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Mikael Sigvardsson

Professor

News

illustration of cancer cells and red blood cells in blood vessel.

Possible explanation for long-term effects in leukemia survivors

Contrary to previous belief, stem cells, from which all new blood cells are formed, remain in bone marrow in the blood cancer type acute lymphocytic leukemia. But they have a hidden defect and lose their ability to form new blood cells.

Publications

2022

Telma Lanca, Jonas Ungerback, Clement Da Silva, Thorsten Joeris, Fatemeh Ahmadi, Julien Vandamme, Marcus Svensson-Frej, Allan Mci Mowat, Knut Kotarsky, Mikael Sigvardsson, William W. Agace (2022) IRF8 deficiency induces the transcriptional, functional, and epigenetic reprogramming of cDC1 into the cDC2 lineage Immunity, Vol. 55, p. 1431-1447.e11 Continue to DOI
Trine A. Kristiansen, Qinyu Zhang, Stefano Vergani, Elena Boldrin, Niklas Krausse, Oscar Andre, Pontus Nordenfelt, Mikael Sigvardsson, David Bryder, Jonas Ungerbaeck, Joan Yuan (2022) Developmental cues license megakaryocyte priming in murine hematopoietic stem cells BLOOD ADVANCES, Vol. 6, p. 6228-6241 Continue to DOI
Mikael Sigvardsson, Barbara L. Kee, Juan Carlos Zuniga-Pflucker, Michele K. Anderson (2022) Editorial: Molecular switches of the immune system: The E-protein/Id axis in hematopoietic development and function Frontiers in Immunology, Vol. 13, Article 1062734 Continue to DOI

Related Research

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Wallenberg Centre for Molecular Medicine at LiU

WCMM at LiU focuses on the medicine-technology interface, and build upon our existing strengths in research within medical technology, materials science and bioengineering.

Organisation

Molecular medicine and virology.

Division of Molecular Medicine and Virology (MMV)

At the division, the research involves studies on the molecular biology level as well as studies of biological effects on cells, on tissue, and organisms. We are also involved in medical and biomedical education programs.

Department of Biomedical and Clinical Sciences (BKV)

What characterizes the Department of Biomedical and Clinical Sciences (BKV) is the wide breadth of research and education. BKV is one of the largest departments at LiU with affiliation mainly to the Faculty of Medicine and Health Sciences.

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