Irene Hiniesto Iñigo

Publications

2025

Irene Hiniesto Iñigo (2025) Modulation of the cardiac Kv7.1/KCNE1 channel by endocannabinoids and derivatives in the context of Long QT Syndrome

Irene Hiniesto Iñigo, Akshay Sridhar, Julien Louradour, Alicia de La Cruz Fernandez, Siri Amalia Lundholm, Amaia Jauregi Miguel, Federica Giannetti, Luca Sala, Katja E. Odening, Peter Larsson, Nina Ottosson, Sara Liin (2025) Rescue of loss-of-function long QT syndrome-associated mutations in K_V7.1/KCNE1 by the endocannabinoid N-arachidonoyl-L-serine (ARA-S) British Journal of Pharmacology (Article in journal) Continue to DOI

2024

Irene Hiniesto Iñigo, Veronika Linhart, Ali Kusay, Sara Liin (2024) The endocannabinoid ARA-S facilitates the activation of cardiac Kv7.1/KCNE1 channels from different species CHANNELS, Vol. 18, Article 2420651 (Article in journal) Continue to DOI

2023

Alicia De la Cruz, Xiaoan Wu, Quinn C. C. Rainer, Irene Hiniesto-Iñigo, Marta E. E. Perez, Isak Edler, Sara Liin, H. Peter Larsson (2023) Pharmacological Screening of Kv7.1 and Kv7.1/KCNE1 Activators as Potential Antiarrhythmic Drugs in the Zebrafish Heart International Journal of Molecular Sciences, Vol. 24, Article 12092 (Article in journal) Continue to DOI

Irene Hiniesto Iñigo, Laura M. Castro-Gonzalez, Valentina Corradi, Mark A. Skarsfeldt, Samira Yazdi, Siri Amalia Lundholm, Johan Nikesjö, Sergei Yu Noskov, Bo Hjorth Bentzen, D. Peter Tieleman, Sara Liin (2023) Endocannabinoids enhance hKV7.1/KCNE1 channel function and shorten the cardiac action potential and QT interval EBioMedicine, Vol. 89 (Article in journal) Continue to DOI