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Many women treated for breast cancer using taxanes, a type of cytostatic drug, often experience side effects in the nervous system. Researchers at LiU have developed a tool that can predict the risk level for each individual.

The aim of our research is to identify, validate and implement genetic markers or other biomarkers to predict drug metabolism or drug effects.

In this project we work with next generation sequencing to identify causative variant, prediction and prevalence, as well as investigating the functional consequence of different genetic variants found.

We work with the prediction of pharmacokinetics of new targeted treatments and side effects of classical chemotherapy in the treatment of cancer.

Misuse of opioids and new psychoactive substances are a clear and present health danger. There is a great need to establish ways to assess the toxicity and pharmacology of these new drugs for a correct risk assessment and evaluation.

NPS, new psychoactive substances, are substances developed to affect the brain in a similar way to illegal drugs. Researchers have set up a rapid method for measuring the effect of new NPS and provide scientific basis for narcotics classification.

Researchers are involved in the campaign to make designer drugs illegal as quickly as possible. Henrik Gréen investigates how new psychoactive substances act, and why some designer drugs are more lethal than others.