My research aims to advance hematological laboratory diagnostics by increasing objectivity, efficiency, and clinical utility. A key objective is to reduce reliance on manual and time‑consuming microscopy, while extracting more standardized and information‑rich data from routine blood samples.
A central methodology is imaging flow cytometry, a technology that combines the high throughput of flow cytometry with the morphological resolution of fluorescence microscopy. This approach enables quantitative analysis of both phenotypic and structural cellular features in thousands of cells in flow, creating new opportunities for automation and refinement of hematological diagnostics.
The research includes the development of analytical strategies for more objective and reproducible leukocyte differentiation, with the aim of improving early triage and preliminary classification in cases of abnormal blood findings. Another core focus is platelet disorders, particularly immune thrombocytopenia (ITP), where imaging flow cytometry is used to identify cellular and morphological patterns that may contribute to more precise diagnostics than today’s largely exclusion‑based approaches. The increased level of cellular detail also provides opportunities to explore underlying pathophysiological mechanisms and to identify previously unrecognized processes in ITP.
I combine research with clinical training as a resident physician in clinical chemistry within Region Östergötland, ensuring strong clinical relevance of the research. I have been active at Linköping University as a research group leader since 2019 and was appointed WCMM Associated Clinical Fellow in 2025.
