CSAN unites research groups in psychiatry, neurobiology, clinical neurophysiology and neuroeconomics.
Addiction leads to a progressively increased choice of drugs over healthy rewards such as food and social interaction. We investigate the mechanisms and circuits driving individual variability to substance use disorder.
We investigate how the experience of “self” is generated by the brain and body – and what happens if self-other-distinction is altered in psychiatric conditions or through experimental interventions.
At the Engblom Lab, we investigate the mechanisms and circuits underpinning the aversive affective states and the depressive symptoms accompanying inflammatory diseases and major depression.
We use brain imaging, behavior analysis and pharmacology to study how a breakdown of coping with stress and regulating negative emotions results in disorders such as depression, post-traumatic stress and addiction.
We use animal models to discover molecular and neural mechanisms that cause a progression into alcohol addiction, and to identify novel targets for pharmacological addiction treatments.
We explore how humans perceive and react to stressful or emotional stimuli in order to better understand how these processes go awry in psychiatric diseases such as post-traumatic stress disorder.
Human touch is a powerful way of evoking emotions. What is the functional significance of the system for ultrafast nociceptors that we recently discovered? How does the nervous system distinguish social and self-touch? Our lab is looking for answers.
External stimuli in concert with internal state guide behaviors, moods and choices. Deciphering how sensory representation is altered by injury, might have major implications for the treatment of somatosensory dysfunctions like chronic pain.
Our research group addresses nonsuicidal self-injury (NSSI) which is a significant mental health issue in adolescents and linked with impairments in emotion regulation. We are dedicated to developing novel approaches for preventing and