Neuroinformatics -Bridging Cognition, AI, and Digital Health

Robot with tablet next to neural network and app interface – symbolising neuroinformatics.
AI-generated image.

Neuroinformatics explores how technology can enhance understanding and support of the human brain and behavior. It combines machine learning, apps, games, and robotics to study cognition, emotion, and interaction. These interactive tools show potential to improve care, learning, and well-being.

At the intersection of neuroscience and informatics lies Neuroinformatics—a domain where digital tools, AI-driven systems, and assistive technologies converge to support neurological health. Drawing on our prior work in multiple sclerosis, cognitive decline, gamified testing, and social robotics, this emerging research pillar builds on our strengths in app design, user-centered technologies, and clinical collaboration. Moving forward, we are committed to deepening our investigations into clinical data integration and gamified cognitive assessment, aiming to create meaningful, validated tools for early detection, monitoring, and intervention.

Mission

  • Strengthen clinical foundations: Integrate clinical testing data with digital tools for cognitive decline.
  • Gamified cognitive assessments: Develop validated game-based testing environments for early detection and monitoring of cognitive impairment.
  • Broaden assistive scope: Combine apps and robotics to enhance autonomy and care in elderly and neurologically vulnerable populations.
  • Interdisciplinary synergy: Amplify collaborations among neuroscience, human-computer interaction (HCI), AI, and clinical partners to ensure both usability and validity.

AppS - Patient applications

Apps for patients and users are increasingly developed to support self-management of chronic conditions such as Multiple Sclerosis (MS). The series of studies describes the design and evaluation of a mobile application that helps individuals monitor symptoms, track activities, manage stress, and prepare for medical appointments. Insights from patients, healthcare professionals, and social media discussions guided the design process, ensuring that the solution addressed real user needs. The application was refined through iterative prototyping and usability testing, leading to improvements in functionality and data visualization. Overall, it illustrates how digital health tools can enhance patient engagement, motivation, and self-awareness in everyday disease management.

Design principles

Designprinciper för AppS - patientcentrerade appar
Bild: Martine Oppegaard Jakobsen, University of Bergen

Research participants

Deltagare i studie om digital egenvård vid kroniska sjukdomar.

Bild: Martine Oppegaard Jakobsen, University of Bergen

Cover of publication ''
Martine Oppegaard Jakobsen, Ankica Babic (2019)

HEALTH INFORMATICS VISION: FROM DATA VIA INFORMATION TO KNOWLEDGE , s.360-363 Continue to DOI

Machine learning in cognitive decline

There are emerging AI-based methods for the early detection of cognitive decline, drawing on imaging, clinical, and language data. These approaches demonstrate high diagnostic potential and continue to improve with advances in deep learning. Together, they point toward more accurate and accessible tools for supporting early intervention in cognitive health.

Översikt av AI-baserade ML-metoder för kognitiv minskning.
Bild: Martine Oppegaard Jakobsen, University of Bergen

Cover of publication ''
Arash Gharehbaghi, Ankica Babic (2025)

Studies in Health Technology and Informatics , s.46-50 Continue to DOI

Gamified cognitive assessments

There is growing interest in digital systems and games for cognitive testing and training in older adults, yet validated self-assessment tools remain limited. Clinical solutions are more reliable but often inaccessible, while many apps lack scientific validation despite wide availability. Future development should combine clinical rigor with user-centered design to create engaging, evidence-based tools for cognitive health in aging.

Kollage av digitala system och spel för kognitiv testning och träning hos äldre.

Iterations of Mini-Cog test

We have developed two digital artifacts for testing cognitive decline based on the medically validated Mini-Cog test. The first version is a simple, clinician-oriented tool, while the second integrates gamification elements such as narratives, rewards, and emojis to increase engagement.

Tre versioner av ett digitalt verktyg för att testa kognitiv nedgång med Mini-Cog: från enkel textinmatning (nov 2023), till färgglada knappar (mars 2024), till en spelifierad version med ikoner och emojis (april 2024).

This figure illustrates the clock-drawing component of the Mini-Cog test. The left image shows the initial step of setting the clock face, while the right image depicts the task of assigning the correct time by positioning the clock hands.

Två steg i Mini-Cog-klocktestet: en tom urtavla och en med visare som visar tiden.
Bild: Anton Nydal, University of Bergen, Norge

User experience results

User feedback and usability testing indicate that the gamified version enhances enjoyment and interaction while preserving the test’s diagnostic integrity.

Två stapeldiagram som visar användarupplevelse för det gamifierade Mini-Cog-testet, uppdelat efter åldersgrupp och enhet.
Bild: Martine Oppegaard Jakobsen, University of Bergen
Cover of publication ''
Krister Bauge, Ankica Babic (2025)

Studies in Health Technology and Informatics , s.178-182 Continue to DOI

Cover of publication ''
Ankica Babic, Anton Nydal, Karin Wårdell (2025)

Current Directions in Biomedical Engineering , Vol.11 , s.374-376 Continue to DOI

Robotics

The integration of assistive robots in Japan nursing care through interviews and observations in three nursing homes. Robots such as Paro, Pepper, and Qoobo were evaluated for their roles and user experiences. The findings highlight user satisfaction and the therapeutic and entertainment value of these robots. Their potential to support elderly care is clear. However, better strategies are needed to fully utilize and integrate them into daily practice.

Tre typer av vårdrobotar: Paro, Pepper och Qoobo.

Cover of publication ''
Markus Kolstad, Natsu Yamaguchi, Ankica Babic, Yoko Nishihara (2020)

The Importance of Health Informatics in Public Health during a Pandemic , s.183-186 Continue to DOI

Researchers

Organisation