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Immune cells are behind the depression experienced in inflammation

The findings from a new study on mice suggest that special immune cells found in the brain, microglial cells, contribute to the negative mood experienced during several neurological diseases, and maybe also depression.

Immune cells in the brain – a link between inflammation and depression

One in four people in Sweden will be affected at some time by a depression so serious that it requires treatment. Wouldn’t it be great if we could understand the brain circuits that determine the way we feel, and find new and better treatments?

Reward and unease are closely linked in the brain

Mice that lack a certain receptor in the brain are attracted to situations associated with discomfort, such as inflammation and nausea. The finding by researchers from Linköping University has been published in the Journal of Clinical Investigation.

Keep the fever, but feel better

Fever and poor appetite are one thing. But why do we become depressed and feel so badly when influenza strikes? Neurological researchers at Linköping University have demonstrated at the molecular level how inflammations affect mood.

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Immune cells are behind the depression experienced in inflammation

Immune cells in the brain – a link between inflammation and depression

Reward and unease are closely linked in the brain

Keep the fever, but feel better

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