Sanne Toivainen Eloff

Research Engineer

Publications

2025

Sanne Toivainen Eloff (2025)

Compulsive Alcohol Self-Administration in Rats: Neural Mechanisms and Sex Differences (Doctoral thesis, comprehensive summary)

https://dx.doi.org/10.3384/989180759816

2024

Sanne Toivainen Eloff, Michele Petrella, Li Xu, Esther Visser, Tamina Weiss, Sofia Vellere, Zane Zeier, Claes Wahlestedt, Estelle Barbier, Esi Domi, Markus Heilig (2024)

Generation and Characterization of a Novel Prkcd-Cre Rat Model Journal of Neuroscience, Vol. 44, Article e0528242024 (Article in journal)

https://dx.doi.org/10.1523/JNEUROSCI.0528-24.2024

Sanne Toivainen Eloff, Li Xu, Francesco Gobbo, Andrea Della Valle, Andrea Coppola, Markus Heilig, Esi Domi (2024)

Different mechanisms underlie compulsive alcohol self-administration in male and female rats Biology of Sex Differences, Vol. 15, Article 17 (Article in journal)

https://dx.doi.org/10.1186/s13293-024-00592-5

2023

Esi Domi, Li Xu, Sanne Toivainen Eloff, Joost Wiskerke, Andrea Coppola, Lovisa Holm, Eric Augier, Michele Petrella, Markus Heilig (2023)

Activation of GABA(B) receptors in central amygdala attenuates activity of PKC delta plus neurons and suppresses punishment-resistant alcohol self-administration in rats Neuropsychopharmacology, Vol. 48, p. 1386-1395 (Article in journal)

https://dx.doi.org/10.1038/s41386-023-01543-1

2021

Esi Domi, Li Xu, Sanne Toivainen, Anton Nordeman, Francesco Gobbo, Marco Venniro, Yavin Shaham, Robert O. Messing, Esther Visser, Michel C. van den Oever, Lovisa Holm, Estelle Barbier, Eric Augier, Markus Heilig (2021)

A neural substrate of compulsive alcohol use Science Advances, Vol. 7, Article eabg9045 (Article in journal)

https://dx.doi.org/10.1126/sciadv.abg9045

Research

The Heilig Translational Psychiatry Lab: Preclinical group

We use animal models to discover molecular and neural mechanisms that cause a progression into alcohol addiction, and to identify novel targets for pharmacological addiction treatments.

Organisation

researcher applies a very thin filament to the hand to measure properties of nerve cells in the skin

Center for Social and Affective Neuroscience (CSAN)

Department of Biomedical and Clinical Sciences (BKV)

What characterizes the Department of Biomedical and Clinical Sciences (BKV) is the wide breadth of research and education. BKV is one of the largest departments at LiU with affiliation mainly to the Faculty of Medicine and Health Sciences.

News

Mechanism behind compulsive alcohol use revealed

A small group of nerve cells in the brain determines whether an individual continues to consume alcohol even when it has negative consequences. The scientists have identified a mechanism that may be a suitable target for treatment by medication.