Photo of Diana Atanasova

Diana Atanasova

Presentation

My field of research is bone and mineral metabolism, including both experimental and clinical studies, with bone alkaline phosphatase as the main focus. Bone alkaline phosphatase is a biomarker of skeletal mineralization and vascular calcification.

In experimental studies, I am studying the structure and function of bone alkaline phosphatase and its role as a biomarker and treatment target of vascular calcification. This includes studying cellular models for expression, mineralization and investigation of protein structure and function with different methods for protein analysis. This is the main focus of my PhD-studies.

The clinical studies, performed in collaboration with national and international investigators, includes bone and mineral disorders, such as osteoporosis and vascular calcification in chronic kidney disease. I am involved in analyzing bone turnover markers with biochemical and immunoassays.

Apart from my involvement in experimental and clinical research at the Division of Clinical Chemistry and Pharmacology, I am also a member of the research school Forum Scientium.


Publications

Master thesis

2024

Per Magnusson, Maria Saaf, Anna Martling, Annika Svanstrom Rojvall, Diana Atanasova, Franciszek Wilamowski, Angelique Floter Radestad, Christian Buchli, Josefin Segelman (2024) Bone turnover biomarkers reflect radiation-induced bone injuries in women with non-metastatic rectal cancer JBMR Plus, Vol. 8, Article ziae087 (Article in journal) Continue to DOI
Natalja Jackmann, Jan Gustafsson, Pauliina Utriainen, Per Magnusson, Arja Harila, Diana Atanasova, Carina Rinaldo, Per Frisk, Outi Makitie (2024) Demographic and disease-related factors impact bone turnover and vitamin D in children with hemato-oncological diseases JBMR Plus, Vol. 8, Article ziae017 (Article in journal) Continue to DOI
Diana Atanasova, Ekaterina Mirgorodskaya, Lavanya Moparthi, Stefan Koch, Mathias Haarhaus, Sonoko Narisawa, José Luis Millán, Eva Landberg, Per Magnusson (2024) Glycoproteomic profile of human tissue-nonspecific alkaline phosphatase expressed in osteoblasts JBMR Plus, Vol. 8, Article ziae006 (Article in journal) Continue to DOI

2022

Ahmed Omran, Diana Atanasova, Filip Landgren, Per Magnusson (2022) Sclerostin: From Molecule to Clinical Biomarker International Journal of Molecular Sciences, Vol. 23, Article 4751 (Article, review/survey) Continue to DOI

2017

Wing Cheung Mak, B. Magne, Kitt Cheung, Diana Atanasova, May Griffith (2017) Thermo-rheological responsive microcapsules for time-dependent controlled release of human mesenchymal stromal cells Biomaterials Science, Vol. 5, p. 2241-2250 (Article in journal) Continue to DOI

Research

Education

MSc in Medical Biology

PhD-student, Clinical Chemistry

Forum Scientium member

Bachelor´s degree in Medical Biology, Linköping University

Master´s degree in Experimental and Medical Biosciences, Linköping University

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Forum Scientium Graduate School

Graduate school Forum Scientium, a bridge between medicine, natural sciences and engineering, stimulates creativity and a common use of ideas, knowledge, and equipment.