CSAN unites research groups in psychiatry, neurobiology, clinical neurophysiology and neuroeconomics.
Addiction leads to a progressively increased choice of drugs over healthy rewards such as food and social interaction. We investigate the mechanisms and circuits driving individual variability to substance use disorder.
We explore the neural circuits and molecular mechanisms that underlie alcohol use- and anxiety disorders. Additionally, we examine potential common mechanisms that may link these two disorders.
We investigate how the experience of “self” is generated by the brain and body – and what happens if self-other-distinction is altered in psychiatric conditions or through experimental interventions.
At the Engblom Lab, we investigate the mechanisms and circuits underpinning the aversive affective states and the depressive symptoms accompanying inflammatory diseases and major depression.
The main challenge of addiction treatment is high relapse rates during abstinence. We use preclinical models to study the mechanisms and circuits that mediate opioid relapse and craving.
We use brain imaging, behavior analysis and pharmacology to study how a breakdown of coping with stress and regulating negative emotions results in disorders such as depression, post-traumatic stress and addiction.
We use animal models to discover molecular and neural mechanisms that cause a progression into alcohol addiction, and to identify novel targets for pharmacological addiction treatments.
We explore genetic and environmental risk and follow clinical outcomes in addiction medicine using national and regional Swedish registers with the overall aim to improve healthcare for addiction.
Human touch is a powerful way of evoking emotions. What is the functional significance of the system for ultrafast nociceptors that we recently discovered? How does the nervous system distinguish social and self-touch? Our lab is looking for answers.
External stimuli in concert with internal state guide behaviors, moods and choices. Deciphering how sensory representation is altered by injury, might have major implications for the treatment of somatosensory dysfunctions like chronic pain.
Our research group addresses nonsuicidal self-injury (NSSI) which is a significant mental health issue in adolescents and linked with impairments in emotion regulation. We are dedicated to developing novel approaches for preventing and treating NSSI.