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Xiongyu Wu

Principal Research Engineer

Förste forskningsingenjör

Publications

2025

Steven R. Baginski, Karin Lindbom, Bryan Valencia Crespo, Ghidaa Bessa, Tobias Rautio, Xiongyu Wu, Johan Dahlén, Lorna A. Nisbet, Craig McKenzie, Henrik Green (2025) Structure-metabolism relationships of 4-pentenyl synthetic cannabinoid receptor agonists using in vitro human hepatocyte incubations and high-resolution mass spectrometry Archives of Toxicology (Article in journal) Continue to DOI
Henrik Green, Craig McKenzie, Elias Hamra, Tobias Rautio, Xiongyu Wu, Emma Juneskog, Rebecka Sandblom, Manuela Monti, Mattias Persson, Caitlyn Norman (2025) In vitro CB1 receptor activity of halogenated indazole synthetic cannabinoid receptor agonists Archives of Toxicology (Article in journal) Continue to DOI

2024

Xiongyu Wu, Hamid Shirani, Ruben Vidal, Bernardino Ghetti, Martin Ingelsson, Therése Klingstedt, Peter Nilsson (2024) Distinct Chemical Determinants are Essential for Achieving Ligands for Superior Optical Detection of Specific Amyloid-ß Deposits in Alzheimer's Disease ChemistryOpen, Vol. 13, Article e202400186 (Article in journal) Continue to DOI
Tobias Rautio, Matthew J. Connolly, Huiling Liu, Peter Konradsson, Henrik Green, Johan Dahlén, Xiongyu Wu (2024) Direct and selective alkylation of indazole-3-carboxylic acid for the preparation of synthetic cannabinoids and metabolites FORENSIC CHEMISTRY, Vol. 40, Article 100603 (Article in journal) Continue to DOI
Tobias Rautio, Robin Obrist, Lucas Krebs, Therése Klingstedt, Johan Dahlén, Xiongyu Wu, Henrik Green (2024) In vitro metabolism study of ADB-P-5Br-INACA and ADB-4en-P-5Br-INACA using human hepatocytes, liver microsomes, and in-house synthesized references Drug Testing and Analysis (Article in journal) Continue to DOI

News

Nina Ottosson in the lab.

A drug from resin to combat epileptic seizures

New molecules, developed by researchers at Linköping University, have promising properties as possible drugs against epilepsy. A study published in the journal Epilepsia shows that several of the molecules have antiseizure effects.
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New method to dampen nerve signals

Researchers at LiU have discovered a previously unknown molecular binding site that can influence electrical impulses in nerves. The discovery opens the possibility of designing new types of drugs against conditions such as epilepsy.
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Resin may provide medicine against epilepsy

Sticky resin from conifers contains substances that could relieve or cure epilepsy. Researchers at Linköping University have synthesized and tested 71 substances known as resin acids, of which twelve are prime candidates for new medicines.

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