Search liu.se

Our research aims to understand the function of DNA methylation in the biology of human CD4+ T-cells, and use this knowledge to dissect its role in disease.

Colm Nestor has been awarded the 2025 Onkel Adam Prize for outstanding research at the Faculty of Medicine and Health Sciences. One of his research areas is gender differences in susceptibility to autoimmune diseases and infections.

Researchers made an unexpected discovery while investigating genetically unique women. Their insights advance our understanding of our most enigmatic chromosome, the X chromosome.

A new study has shown that the tumour-inhibiting gene TET2 is silenced in a large fraction of cases of acute lymphoblastic leukemia (ALL) in children. The scientists show that the gene can be reactivated by an existing drug.

Associate professor Colm Nestor has been awarded a Consolidator Grant from the European Research Council (ERC) of approximately SEK 22 million over the next 5 years. The funding will be used to research sex bias in human disease.

A puzzling modification of DNA that is common in bacteria is not present in humans or other mammals. Scientists at LiU show that previous detection in animals was probably due to limitations of the technology used and bacterial contamination.

An error in one of the most widely used methods in epigenetics research can cause misleading results. This may have major significance in the research field. The findings by researchers at LiU are published in Nature Methods.