Photo of Heriberto Rodriguez Martinez

Heriberto Rodriguez Martinez

Professor Emeritus

My research focus on the interactions between the seminal fluid bearing spermatozoa with the female genital tract and the oocytes, before and during fertilization. 

Reproduction, a major sentinel of the health of animals and humans

Environmental and societal changes, including an increased stressful lifestyle, constrain reproduction; a major sentinel of the health of ecosystems, animals and humans.

My research focus on the interactions between the seminal fluid bearing spermatozoa with the female genital tract and the oocytes, before and during fertilization. This includes determining how the seminal fluid is able to signal and elicit genomic shifts in the female genitalia in relation to maternal immune tolerance to the foreign cells and proteins it contains.

My research, covering areas of comparative reproductive biology/biotechnology, andrology and cryobiology, pursues disclosure of valuable biomarkers for male fertility, of the complicated signaling system that the transcriptome and proteome of the seminal fluid is built and how they are constrained by cryopreservation.

Reinforcement of our diagnostic capacity in andrology and assisted reproductive techniques is still my leading star.

Publications

2026

Carolina G. Cabrera-Gomez, David Gascon-Collado, Paula Blanco-Cueto, Belen Pequeno, Heriberto Rodriguez Martinez, Cristina Martinez Serrano (2026) Stage-specific remodeling of wingless-related integration sites (WNT) signaling during oocyte-to-embryo transition in pigs Journal of Animal Science, Vol. 104, Article skag134 (Article in journal) https://dx.doi.org/10.1093/jas/skag134
Manuela Garcia-Canovas, Adelina Lopez-Jara, Inmaculada Parrilla, Alejandro Gonzalez-Plaza, Heriberto Rodriguez-Martinez, Maria A. Gil, Cristina Cuello, Emilio A. Martinez (2026) Correction: Exposure of in vitro maturing pig oocytes to exogenous interleukin-6 is associated with transcriptomic differences in the resulting blastocysts, with enrichment of developmental signaling pathways (vol 12, 1716588, 2026) Frontiers in Veterinary Science, Vol. 13, Article 1802076 (Article in journal) https://dx.doi.org/10.3389/fvets.2026.1802076
Manuela Garcia-Canovas, Adelina Lopez-Jara, Inmaculada Parrilla, Alejandro Gonzalez-Plaza, Heriberto Rodriguez-Martinez, Maria A. Gil, Cristina Cuello, Emilio A. Martinez (2026) Exposure of in vitro maturing pig oocytes to exogenous interleukin-6 is associated with transcriptomic differences in the resulting blastocysts, with enrichment of developmental signaling pathways Frontiers in Veterinary Science, Vol. 12, Article 1716588 (Article in journal) https://dx.doi.org/10.3389/fvets.2025.1716588
Isabel Barranco, Pablo Martinez-Diaz, Ana Parra, Maria Jose Martinez-Alborcia, Xiomara Lucas, Heriberto Rodriguez-Martinez, Jordi Roca (2026) Proteomic profiling of porcine seminal extracellular vesicles reveals potential in vivo fertility biomarkers Andrology, Vol. 14, p. 555-570 (Article in journal) https://dx.doi.org/10.1111/andr.70089

2025

A. Vicente-Carrillo, E. de Mercado de la Peña, A. Martín San Juan, H. Nieto-Cristóbal, Heriberto Rodriguez-Martinez, M. Álvarez-Rodríguez (2025) Spermatology: Current Methods to Study Sperm Classical Variables Methods in Molecular Biology, p. 3-27 (Chapter in book) https://dx.doi.org/10.1007/978-1-0716-4406-5_1

News

Publications

2026

Carolina G. Cabrera-Gomez, David Gascon-Collado, Paula Blanco-Cueto, Belen Pequeno, Heriberto Rodriguez Martinez, Cristina Martinez Serrano (2026) Stage-specific remodeling of wingless-related integration sites (WNT) signaling during oocyte-to-embryo transition in pigs Journal of Animal Science, Vol. 104, Article skag134 (Article in journal) https://dx.doi.org/10.1093/jas/skag134
Manuela Garcia-Canovas, Adelina Lopez-Jara, Inmaculada Parrilla, Alejandro Gonzalez-Plaza, Heriberto Rodriguez-Martinez, Maria A. Gil, Cristina Cuello, Emilio A. Martinez (2026) Correction: Exposure of in vitro maturing pig oocytes to exogenous interleukin-6 is associated with transcriptomic differences in the resulting blastocysts, with enrichment of developmental signaling pathways (vol 12, 1716588, 2026) Frontiers in Veterinary Science, Vol. 13, Article 1802076 (Article in journal) https://dx.doi.org/10.3389/fvets.2026.1802076
Manuela Garcia-Canovas, Adelina Lopez-Jara, Inmaculada Parrilla, Alejandro Gonzalez-Plaza, Heriberto Rodriguez-Martinez, Maria A. Gil, Cristina Cuello, Emilio A. Martinez (2026) Exposure of in vitro maturing pig oocytes to exogenous interleukin-6 is associated with transcriptomic differences in the resulting blastocysts, with enrichment of developmental signaling pathways Frontiers in Veterinary Science, Vol. 12, Article 1716588 (Article in journal) https://dx.doi.org/10.3389/fvets.2025.1716588

My research

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