Otmane Bouchatta

Postdoc

Postdoctoral scientist interested in the sensory physiology of pain in health and disease.

Sensation of human pain: Perception and afferent coding

In my PhD, I have been investigating the mechanisms underlying the comorbidity between attention deficit/hyperactivity disorder (ADHD) and pain. I used behavioral approaches, morphological analysis and in vivo electrophysiology combined with optogenetics in mice.
Currently, I aim to decipher how individual sensory afferents encode painful stimuli by using microneurography (in vivo electrophysiology) and psychophysics in humans.

Publications

Key publications

Bouchatta O, Aby F, Sifeddine W, Bouali-Benazzouz R, Brochoire L, Manouze H, Fossat P, Ba-M’Hamed S, Bennis M, Landry M (2022). Pain hypersensitivity in a pharmacological mouse model of Attention-Deficit/Hyperactivity Disorder. Proceedings of the National Academy of Sciences, 119(30): e2114094119. doi:10.1073/pnas.2114094119.
Aby F, Lorenzo LE, Grivet Z, Bouali-Benazzouz R, Martin H, Valerio S, Whitestone S, Isabel D, Idi W, Bouchatta O, De Deurwaerdere P, Godin AG, Herry C, Fioramonti X, Landry M, De Koninck Y and Fossat P (2022). Switch of serotonergic descending inhibition into facilitation by a spinal chloride imbalance in neuropathic pain. Science Advances, 8(30): eabo0689. doi: 10.1126/sciadv.abo0689.

2023

Organisation

Center for Social and Affective Neuroscience - CSAN

Center for Social and Affective Neuroscience (CSAN) integrates knowledge and methodology from different areas of basic and clinical neuroscience.

Department of Biomedical and Clinical Sciences (BKV)

What characterizes the Department of Biomedical and Clinical Sciences (BKV) is the wide breadth of research and education. BKV is one of the largest departments at LiU with affiliation mainly to the Faculty of Medicine and Health Sciences.