Sadaf Kalsum

Publications

2026

Qiao Qin, Zhuoheng Liu, Chen-Yi Cheung, Jinxu Xu, Sadaf Kalsum, Hang Yu, Maria Lerm, Hongri Gong, Matthew McNeil, Gregory M. Cook, Susanna Brighenti, Yang Zhou, Xiaoyun Lu (2026) Design, Synthesis, and Antimicrobial Activity of Novel Cyt-bd Inhibitors Targeting Energy Compensation in Mycobacterium tuberculosis ACS Medicinal Chemistry Letters (Article in journal) https://dx.doi.org/10.1021/acsmedchemlett.6c00310

2025

Sylwia Krol, Terezia Kovalova, Mateusz Janczak, Sadaf Kalsum, Mira Akber, Martin Hogbom, Susanna Brighenti, Pia Adelroth, Peter Brzezinski (2025) Mycobacterial respiratory chain enzymes and growth are inhibited by decylubiquinone Communications Biology, Vol. 9, Article 43 (Article in journal) https://dx.doi.org/10.1038/s42003-025-09309-9

Sadaf Kalsum, Ruilan Xu, Mira Akber, Shengjie Huang, Maria Lerm, Yuqing Chen, Magda Lourda, Yang Zhou, Susanna Brighenti (2025) Dual GSK-3ß/HDAC Inhibitors Enhance the Efficacy of Macrophages to Control Mycobacterium tuberculosis Infection Biomolecules, Vol. 15, Article 550 (Article in journal) https://dx.doi.org/10.3390/biom15040550

2024

Sadaf Kalsum, Mira Akber, Marco Giulio Loreti, Blanka Andersson, Eva Kristin Danielson, Maria Lerm, Susanna Brighenti (2024) Sirtuin inhibitors reduce intracellular growth of M. tuberculosis in human macrophages via modulation of host cell immunity Scientific Reports, Vol. 14, Article 28150 (Article in journal) https://dx.doi.org/10.1038/s41598-024-79136-1

2022

Sadaf Kalsum, Magdalena Otrocka, Blanka Andersson, Amanda Welin, Thomas Schön, Annika Jenmalm-Jensen, Thomas Lundback, Maria Lerm (2022) A high content screening assay for discovery of antimycobacterial compounds based on primary human macrophages infected with virulent Mycobacterium tuberculosis Tuberculosis, Vol. 135, Article 102222 (Article in journal) https://dx.doi.org/10.1016/j.tube.2022.102222