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Xiongyu Wu

Principal Research Engineer

Förste forskningsingenjör

Presentation

Publications

2024

Tobias Rautio, Matthew J. Connolly, Huiling Liu, Peter Konradsson, Henrik Green, Johan Dahlén, Xiongyu Wu (2024) Direct and selective alkylation of indazole-3-carboxylic acid for the preparation of synthetic cannabinoids and metabolites FORENSIC CHEMISTRY, Vol. 40, Article 100603 (Article in journal) Continue to DOI
Tobias Rautio, Robin Obrist, Lucas Krebs, Therése Klingstedt, Johan Dahlén, Xiongyu Wu, Henrik Green (2024) In vitro metabolism study of ADB-P-5Br-INACA and ADB-4en-P-5Br-INACA using human hepatocytes, liver microsomes, and in-house synthesized references Drug Testing and Analysis (Article in journal) Continue to DOI
Karin Lindbom, Caitlyn Norman, Steven Baginski, Lucas Krebs, Darta Stalberga, Tobias Rautio, Xiongyu Wu, Robert Kronstrand, Henrik Green (2024) Human metabolism of the semi-synthetic cannabinoids hexahydrocannabinol, hexahydrocannabiphorol and their acetates using hepatocytes and urine samples Drug Testing and Analysis (Article in journal) Continue to DOI

2023

Afshan Begum, Jun Zhang, Dean Derbyshire, Xiongyu Wu, Peter Konradsson, Per Hammarström, Eleonore von Castelmur (2023) Transthyretin Binding Mode Dichotomy of Fluorescent trans-Stilbene Ligands ACS Chemical Neuroscience, Vol. 14, p. 820-828 (Article in journal) Continue to DOI
Steven R. Baginski, Tobias Rautio, Lorna A. Nisbet, Karin Lindbom, Xiongyu Wu, Johan Dahlén, Craig Mckenzie, Henrik Green (2023) The metabolic profile of the synthetic cannabinoid receptor agonist ADB-HEXINACA using human hepatocytes, LC-QTOF-MS and synthesized reference standards Journal of Analytical Toxicology, Vol. 47, p. 826-834 (Article in journal) Continue to DOI

News

Nina Ottosson in the lab.

A drug from resin to combat epileptic seizures

New molecules, developed by researchers at Linköping University, have promising properties as possible drugs against epilepsy. A study published in the journal Epilepsia shows that several of the molecules have antiseizure effects.

New method to dampen nerve signals

Researchers at LiU have discovered a previously unknown molecular binding site that can influence electrical impulses in nerves. The discovery opens the possibility of designing new types of drugs against conditions such as epilepsy.

Resin may provide medicine against epilepsy

Sticky resin from conifers contains substances that could relieve or cure epilepsy. Researchers at Linköping University have synthesized and tested 71 substances known as resin acids, of which twelve are prime candidates for new medicines.

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