Thomas Ederth is a Senior lecturer and Docent (Associate Professor) in Molecular Physics, and conducts research in surface chemistry, predominantly basic research related to interactions of biological material (organisms or biomolecules) with surfaces. The research activities build on a common ground of knowledge and methods for analysis of surfaces and interfaces, which is applied to projects in different disciplines. Of the used methods, vibrational spectroscopy and neutron reflectometry are of particular importance. Current research includes projects in these areas:
- Marine biofoling and marine bioadhesion
- Fouling-resistant polymers
- Biocompatibility and protein resistance
- Molecular interactions with lipid bilayers
- Development of surface-specific analysis methods
- Spectroscopy on electroactive polymers
Background
Thomas Ederth has an MSc degree in Applied Physics and Electrical Engineering from the Linköping Institute of Technology. Efter a year of research at the Institute for Surface Chemistry, Stockholm (now a part of RISE), he continued to doctoral studies in Physical Chemistry at the Royal Institute of Technology (KTH), Stockholm, under the supervision of Prof Per Claesson. He graduated in 1999 with a thesis on intermolecular and surface forces. As a PostDoc at Oxford University, he was developing neutron scattering methods for characterization of foams and foam films, in the group of Dr Robert K Thomas. Dr Ederth spent a short time at Thin Film Electronics (Linköping) to work with polymer physics, but was recruited to the Sensor Science and Molecular Physics group at Linköping University in 2002, by Prof. Bo Liedberg. Thomas Ederth obtained a Docent degree in 2010, and 2012 he was appointed head of the Division of Molecular Physics, which was renamed the division of Biophysics and Bioengineering in 2020.
Teaching
Thomas Ederth is examiner and course responsible for the courses
- TFYA35 Molecular physics
- TFYA47 Surface and interfaces
Find more information about Thomas Ederth
ResearcherID: B-2417-2015
ORCID: 0000-0002-1639-5735
Selected publications
Biofouling and bioadhesion
W. Yandi, B. Nagy, A. Skallberg, K. Uvdal, R. Zimmermann, B. Liedberg, T. Ederth, "Polyampholytic poly(AEMA-co-SPMA) thin films and their potential for antifouling applications", ACS Applied Polymer Materials, 3(11), 5361–5372 (2021). DOI : 10.1021/acsapm.1c00383.
M. Lefevre, T. Ederth, T. Masai, R. Wattiez, P. Leclere, P. Flammang, E. Hennebert, "Disentangling the roles of functional domains in the aggregation and adsorption of the multimodular sea star adhesive protein Sfp1", Marine Biotechnology, 23(5), 724-735 (2021). DOI: 10.1007/s10126-021-10059-y.
J. Wunderer, B. Lengerer, R. Pjeta, P. Bertemes, L. Kremser, H. Lindner, T. Ederth, M. W. Hess, D. Stock, W. Salvenmoser, P. Ladurner, "A mechanism for temporary bioadhesion", PNAS, 116(10), 4297-4306 (2019). DOI: 10.1073/pnas.1814230116.
W. Yandi, S. Mieszkin, M. E. Callow, J. A. Callow, J. A. Finlay, B. Liedberg, T. Ederth, "Antialgal activity of poly(2-(dimethylamino)ethyl methacrylate) (PDMAEMA) brushes against the marine alga Ulva." Biofouling, 33(2), 169-183 (2017). DOI: 10.1080/08927014.2017.1281409.
W. Yandi, S. Mieszkin, P. Martin-Tanchereau, M. E. Callow, J. A. Callow, L. Tyson, B. Liedberg, T. Ederth, "Hydration and chain entanglement determines the optimum thickness of poly(HEMA-co-PEG10MA) brushes for effective resistance to settlement and adhesion of marine fouling organisms." ACS Applied Materials & Interfaces, 6(14), 11448–11458 (2014). DOI: 10.1021/am502084x.
Lipids and lipid bilayers
A.-M. Villamil Giraldo, I. Eriksson, S. Wennmalm, T. Fyrner, T. Ederth, K. Öllinger, "Interactions of the Lysosomotropic Detergent O-Methyl-Serine Dodecylamide Hydrochloride (MSDH) with Lipid Bilayer Membranes - Implications for Cell Toxicity", International Journal of Molecular Sciences, 21(9), 3136 (2020). DOI: 10.3390/ijms21093136.
A. M. Villamil Giraldo, T. Fyrner, S. Wennmalm, A. N. Parikh, K. Öllinger, T. Ederth, "Spontaneous vesiculation and pH-induced disassembly of a lysosomotropic detergent: impacts on lysosomotropism and lysosomal delivery." Langmuir, 32(50), 13566–13575 (2016). DOI: 10.1021/acs.langmuir.6b03458.
A. M. Villamil Giraldo, H. Appelqvist, T. Ederth, K. Öllinger, "Lysosomotropic agents: impact on lysosomal membrane permeabilization and cell death." Biochemical Society Transactions, 42(5), 1460–1464 (2014). DOI: 10.1042/BST20140145, Full text in DiVA.
P. Nygren, M. Lundqvist, B. Liedberg, B.-H. Jonsson, T. Ederth, "Secondary structure in de novo designed peptides induced by electrostatic interaction with a lipid bilayer membrane.", Langmuir 26(9), 6437–6448 (2010). DOI: 10.1021/la100027n, Full text in DiVA.
Self-assembled monolayers
T. Ederth, M. Lerm, B. Orihuela De Diaz, D. Rittschof, "The resistance of zwitterionic peptide monolayers to biofouling". Langmuir, 35(5), 1818 (2019). DOI: 10.1021/acs.langmuir.8b01625.
R. Nugraha, J. Finlay, S. Hill, T. Fyrner, W. Yandi, M. E. Callow, J. A. Callow, T. Ederth, "Antifouling properties of oligo(lactose)-based self-assembled monolayers." Biofouling. 31(1), 123-134 (2015). DOI: 10.1080/08927014.2014.1001841, Full text in DiVA.
A. Di Fino, L. Petrone, N. Aldred, T. Ederth, B. Liedberg, A.S. Clare, “Correlation between surface chemistry and settlement behaviour in barnacle cyprids (Balanus improvisus)” Biofouling, 30(2), 143-152 (2014). DOI: 10.1080/08927014.2013.852541, Full text in DiVA.
T. Fyrner, H.-S. Lee, A. Mangone, T. Ekblad, M. E. Pettitt, M. E. Callow, J. A. Callow, S. L. Conlan, R. Mutton, A. S. Clare, P. Konradsson, B. Liedberg, T. Ederth, “Saccharide-functionalized alkanethiols for fouling-resistant self-assembled monolayers: Synthesis, monolayer properties and anti-fouling behaviour.”, Langmuir, 27 (24), 15034–15047 (2011). DOI: 10.1021/la202774e.
T. Ederth, M. E. Pettitt, P. Nygren, C.-X. Du, T. Ekblad, Y. Zhou, M. Falk, M. E. Callow, J. A. Callow and B. Liedberg, “Interactions of zoospores of Ulva linza with arginine-rich oligopeptide monolayers.” Langmuir 25(16), 9375–9383 (2009). DOI: 10.1021/la900688g.
Vibrational spectroscopy at interfaces
M. J. Jafari, M. Golabi, T. Ederth, "Antimicrobial susceptibility testing using infrared attenuated total reflection (IR-ATR) spectroscopy to monitor metabolic activity", Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 304, 123384 (2023), DOI: 10.1016/j.saa.2023.123384.
M. J. Jafari, J. Liu, I. Engquist, T. Ederth, "Time-resolved chemical mapping in light-emitting electrochemical cells." ACS Applied Materials & Interfaces, 9(3), 2747–2757 (2017). DOI: 10.1021/acsami.6b14162.
U. Ail, M. J. Jafari, H. Wang, T. Ederth, M. Berggren, X. Crispin, "Thermoelectric Properties of Polymeric Mixed Conductors." Advanced Functional Materials, 26(34), 6288-6296 (2016). DOI: 10.1002/adfm.201601106.
L. Ouyang, C. Musumeci, M. J. Jafari, T. Ederth, O. Inganäs, "Imaging the phase separation between PEDOT and polyelectrolytes during processing of highly conductive PEDOT:PSS films." ACS Applied Materials & Interfaces7(35), 19764-19773 (2015). DOI: 10.1021/acsami.5b05439.
Neutron scattering
B. Nagy, T. Ekblad, G. Fragneto, T. Ederth, "Structure of self-initiated photopolymerized films: A comparison of models", Langmuir, 38(45), 14004-14015 (2022), DOI: 10.1021/acs.langmuir.2c02396.
C. Busch, B. Nagy, A. Stöcklin, P. Gutfreund, R. Dahint, T. Ederth, "A mobile set-up for simultaneous and in situ neutron reflectivity, infrared spectroscopy, and ellipsometry studies" Review of Scientific Instruments, 93, 114102 (2022), DOI: 10.1063/5.0118329.
B. Nagy, M. Campana, Y. N. Khaydukov, T. Ederth, "Structure and pH-induced swelling of polymer films prepared from sequentially grafted polyelectrolytes", Langmuir, 38(5), 1725–1737 (2022), DOI: 10.1021/acs.langmuir.1c02784.
T. Ederth, T. Ekblad, "Swelling of thin poly(ethylene glycol)-containing hydrogel films in water vapour - A neutron reflectivity study". Langmuir, 34(19), 5517–5526 (2018). DOI: 10.1021/acs.langmuir.8b00177.
T. Ederth, "Neutrons for scattering: What they are, where to get them, and how to deal with them". EPJ Web of Conferences, 188, 01002 (2018). DOI: 10.1051/epjconf/201818801002. (Tutorial book chapter)
