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Carl-Fredrik Mandenius

Professor Emeritus

Professor emeritus

Presentation

Carl-Fredrik Mandenius is emeritus professor in engineering biology at Linköping University. He is M.Eng. and D.Eng. in applied biochemistry and biotechnology from Lund University. He has been heading the Biotechnology Division at IFM between 1999 and 2022. His research is focused on bioengineering design in education, research, and industrial development. Specific interests are in bioprocess monitoring, stem cell technology, and mathematical modelling of biological systems in bioprocessing and medicine. Mandenius is also much involved in editorship in engineering biology.

Publications

2025

Jonas Christoffersson, H. Kempf, R. Zweigerdt, Carl-Fredrik Mandenius (2025) Evaluating the Effect of Drug Compounds on Cardiac Spheroids Using the Cardiac Cell Outgrowth Assay in a Microphysiological System Methods in Molecular Biology, p. 249-257 (Chapter in book) Continue to DOI
J. A. Ross, Carl-Fredrik Mandenius (2025) Cell-Based Assays Using Derived Human-Induced Pluripotent Cells in Drug Discovery and Development Methods in Molecular Biology, p. 1-14 (Chapter in book) Continue to DOI

2024

Bertil Kågedal, Carl-Fredrik Mandenius (2024) A physiological model for iohexol plasma clearance supporting diagnostics of kidney function Clinica Chimica Acta, Vol. 561, Article 119823 (Article in journal) Continue to DOI
Thuy Tran, Robert Gustavsson Lindberg, Erik Martinsson, Filip Bergqvist, Andreas Axen, Ingemar Lundström, Carl-Fredrik Mandenius, Daniel Aili (2024) In-line fiber optical sensor for detection of IgG aggregates in affinity chromatography Journal of Chromatography A, Vol. 1730, Article 465129 (Article in journal) Continue to DOI
Chanyong Park, Wanyoung Lim, Ryungeun Song, Jeonghun Han, Daeun You, Sangmin Kim, Jeong Eon Lee, Danny van Noort, Carl-Fredrik Mandenius, Jinkee Lee, Kyung-A. Hyun, Hyo-Il Jung, Sungsu Park (2024) Efficient separation of large particles and giant cancer cells using an isosceles trapezoidal spiral microchannel The Analyst, Vol. 149, p. 4496-4505 (Article in journal) Continue to DOI

News

close-up of the hydrogel

12 February 2019

New gel for liver cell culture on microchips

Scientists at LiU have developed a hydrogel, that have properties similar to the natural environment of cells in the body. It can be adapted to the requirements of difficult-to-culture cell types, and to produce organ-like structures on a microchip.

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