Publications from the Neuroengineering group at the Department of Biomedical Engineering (IMT).

En bild på neuroteknikgruppens avhandlingar

Articles

2024

Tapper S, Tisell A, Hillman J, Wårdell K, Method for Detection of Cerebral Blood Flow in Neurointensive Care Using Longitudinal Arterial Spin Labeling MRIPLoS ONE 19(11): e0314056, 2024, https://doi.org/10.1371/journal.pone.0314056

Klint K, Richter J, Milos P, Hallbeck M, Wårdell K, In-situ optical feedback in brain tumor biopsy – a multiparametric analysis Neuro-Oncology Advances, 2024 https://academic.oup.com/noa/advance-article/doi/10.1093/noajnl/vdae175/7839436

Wårdell K, Richter J, Zsigmond P, Cerebral Microcirculation: Progress and Outlook of Laser Doppler Flowmetry in Neurosurgery and Neurointensive CareFirst published: 28 September 2024, REVIEW, https://doi.org/10.1111/micc.12884

Vogel D, Nordin T, Feiler S, Wårdell K, Coste J, Lemaire JJ, Hemm S, Probabilistic stimulation mapping from intra-operative thalamic deep brain stimulation data in essential tremorNeural Eng. 21 (2024) 036017, https://doi.org/10.1088/1741-2552/ad4742

2023

Klint, E.; Richter, J.; Wårdell, K. Combined Use of Frameless Neuronavigation and In Situ Optical Guidance in Brain Tumor Needle Biopsies. Brain Sci. 2023, 13, 809. https://doi.org/10.3390/brainsci13050809

Nordin T, Blomstedt P, Hemm S and Wårdell K, How Sample Size Impacts Probabilistic Stimulation Maps in Deep Brain Stimulation, Brain Sci. 2023, 13, 756. https://doi.org/10.3390/brainsci13050756

Wårdell K, Klint E, Milos P, Richter J, One-Insertion Stereotactic Brain Biopsy using In-Vivo Optical Guidance – A Case Study, Operative Neurosurgery 00:1–7, 2023, https://doi.org/10.1227/ons.0000000000000722

Milos P, Haj-Hosseini N, Hillman J, Wårdell K, Fluorescence 5-ALA in randomly selected pediatric brain tumors assessed by spectroscopy and surgical microscope. doi: 10.1007/s00701-022-05360-1 Acta Neurochirurgica, 165:71-81, 2023

2022

Wahl J, Klint E, Hallbeck M, Hillman J, Wårdell K, and Ramser K, Impact of preprocessing methods on the Raman spectra of brain tissue, Biomedical Optics Express, Vol. 13, Issue 12, pp. 6763-6777, (2022), https://doi.org/10.1364/BOE.476507

Mauritzon S, Ginstman F, Hillman J, Wårdell K, Analysis of Laser Doppler Flowmetry Long-Term Recordings for Investigation of Cerebral Microcirculation during Neurointensive Care,  Frontiers in Neuroscience, section Neural Technology , 1030805 , p 1-11, 2022. doi: 10.3389/fnins.2022.1030805

Nordin T, Vogel D, Österlund E, Johansson J, Blomstedt P, Fytagoridis A, Hemm SWårdell K Probabilistic maps for deep brain stimulation - Impact of methodological differences. Brain Stimul. 2022 Aug 18;15(5):1139-1152. doi: 10.1016/j.brs.2022.08.010. Online ahead of print. PMID: 35987327

Johansson JD, Wårdell K DBSim and ELMA - Freeware for Simulations of Deep Brain Stimulation. Annu Int Conf IEEE Eng Med Biol Soc. 2022 Jul;2022:1719-1724. doi: 10.1109/EMBC48229.2022.9871821. PMID: 36086324

Wårdell K, Nordin T, Vogel D,Zsigmond P, Westin C-F, Hariz M and Hemm S (2022) Deep Brain Stimulation: Emerging Tools for Simulation, Data Analysis, and Visualization. Front. Neurosci. 16:834026. doi: 10.3389/fnins.2022.834026

2021

Klint E, Mauritzon S, Ragnemalm B, Richter J, Wårdell K, FluoRa - a System for Combined Fluorescence and Microcirculation Measurements in Brain Tumor Surgery. 
Annu Int Conf IEEE Eng Med Biol Soc. Nov;2021:1512-1515. doi: 10.1109/EMBC46164.2021.9629801. PMID: 34891572

Naesström M, Johansson J, Hariz M, Bodlund O, Wårdell K, Blomstedt P. Distribution of electric field in patients with obsessive compulsive disorder treated with deep brain stimulation of the bed nucleus of stria terminalis. Acta Neurochir (Wien). 2022 Jan;164(1):193-202. doi: 10.1007/s00701-021-04991-0. Epub 2021 Oct 15. PMID: 34652518 Free article.

Richter J, Haj-Hosseini N, Milos P, Hallbeck M, Wårdell K, Optical Brain Biopsy with a Fluorescence and Vessel Tracing Probe. Oper Neurosurg (Hagerstown). 2021 Sep 15;21(4):217-224. doi: 10.1093/ons/opab216. PMID: 34192763 Free PMC article.

Göransson N, Johansson JD, Wårdell K, Zsigmond P, Postoperative Lead Movement after Deep Brain Stimulation Surgery and the Change of Stimulation Volume. Stereotact Funct Neurosurg. 2021;99(3):221-229. doi: 10.1159/000511406. Epub 2020 Dec 16. PMID: 33326986 Free article.

Alonso F, Zsigmond P, Wårdell K. Influence of Virchow-Robin spaces on the electric field distribution in subthalamic nucleus deep brain stimulation. Clin Neurol Neurosurg. 2021 May;204:106596. doi: 10.1016/j.clineuro.2021.106596. Epub 2021 Mar 9. PMID: 33813373 Free article.

Stenmark Persson R, Nordin T, Hariz GM, Wårdell K, Forsgren L, Hariz M, Blomstedt P, Deep Brain Stimulation of Caudal Zona Incerta for Parkinson's Disease: One-Year Follow-Up and Electric Field Simulations. Neuromodulation. 2021 Jul 27. doi: 10.1111/ner.13500. Online ahead of print.

Johansson JD, Zsigmond, Comparison between patient-specific deep brain stimulation simulations and commercial system SureTune3. Biomed Phys Eng Express. 2021 Jul 1;7(5). doi: 10.1088/2057-1976/ac0dcd.

Nordin T., Wårdell K., Johansson J.D. (2021) The Effect of Anisotropy on the Impedance and Electric Field Distribution in Deep Brain Stimulation. In: Jarm T., Cvetkoska A., Mahnič-Kalamiza S., Miklavcic D. (eds) 8th European Medical and Biological Engineering Conference. EMBEC 2020. IFMBE Proceedings, vol 80. Springer, Cham. 2021.

Vogel D., Wårdell K., Coste J., Lemaire JJ., Hemm S. Atlas Optimization for Deep Brain Stimulation. In: Jarm T., Cvetkoska A., Mahnič-Kalamiza S., Miklavcic D. (eds) 8th European Medical and Biological Engineering Conference. EMBEC 2020. IFMBE Proceedings, vol 80. Springer, Cham. 2021. 

2020

Vogel D, Shah A, Coste J, Lemaire JJ, Wårdell K, Hemm S, Anatomical brain structures normalization for deep brain stimulation in movement disordersNeuroimage: Clinical, Vol 27, 2020, 102271.

Shah AA, Vogel D, Alonso A, Lemaire JJ, Pison D, Coste J, Wårdell K, Schkommodau E and Hemm S Stimulation Maps: Visualization of results of quantitative intraoperative testing for deep brain stimulation surgeryMed Biol Eng Comput, Jan 30.

Zsigmond P & Wårdell K, Optical Measurements during Asleep Deep Brain Stimulation Surgery along Vim-Zi Trajectories, Stereotac Func Neurosurg, Feb 20:1-7. 

2019

Teresa Nordin, Peter Zsigmond, Sonia Pujol, Carl-Fredrik Westin, Karin Wårdell, White matter tracing combined with electric field simulation - a patient-specific approach for deep brain stimulationNeuroimage: Clinical, 24, 2019.

Pham T, Eklund A, Wårdell K, Salerud G, Classification of Short Time Series in Early Parkinson's Disease with Deep Learning of Fuzzy Recurrence Plots, IEEE/CAA Journal of Automatica Sinica, Accepted 2019.

Johansson JD, Alonso F, Wårdell K, Patient-Specific Simulations of Deep Brain Stimulation Electric Field with Aid of In-house Software ELMA41st IEEE-EMBC, pp 5212-5216, 2019.

Wårdell K, Hemm-Ode S, Zsigmond P, A System for Combined Laser Doppler Flowmetry and Microelectrode Recording during Deep Brain Stimulation Implantation41st IEEE-EMBC, pp 3759-3761, 2019.

Latorre MA and Wårdell K, A Comparison between Single and Double Cable Neuron Models Applicable to Deep Brain StimulationBiomedical Physics & Engineering Express, 5(2),1-13, 2019.

Michaela Mainz, David Black, Neda Haj-Hosseini, Auditory and Visual User Interface for Optical Guidance During Stereotactic Brain Tumor Biopsies, Accepted, IEEE EMBC conference, 2019.

2018

Fabiola Alonso, Models and Simulations of the Electric Field in Deep Brain Stimulation: Comparison of Lead Designs, Operating Modes and Tissue ConductivityLinköping Studies in Science and Technology, Doctorate Thesis No. 1945, 2018, ISSN 0345-7524.

Shah AA, Alonso F, Vogel D, Wårdell K, Coste J, Lemaire JJ, Pison D, Hemm S. Analysis of adverse effects of stimulation during DBS surgery by patient-specific FEM simulations, Conf Proc IEEE Eng Med Biol Soc. 2018 Jul;2018:2222-2225.

Johansson JD, Alonso F, Wårdell K, Modelling Details for Electric Field Simulations of Deep Brain Stimulation. In: Lhotska L, Sukupova L, Lackovic I, Ibbott G (eds). IFMBE Proceedings Springer, pp 645-648, vol 68/1, 2018.

Haj-Hosseini N; Richter J; Kobayashi Frisk L; Milos P; Hallbeck M; Wårdell K, Fluorescence Guidance for Brain Tumour Biopsies,OSA Biophotonics Conference, Florida, USA, 2018.

Wårdell K, Zsigmond P, Richter J, Hemm S Optical Guidance System for Deep Brain Stimulation Surgery – from Experimental Studies to Clinical Use, OSA, Biophotonics Conference, Florida, USA, 2018.

Haj-Hosseini N., Richter J, Milos P., Hallbeck M., Wårdell K 5-ALA fluorescence and laser Doppler flowmetry for guidance in a stereotactic brain tumor biopsy Biomedical Optics Express, 9(5), 2018.

Black D, Hahn H, Kikinis R, Wårdell K, Haj-Hosseini N. Auditory display for fluorescence-guided open brain tumor surgeryInternational Journal of Computer Assisted Radiology and Surgery, 13(1), 2018.

Alonso F., Vogel D., Johansson J., Wårdell K, Hemm-Ode S. Electric Field Comparison between Microelectrode Recording and Deep Brain Stimulation Systems-A Simulation Study Brain Sci., 8(2), 2018.

Zsigmond P., Hemm-Ode S., Wårdell K. Optical Measurements during Deep Brain Stimulation Lead Implantation: Safety AspectsStereotact Funct Neurosurg., 95(6):392-399, 2018.

Rejmstad P, Haj-Hosseini N, Åneman O, Wårdell K. Optical monitoring of cerebral microcirculation in neurointensive careMedical & Biological Engineering & Computing, Vol 56 (7), pp 1201–1210, 2018.

2017

Johan Richter, Fluorescence Guided Resection of Brain Tumors: Evaluation of a Hand-held Spectroscopic ProbeLinköping University Medical Dissertations, Doctorate Thesis No. 1581, 2017, ISSN 0345-0082.

Malcolm Latorre, The Physical Axon: Modeling, Simulation and Electrode EvaluationLinköping studies in Science and Technology, Doctorate Thesis No. 1847, 2017, ISBN 0345-7524.

Peter Rejmstad, Optical Monitoring of Cerebral MicrocirculationLinköping studies in Science and Technology, Doctorate Thesis No. 1807, 2017, ISBN 0345-7524.

Akbarian-Tefaghi L, Harith A, Johansson J, Zrinzo L, Zinovia K, Limousin P, Eileen J, Hariz M, Wårdell K, Foltynie T, Refining the Deep Brain Stimulation Target within the Limbic Globus Pallidus Internus for Tourette SyndromeStereotactic and Functional Neurosurgery, Vol. 95, nr 4, pp 251-258, 2017.

Richter J, Haj-Hosseini N, Hallbeck M, Wårdell K, Combination of Hand-Held Probe and Microscopy for Fluorescence Guided Surgery in the Brain Tumor Marginal ZoneJournal of Photodiagnosis and Photodynamic Therapy, Vol. 18, pp 185-192, 2017.

Rejmstad P, Zsigmond P, Wårdell K, Oxygen saturation estimation in brain tissue using diffuse reflectance spectroscopy along stereotactic trajectoriesOptics Express. vol 25, no. 7, pp8192:8201, 2017.

2016

Hemm-Ode S, Pison D, Alonso F, Shah A, Coste J, Lemaire JJ, Wårdell K, Patient-specific electric field simulations and acceleration measurements for objective analysis of intraoperative stimulation test in the thalamusFront. Hum. Neurosci. 25 November 2016, doi: 10.3389/fnhum.2016.00577, 2016.

Wårdell K, Optical Techniques for Navigation during in Stereotactic NeurosurgerySensors and Materials, Vol. 28, No. 10 (2016) 1105–1116, doi: 10.18494/SAM.2016.1272, 2016.

Alonso F, Latorre M A, Göransson N, Zsigmond P and Wårdell K, Investigation into Deep Brain Stimulation Lead Designs: A Patient-Specific Simulation StudyBrain Sciences, 6(3), 39; doi:10.3390/brainsci6030039, 2016.

Rejmstad P, Johansson JD, Haj-Hosseini N, Wårdell K, A method for monitoring of oxygen saturation changes in brain tissue using diffuse reflectance spectroscopyJournal of Biophotonics, DOI: 10.1002/jbio.201500334, 2016.

Wårdell K, Hemm-Ode S, Rejmstad P, Zsigmond P, High-Resolution Laser Doppler Measurements of Microcirculation in the Deep Brain Structures: A Method for Potential Vessel TrackingStereotact Funct Neurosurg 2016;94:1-9 (DOI:10.1159/000442894), 2016.

2015

Latorre M, Chan A.D.C, Wårdell K, A physical axon potential generator: design, implementation and evaluationFrontiers in Neuroscience, 20 October 2015, 9:371. doi: 10.3389/fnins.2015.00371, 2015.

Malcolm Latorre, Action Potential Generator and Electrode TestingLinköping studies in Science and Technology, Licentiate Thesis No. 1725, 2015, ISBN 978-91-7685-974-2.

Alonso F, Hemm-Ode S, Wårdell K, Influence on Deep Brain Stimulation from Lead Design, Operating Mode and Tissue Impedance Changes – A Simulation StudyBrain Disorders and Therapy, June 2015, DOI: 10.4172/2168-975X.1000169, 2015.

Rejmstad P, Åkesson G, Åneman O, Wårdell K, A laser Doppler system for monitoring cerebral microcirculation: implementation and evaluation during neurosurgeryMedical & Biological Engineering & Computing, 2016, 54:123–131, DOI 10.1007/s11517-015-1332-5.

Haj-Hosseini N, Richter JCO, Hallbeck M, Wårdell K, Low dose 5-aminolevulinic acid: Implications in spectroscopic measurements during brain tumor surgeryPhotodiagnosis and Photodynamic Therapy, Volume 12, Issue 2, June 2015, Pages 209–214, DOI:10.1016/j.pdpdt.2015.03.004, 2015. DiVA link

2014

Åström M, Diczfalusy E, Martens H, Wårdell K, Relationship between Neural Activation and Electric Field Distribution during Deep Brain StimulationIEEE Trans Biomed Eng. 2014 Oct 23. [Epub ahead of print] PMID:25350910, 2014.

Wårdell K, Kefalopoulou Z, Diczfalusy E, Andersson M, Aström M, Limousin P, Zrinzo L, Hariz M, Deep Brain Stimulation of the Pallidum Internum for Gilles de la Tourette Syndrome: A Patient-Specific Model-Based Simulation Study of the Electric FieldNeuromodulation. 2014 Oct 6. DOI: 10.1111/ner.12248., 2014.

Zsigmond P, Nord M, Kullman A, Diczfalusy E, Wårdell K and Dizdar N, Neurotransmitter levels in basal ganglia during levodopa and Deep Brain Stimulation treatment in Parkinson´s DiseaseNeurology and Clinical Neuroscience 07/2014; DOI: 10.1111/ncn3.109, 2014.

Haj-Hosseini N., Kistler B., Wårdell K., Development and characterization of brain tumor mimicking fluorescence phantomSPIE Photonics West, Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue VI, 2014.

Haj-Hosseini N., Behm P., Shabo I., Wårdell K., Fluorescence spectroscopy using indocyanine green for lymph node mappingSPIE Photonics West, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XII, 2014.

2013

Wårdell K, Zrinzo Z, Hariz M, Andersson M, Patient-Specific Brain Modelling for Deep Brain Stimulation Simulation, The 2013 6th International IEEE EMBS Conference on Neural Engineering proceedings page 148-151.

Wårdell K, Haj-Hosseini N and Hemm S, Comparison between Optical and MRI Trajectories in Stereotactic NeurosurgeryIFMBE Proceeding, Vol. 41, p. 49-51, 2013.

Diczfalusy E, Andersson M, Wårdell K, A diffusion tensor based finite element model of microdialysis in the deep brainComputer Methods in Biomechanics and Biomedical Engineering 2013, DOI:10.1080/10255842.2013.789103.

2012

Wardell K, Zsigmond P, Richter J, Hemm S Relation Between Laser Doppler Signals and Anatomy During Deep Brain Stimulation Electrode Implantation Towards Vim and STNNeurosurgery. 2012 Nov 27. [Epub ahead of print], PMID:23190636 DiVA link

Rejmstad P; Akesson G; Hillman J; Wardell K, A laser Doppler system for monitoring of intracerebral microcirculationProceedings of IEEE EMBS: 1988 - 1991, 2012. DiVA link

Diczfalusy E; Dizdar N; Zsigmond P; Kullman A; Loyd D; Wardell K Simulations and visualizations for interpretation of brain microdialysis data during deep brain stimulationProceedings of IEEE EMBS: 6438 - 6441, 2012. DiVA link

Hirbayashi H, Hariz MI, Wårdell K, Blomstedt P Impact of Parameters of Radiofrequency Coagulation on Volume of Stereotactic Lesion in Pallidotomy and ThalamotomyStereotact and Funct Neurosurg, 90(5):307-315, 2012. DiVA link

Elin Diczfalusy Modeling and Simulation of Microdialysis in the Deep Brain StructuresLinköping studies in Science and Technology, Licentiate Thesis No. 1549, 2012, ISBN 978-91-7519-805-7.

Haj-Hosseini N Fluorescence Spectroscopy for Quantitative Demarcation of Glioblastoma Using 5-Aminolevulinic AcidLinköping Studies in Science and Technology, Dissertation No. 1463, LiU-Tryck, Linköping 2012, ISBN 978-91-7519-845-3.

Johansson JD, Wårdell K Intracerebral quantitative chromophore estimation from reflectance spectra captured during deep brain stimulation implantation, J Biophotonics, Aug 2012. DiVA link

Fytagoridis A, Åström M, Wårdell K, Blomstedt P Stimulation-induced side effects in the posterior subthalamic area: Distribution, characteristics and visualization, Clinical Neurology and Neurosurgery, In press, 2012. DiVA link

Åström M, Lemaire JJ and Wårdell K Influence of heterogeneous and anisotropic tissue conductivity on electric field distribution in deep brain stimulation, Med Biol Eng Comput, 50(1):23-32, 2012. DiVA link

2011

Diczfalusy E, Zsigmond P, Dizdar N, Kullman A, Loyd D, Wårdell K A model for simulation and patient-specific visualisation of the tissue model of influence during microdialysisMed Biol Eng Comput, 49(12):1459-1469, 2011. DiVA link

Wårdell K, Diczfalusy E, Åström M Patient-Specific Modeling and Simulation of Deep Brain StimulationIn: Studies in Mechanobiology, Tissue Engineering and Biomaterials. Springer-Verlag Berlin Heidelberg 2011. DiVA link

Åström M Modelling, Simulation, and Visualization of Deep Brain Stimulation, Linköping Studies in Science and Technology, Dissertation No. 1384, LiU-Tryck, Linköping 2011, ISBN 978-91-7393-114-4.

Brydegaard M, Haj-Hosseini N, Wårdell K, Andersson-Engels S Photobleaching-Insensitive Fluorescence Diagnostics in Skin and Brain TissueIEEE PHOTONICS JOURNAL, 3(3): 407-421, 2011. DiVA link

Haj-Hosseini N, Lowndes S, Salerud G, Wårdell K Blood interference in fiber-optical based fluorescence guided resection of glioma using 5-aminolevulinic acidProc. SPIE 7883, 78833R (2011). DiVA link

Richter JCO, Haj-Hosseini N, Andersson-Engel, S, Wårdell K Fluorescence spectroscopy measurements in ultrasonic navigated resection of malignant brain tumorsLasers Surg Med, 43(1): 8-14, 2011. DiVA link

2010 and before

J. D. Johansson Spectroscopic method for determination of the absorption coefficient in brain tissue, Journal of Biomedical Optics, Biomed Opt. 2010 Sep-Oct;15(5):057005. DiVA link

Hemm S, Wårdell K Stereotactic implantation of deep brain stimulation electrodes: a review of technical systems, methods and emerging toolsMed Biol Eng Comput 48(7):611-24, 2010. DiVA link

Åström M, Tripoliti E, Hariz MI, Zrinzo LU, Martinez-Torre I, Limousin P, Wårdell K Patient-specific model-based investigation of speech intelligibility and movement during deep brain stimulationStereotact Funct Neurosurg 2010;88:224-233 DiVA link

Haj-Hosseini N, Richter J, Andersson-Engels S, Wårdell K Optical touch pointer for fluorescence guided brain tumour resection using 5-aminolevulinicLasers Surg Med, Jan;42(1):9-14, 2010. DiVA link

Nord M, Zsigmond P, Kullman A, Årstrand K and Dizdar N The effect of peripheral enzyme inhibitors on Levodopa concentrations in blood and CSFMov Disord.,15;25(3):363-7, 2010. DiVA link

Wårdell K, Johansson J, Richter J, Blomstedt P Optical measurments for guidance during deep brain stimulation surgery, Medical Physics and Biomedical Engineering, World Congress, München, IFMBE Proceeding, Vol. 25/IX, 516-517, 2009. DiVA link

Åström M, Tripoliti E, Zrinzo LU, Martinez-Torre I, Limousin P, Hariz MI, Wårdell K Patient-specific models and simulations of deep brain stimulation for postoperative follow-upMedical Physics and Biomedical Engineering, World Congress, München, IFMBE Proceedings, 25/IX, 331-334, 2009. DiVA link

Johannes D. Johansson, Ingemar Fredriksson, Karin Wårdell and Ola Eriksson Simulation of reflected light intensity changes during navigation and radio-frequency lesioning in the brainJournal of Biomedical Optics 2009,vol. 14, issue 4, pp. 044040 1-7, 2009 DiVA link

Johansson J D, Blomstedt P, Haj-Hosseini N, Bergenheim A T, Eriksson O, and Wårdell K Combined diffuse light reflectance and electric impedance measurements for navigation aid in deep brain surgery Stereotact Funct Neurosurg 87 105-13 , 2009 DiVA link

Johansson J D Impact of Tissue Characteristics on Radio-Frequency Lesioning and Navigation in the Brain: Simulation, experimental and clinical studiesLinköping Studies in Science and Technology, Dissertation No. 1230, LiU-Tryck, Linköping 2009, ISBN 978-91-7393-723-8.

Haj-Hosseini N, Richter J, Andersson-Engels S, Wårdell K Photobleaching behavior of protoporphyrin IX during 5-aminolevulinic acid marked glioblastoma detectionProc. of SPIE Vol. 7161, 716131, 2009. DiVA link

Johansson J D, Blomstedt P, Haj-Hosseini N, Bergenheim A T, Eriksson O, and Wårdell K Combined diffuse light reflectance and electric impedance measurements for navigation aid in deep brain surgeryStereotact Funct Neurosurg 87 105-13, 2009 DiVA link

Astrom M, Zrinzo LU, Tisch S, Tripoliti E, Hariz MI, Wardell K Method for patient-specific finite element modeling and simulation of deep brain stimulationMed Biol Eng Comput, 2008. DiVA link

Haj-Hosseini N, Andersson-Engels S, Wårdell K Evaluation of a fiber-optic based pulsed laser system for fluorescence spectroscopyNBC-IFMBE Proceedings 20, 363-366, 2008. DiVA link

Johansson J, Zerbinati A, Wårdell K Diffuse Reflectance Spectroscopy During Experimental Radio Frequency AblationNBC-IFMBE Proceedings 20, 371-274, 2008. DiVA link

Antonsson J, Eriksson O, Blomstedt P, Bergenheim AT, Hariz MI, Richter J, Zsigmond P, Wårdell K Diffuse reflectance spectroscopy measurements for tissue type discrimination during deep brain stimulationJ Neural, 5(2): 185-190 2008. Eng. 5 1-6, 2008. DiVA link

Ilias MA, Richter J, Westermark F, Brantmark M, Andersson-Engels S and Wårdell K Evaluation of a Fiber-Optic Fluorescence Spectroscopy System to Assist Neurosurgical Tumor ResectionsProc. SPIE-OSA 6631, 663110W, 1-7, 2007. DiVA link

Wårdell K, Blomstedt P, Richter J, Antonsson J, Eriksson O, Zsigmond P, Bergenheim AT, Hariz MI Intracerebral microvascular measurements during deep brain stimulation implantation using laser Doppler perfusion monitoringStereotac Func Neurosurg;85:279-286, 2007. DiVA link

Wårdell K, Fors C, Antonsson J, Eriksson O. Wårdell A laser Doppler system for intracerebral measurements during stereotactic neurosurgery. Conf Proc IEEE Eng Med Biol Soc. 2007;2007:4083-6.

PhD Theses

Most recent PhD theses

All PhD theses

Teresa Nordin, Computational Models in Deep Brain Stimulation: Patient Specific Simulations, Tractography, and Group Analysis, Linköping Studies in Science and Technology Doctorate Thesis No. 2268, 2023

Dorian Vogel,Deep Brain Stimulation Atlases in Movement Disorders: from Patient-Specific to Group Analysis, Linköping Studies in Science and Technology Doctorate Thesis No. 2215, 2022

Fabiola Alonso,Models and Simulations of the Electric Field in Deep Brain Stimulation: Comparison of Lead Designs, Operating Modes and Tissue Conductivity,Linköping Studies in Science and Technology Dissertations No. 1945, 2018.

Johan Richter,Fluorescence Guided Resection of Brain Tumors: Evaluation of a Hand-held Spectroscopic Probe, Linköping University Medical Dissertation No. 1581, 2017.

Malcolm Latorre,The Physical Axon: Modeling, Simulation and Electrode Evaluation,Linköping Studies in Science and Technology Dissertations No1847, 2017.

Peter Rejmstad,Optical Monitoring of Cerebral Microcirculation,Linköping Studies in Science and Technology Dissertations No.1807, 2017.

Elin Diczfalusy,Modeling and Simulation of Microdialysis in the Deep Brain Structures, Lic. Eng. Thesis No. 1549, 2012.

Neda Haj-Hosseini,"Fluorescence Spectroscopy for Quantitative Demarcation of Glioblastoma Using 5-Aminolevulinic Acid, Linköping Studies in Science and Technology Dissertations No.1463, 2012.

Mattias Åström,Modelling, Simulation, and Visualization of Deep Brain Stimulation, Linköping Studies in Science and Technology Dissertations No. 1384, 2011.

Johannes Johansson,Impact of Tissue Characteristics on Radio-Frequency Lesioning and Navigation in the Brain: Simulation, experimental and clinical studies, Linköping Studies in Science and Technology Dissertations No.1230, 2009.

Magnus Falk,Towards a broader use of phototesting – in research, clinical practice and skin cancer prevention,Linköping University Medical Dissertation No. 1024, 2007.

Carina Fors,Evaluation of a laser Doppler System for Myocardial Perfusion Monitoring, Lic. Eng. Thesis No. 1326, 2007.

Johan Antonsson,Optical methods for intracerebral measurements during stereotactic and functional neurosurgery – experimental studies, Linköping Studies in Science and Technology Dissertations No.1070, 2007.

Daniel Karlsson,Movement artifacts reduction in laser Doppler blood flowmetry – myocardial perfusion applications”, Linköping Studies in Science and Technology Dissertation No. 935, 2005.

Michail Ilias,Single exposure phototesting and assessment of pigmented skin lesions – Quantitative methods in terms of blood perfusion estimates,Linköping Studies in Science and Technology Dissertation No. 935, 2003.

Ola Eriksson, Characterisation and modelling of radiofrequency lesioning in neurosurgery”, Linköping Studies in Science and Technology Dissertation No. 693, 2001.

Karin Wårdell, Laser Doppler Perfusion Imager – Methodology and Skin Applications, Studies in Science and Technology,Linköping Studies in Science and Technology Dissertation No.329, 1994.

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