hammarström (2019)

Amyloid fibril polymorphism and cell-specific toxicity in vivo Amyloid: Journal of Protein Folding Disorders, Vol. 26, p. 136-137 (Article in journal)

https://dx.doi.org/10.1080/13506129.2019.1582488

2018

Maria Jonsson, Sofie Nyström, Alexander Sandberg, Marcus Carlback, Wojciech Michno, Jorg Hanrieder, Annika Starkenberg, Peter Nilsson, Stefan Thor, Per Hammarström (2018)

Aggregated A beta 1-42 Is Selectively Toxic for Neurons, Whereas Glial Cells Produce Mature Fibrils with Low Toxicity in Drosophila Cell Chemical Biology, Vol. 25, p. 595-610 (Article in journal)

https://dx.doi.org/10.1016/j.chembiol.2018.03.006

Research

Illustration of various diseased centers in the brain.

Selective vulnerability to neurodegeneration

Neurodegenerative diseases cause stereotypical signs based on the specific brain region that is targeted. We try to understand how unaffected regions resist disease with the hope that these secrets can be transferred to vulnerable brain regions.

News

Alzheimer plaque affects different brain cells differently

Amyloid beta, a protein linked with Alzheimer's disease, has different properties in different cell types in the brains of fruit flies, according to a new study. It seems that certain cell types are hardly damaged at all by amyloid aggregates.