Irene Hiniesto Iñigo

Publications

2026

Ali Kusay, Michael Pökl, Irene Hiniesto Iñigo, Akshay Sridhar, L. Delemotte, Sara Liin (2026) Cannabidiol inhibits both human KV7.1 and KV7.1/KCNE1 channels through distinct sites Acta Pharmacologica Sinica (Article in journal) https://dx.doi.org/10.1038/s41401-025-01742-0

2025

Julien Louradour, Tibor Hornyik, Alicia de La Cruz Fernandez, Irene Hiniesto Iñigo, Nicolo Alerni, Miriam Barbieri, Ruben Lopez, Stefanie Perez-Feliz, Lluis Matas, Saranda Nimani, Lucilla Giammarino, Gideon Koren, Manfred Zehender, Michael Brunner, Sara I Liin, H Peter Larsson, Katja E. Odening (2025) Beneficial action potential duration-shortening effects, but deleterious negative inotropism of IKs-activator docosahexaenoyl glycine in long QT syndrome type 2 Europace, Vol. 27, Article euaf168 (Article in journal) https://dx.doi.org/10.1093/europace/euaf168

Irene Hiniesto Iñigo (2025) Modulation of the cardiac Kv7.1/KCNE1 channel by endocannabinoids and derivatives in the context of Long QT Syndrome (Doctoral thesis, comprehensive summary) https://dx.doi.org/10.3384/9789181180343

Irene Hiniesto Iñigo, Akshay Sridhar, Julien Louradour, Alicia de La Cruz Fernandez, Siri Amalia Lundholm, Amaia Jauregi Miguel, Federica Giannetti, Luca Sala, Katja E. Odening, Peter Larsson, Nina Ottosson, Sara Liin (2025) Rescue of loss-of-function long QT syndrome-associated mutations in K_V7.1/KCNE1 by the endocannabinoid N-arachidonoyl-L-serine (ARA-S) British Journal of Pharmacology, Vol. 182, p. 2861-2877 (Article in journal) https://dx.doi.org/10.1111/bph.70008

2024

Irene Hiniesto Iñigo, Veronika Linhart, Ali Kusay, Sara Liin (2024) The endocannabinoid ARA-S facilitates the activation of cardiac Kv7.1/KCNE1 channels from different species CHANNELS, Vol. 18, Article 2420651 (Article in journal) https://dx.doi.org/10.1080/19336950.2024.2420651