My research focuses on how simple clinical tests can be used to enable early identification of circulatory compromise in patients, and how objective measurement methods can strengthen assessments that today are largely based on clinical experience. I work within clinical and experimental medicine, with a particular focus on the capillary refill test as a method for assessing circulation and perfusion in emergency care settings. My research investigates the reproducibility and reliability of the test, both in repeated measurements and between different observers, as well as how its outcomes are affected under conditions of hemodynamic stress. A central component of this work is to study how capillary refill time changes in a controlled model of blood loss, and how these changes relate to microcirculation, perfusion, and tissue oxygenation. By applying bio-optical imaging techniques for the objective quantification of capillary refill time, this research contributes to a deeper understanding of the physiological basis and clinical relevance of the test. The overall aim is to develop more reliable methods for circulatory assessment that can be applied in acute and resource-constrained healthcare settings.
Frida Meyer
Doktor. My research focuses on the assessment of circulatory shock in acutely ill and injured patients using both simple clinical assessment methods and novel optical measurement techniques.
Publications
2026
Under Pressure: Microcirculatory Dynamics and Capillary Refill Assessment in Provocation and Hemodynamic Stress
(Doctoral thesis, comprehensive summary)
https://dx.doi.org/10.3384/9789181183160
2025
Can we trust naked eye assessments of the capillary refill test in children? An experimental study
BMC Emergency Medicine, Vol. 25, Article 48
(Article in journal)
https://dx.doi.org/10.1186/s12873-025-01204-0
Capillary refill time paradoxically decreases in a blood loss shock model
Intensive Care Medicine Experimental, Vol. 13, Article 8
(Article in journal)
https://dx.doi.org/10.1186/s40635-025-00714-2
Definition and developmental goals for Nordic emergency medicine
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, Vol. 33, Article 7
(Article in journal)
https://dx.doi.org/10.1186/s13049-025-01319-0
2024
The Effect of Repeated Capillary Refill Tests on the Cutaneous Microcirculation
Journal of Biophotonics, Vol. 17, Article e202400098
(Article in journal)
https://dx.doi.org/10.1002/jbio.202400098