Johan Richter

My focus is on identification of brain tumour tissue and its differentiation from healthy brain tissue with optical methods that can be used during surgery. I am a senior consultant at Linköping University Hospital and affiliated with IMT.

Publications

2026

Joel Wahl, Dirce Pineda Vazquez, Elisabeth Klint, Jan Hillman, Johan Richter, Peter Milos, Kerstin Ramser (2026)

Artificial neural networks combined with quotients to preprocess Raman Spectra from different setups Vibrational Spectroscopy, Vol. 142, Article 103882 (Article in journal)

https://dx.doi.org/10.1016/j.vibspec.2025.103882

Elisabeth Klint, Johan Richter, Teresa Nordin, Ida Blystad, Martin Hallbeck, Alexandra Golby, Carl-Fredrik Westin, Karin Wårdell (2026)

Mapping brain tumor microstructure: A multimodal study of diffusion MRI, intraoperative fluorescence, and neuropathology in navigated biopsies NeuroImage: Clinical, Vol. 49, Article 103921 (Article in journal)

https://dx.doi.org/10.1016/j.nicl.2025.103921

2025

Elisabeth Klint, Anders Tisell, Ida Blystad, Martin Hallbeck, Teresa Nordin, Jan Hillman, Johan Richter, Karin Wårdell (2025)

Quantitative MRI relaxometry in brain tumor needle biopsies: Multimodal comparison with tissue fluorescence, radiology, and neuropathology PLOS ONE, Vol. 20, Article e0326765 (Article in journal)

https://dx.doi.org/10.1371/journal.pone.0326765

Karin Wårdell, Elisabeth Klint, Johan Richter (2025)

Probe-Based Fluorescence Spectroscopy for In Situ Brain Tumor Measurements During Resection and Needle Biopsies Biomedicines, Vol. 13, Article 537 (Article in journal)

https://dx.doi.org/10.3390/biomedicines13030537

2024

Elisabeth Klint, Johan Richter, Peter Milos, Martin Hallbeck, Karin Wårdell (2024)

In situ optical feedback in brain tumor biopsy: A multiparametric analysis Neuro-Oncology Advances, Vol. 6, Article vdae175 (Article in journal)

https://dx.doi.org/10.1093/noajnl/vdae175

Research

Two doctors is standing in front of a screen where a disection of a brain is visible.

Neuroengineering

Neuroengineering is a cross-disciplinary research area where engineering meets neuroscience. New methods, tools and techniques are developed and translated for clinical use. The research contributes to new knowledge of the human brain.

Optical guidance in neurosurgery

Optical techniques as laser Doppler flowmetry (LDF), diffuse reflectance spectroscopy (DRS) and fluorescence systems, and their related measurement probes, are adapted and translate for use during the neurosurgery.

Intraoperative MRI in Neurosurgery

Magnetic resonance imaging (MRI) and biomedical optic systems are used for nueroguidance during brain tumor biopsies and resection. DBS implantation and for investigation of cerebral bleedings of neurointensive care patients.

Organisation

Department of Biomedical Engineering (IMT)

A national centre for research, PhD studies and graduate studies within biomedical engineering, since 1972.

A monitor displaying health data for a patient.

Division of Biomedical Engineering (MT)

A division for research, education and innovation within the field of biomedical engineering.