Presentation

The growing antibiotic resistance problem is something my research group and its network are trying to prevent by identifying risk factors to suffer from a serious infection caused by antibiotic-resistant bacteria.

Antibiotics is a drug that has saved millions of lives annually since the discovery of penicillin and is a prerequisite for modern healthcare, but antibiotic resistance threatens its effectiveness. The World Health Organization (WHO) has estimated that 10 million people will die annually in 2050 if we fail to slow down the global increase in antibiotic-resistant bacterial infections. My research group and its network are trying to identify risk factors to suffer from a serious infection caused by antibiotic-resistant bacteria. We carry out evidence-based interventions against antibiotic resistance in low and high resistance environments, which means studies in the Nordic countries, Europe and Southeast Asia. At the same time, we carry out clinical studies in the highly specialized care in Sweden to ensure optimal antibiotic exposure in life-threatening infections with the least risk of treatment failure, resistance development and toxicity.

KP means that they are infected with CRE

Publications
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Selected publications

Dien M. Tran, Mattias Larsson, Linus Olson, Ngoc T.B. Hoang, Ngai K. Le, Dung T.K. Khu, Hung D. Nguyen, Tam V. Vu, Tinh H. Trinh, Thinh Q. Le, Phuong T.T. Phan, Binh G. Nguyen, Nhung H. Pham, Bang H. Mai, Tuan V. Nguyen, Phuong T.K. Nguyen, Nhan D. Le, Tuan M. Huynh, Le T.H. Thu, Tran Chi Thanh, Björn Berglund, Lennart E. Nilsson, Elin Bornefall, Le H. Song, Håkan Hanberger (2019)

Journal of Infection , Vol.79 , s.115-122 Continue to DOI

Vu Dinh Phu, Heiman FL Wertheim, Mattias Larsson, Behzad Nadjm, Quynh-Dao Dinh, Lennart E Nilsson, Ulf Rydell, Tuyet Thi Diem Le, Son Hong Trinh, Hung Minh Pham, Cang Thanh Tran, Hanh Thi Hong Doan, Nguyen Thua Tran, Nhan Duc Le, Nhuan Van Huynh, Thao Phuong Tran, Bao Duc Tran, Son Truong Nguyen, Thao Thi Ngoc Pham, Tam Quang Dang, Chau Van Vinh Nguyen, Yen Minh Lam, Guy Thwaites, Kinh Van Nguyen, Håkan Hanberger (2016)

PLoS ONE , Vol.11 Continue to DOI

Martin Holmbom, Christian G. Giske, Mats Fredrikson, Åse Östholm Balkhed, Carina Claesson, Lennart E Nilsson, Mikael Hoffmann, Håkan Hanberger (2016)

PLoS ONE , Vol.11 Continue to DOI

Recent publications

Tran DM, Larsson M, Olson L, Hoang NTB, Le NK, Khu DTK, Nguyen HD, Vu TV, Trinh TH, Le TQ, Phan PTT, Nguyen BG, Pham NH, Mai BH, Nguyen TV, Nguyen PTK, Le ND, Huynh TM, Anh Thu LT, Thanh TC, Berglund B, Nilsson LE, Bornefall E, Song LH, Hanberger H. High prevalence of colonisation with carbapenem-resistant Enterobacteriaceae among patients admitted to Vietnamese hospitals: Risk factors and burden of disease. J Infect. 2019 May 21. pii: S0163-4453(19)30157-4. doi: 10.1016/j.jinf.2019.05.013. [Epub ahead of print] PubMed PMID: 31125639.

Andersson M, Östholm-Balkhed Å, Fredrikson M, Holmbom M, Hällgren A, Berg S, Hanberger H. Delay of appropriate antibiotic treatment is associated with high
mortality in patients with community-onset sepsis in a Swedish setting.
Eur J Clin Microbiol Infect Dis. 2019 Mar 25. doi: 10.1007/s10096-019-03529-8. [Epub ahead of print] PubMed PMID: 30911928.

Berglund B, Hoang NTB, Tärnberg M, Le NK, Welander J, Nilsson M, Khu DTK, Nilsson LE, Olson L, Le HT, Larsson M, Hanberger H. Colistin- and carbapenem-resistant Klebsiella pneumoniae carrying mcr-1 and blaOXA-48 isolated at a paediatric hospital in Vietnam. J Antimicrob Chemother. 2018 Apr 1;73(4):1100-1102. doi: 10.1093/jac/dkx491. PubMed PMID: 29253209.

 

Down below you find a fully included list of publications.

CV Summary
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  • Senior consultant in infectious diseases in critical care, professor at the University of Linköping.
  • Leader of a research group studying antibiotic resistance (ABR) and hospital acquired infections (HAI) in low/middle and high income countries.
  • Interests are in the fields of surviving, sepsis, critical care, interventions against ABR and HAI and mechanisms of ABR.
  • Currently the main supervisor for 3 physicians in their doctoral thesis and Head teacher in infectious diseases at the medical school, Linköping University with long experience of teaching design in problem-based learning.
  • Chairman of Swedish Reference Group of Antibiotics, at Swedish Society of Medicine, 2012- .
  • Member of Drug committee County Council of Östergötland 1994- .
  • Member of National Steering Committee of Strama (Swedish Strategic Programme against Antibiotic Resistance), 2005- .
  • Member of Scientific Council of Swedish Medical Product Agency, 2014- .
  • WHO consultant in Antibiotic Resistance 2017- .
  • Member of Steering Committee of PLATINEA (Swedish Platform for Antibiotic Research) and leader of studies on limitations of antibiotic availability within this program, 2018- .

 

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