gizpe86

Gizeh Perez-Tenorio

Principal Research Engineer, Docent

Docent at Division of Surgery, Orthopedics and Oncology and Project Manager at Commissioned Education Office

Presentation

I have several different assignments. I am a docent, project manager and educational developer.

Research

More than 70% of breast cancer tumors express the estrogen receptor (ER), and hormonal therapy has proven effective in reducing mortality in breast cancer. Despite this, a significant risk of late recurrence remains for patients who have undergone hormonal therapy. My research aims to investigate the molecular mechanisms underlying these late recurrences, identify high-risk patients, and propose alternative treatment strategies for recurrent disease.

More specifically, I am interested in:

  • Investigating the prevalence and significance of PIK3CA mutations in relation to disease progression and treatment response.
  • Evaluating the prognostic and therapeutic significance of tumor-infiltrating lymphocytes (TILs) by visualizing and quantifying specific subpopulations of TILs in tumor tissue.
  • Analyzing the interplay between ER, tamoxifen treatment, and the mechanisms behind what is called "tumor dormancy" in ER+ breast cancer.

Project Manager at Commissioned Education Office

Project manager for commissioned education at Linköping University, where I create collaboration between teachers from the Faculty of Medicine and various healthcare regions, companies, and other organizations. I help develop projects to educate and upskill professionals, with a focus on lifelong learning.

Teaching and Educational Development

I supervise medical students with their projects, facilitate online groups in the international course ONL, and work as an educational developer at Didacticum. Since 2023, I have been on the board of the Swedish network for educational development in higher education (Swednet).

Publications

2024

Annelie Johansson, Huma Dar, Anna Nordenskjoeld, Gizeh Perez-Tenorio, Nicholas P. Tobin, Christina Yau, Christopher C. Benz, Laura J. Esserman, Laura J. van 't Veer, Bo Nordenskjöld, Olle Stål, Tommy Fornander, Linda S. Lindstroem (2024) Differential long-term tamoxifen therapy benefit by menopausal status in breast cancer patients: secondary analysis of a controlled randomized clinical trial Journal of the National Cancer Institute (Article in journal) Continue to DOI
Josefine Sandström, Jens Bomanson, Gizeh Perez-Tenorio, Carolin Jönsson, Bo Nordenskjöld, Tommy Fornander, Linda S. Lindstrom, Olle Stål (2024) GATA3 and markers of epithelial-mesenchymal transition predict long-term benefit from tamoxifen in ER-positive breast cancer npj Breast Cancer, Vol. 10, Article 78 (Article in journal) Continue to DOI

2022

Annelie Johansson, Huma Dar, Laura J. van t Veer, Nicholas P. Tobin, Gizeh Perez-Tenorio, Anna Nordenskjöld, Ulla Johansson, Johan Hartman, Lambert Skoog, Christina Yau, Christopher C. Benz, Laura J. Esserman, Olle Stål, Bo Nordenskjöld, Tommy Fornander, Linda S. Lindstrom (2022) Twenty-Year Benefit From Adjuvant Goserelin and Tamoxifen in Premenopausal Patients With Breast Cancer in a Controlled Randomized Clinical Trial Journal of Clinical Oncology, Vol. 40, p. 4071-4082 (Article in journal) Continue to DOI
Jenny Pousette, Annelie Johansson, Carolin Jönsson, Tommy Fornander, Linda S. Lindström, Hans Olsson, Gizeh Perez-Tenorio (2022) Prognostic and Predictive Significance of Stromal Tumor-Infiltrating Lymphocytes (sTILs) in ER-Positive/HER2-Negative Postmenopausal Breast Cancer Patients Cancers, Vol. 14, Article 4844 (Article in journal) Continue to DOI
Annelie Johansson, Nancy Y. Yu, Adina Iftimi, Nicholas P. Tobin, Laura Van 'T Veer, Bo Nordenskjöld, Christopher C. Benz, Tommy Fornander, Gizeh Pérez-Tenorio, Olle Stål, Laura J. Esserman, Christina Yau, Linda S. Lindström (2022) Clinical and molecular characteristics of estrogen receptor-positive ultralow risk breast cancer tumors identified by the 70-gene signature International Journal of Cancer, Vol. 150, p. 2072-2082 (Article in journal) Continue to DOI

Organisation