The Role of the Lysosome
Lysosomes are central hub of many cellular processes such as degradation, nutrient sensing, cell death, antigen presentation and repair of ruptured plasma membrane.
The function of the lysosome is altered during several diseases including cancer and neurodegenerative disorders. This makes lysosomes attractive targets for treatment strategies and the design of novel therapeutic compounds.
Ida Eriksson, Sangeeta Nath, Per Bornefall, Ana Maria Villamil Giraldo, Karin Öllinger (2017)
Impact of high cholesterol in a Parkinsons disease model: Prevention of lysosomal leakage versus stimulation of alpha-synuclein aggregation
Kyriakos Orfanidis, Petra Wäster, Katarzyna Lundmark, Inger Rosdahl, Karin Öllinger (2017)
Evaluation of tubulin β-3 as a novel senescence-associated gene in melanocytic malignant transformation.
Petra Wäster, Ida Eriksson, Linda Vainikka, Inger Rosdahl, Karin Öllinger (2016)