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Neuronal and molecular mechanisms of compulsive drug use
The purpose of the current neuroscience research is to understand the molecular mechanisms that promote transition to drug addiction, with a main focus on alcohol use disorders.
Neural circuits underlying decision-making in alcohol addiction
Using a model of compulsive alcohol self-administration model in rats, we have found that a subpopulation of animals continues to self-administer despite an aversive consequence.
Epigenetic reprogramming as a mechanism in anxiety and alcohol use disorder (AUD).
This project aims to identify long-term neuroadaptations involved in alcohol addiction and anxiety disorders.