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Nina Ottosson

Senior Research Coordinator

Publications

2026

Caitlyn Norman, Sara Liin, Amaia Jauregi Miguel, Nina Ottosson, Henrik Green (2026) In vitro γ-aminobutyric acid A (GABAA) receptor activity and binding interactions at the α+/γ2- interface of 53 prescription and designer benzodiazepines Communications Chemistry, Vol. 9, Article 155 (Article in journal) https://dx.doi.org/10.1038/s42004-026-02001-x

2025

Mika Jönsson, Emmanuel Bäckryd, Stefan Ljunggren, Nina Ottosson, Amaia Jauregi Miguel, Sara Liin, Antonio Checa, Craig E. Wheelock, Bijar Ghafouri (2025) System-wide targeted analysis of oxylipins and lipoproteins in chronic peripheral neuropathic pain-an explorative study Pain Reports, Vol. 10, Article e1305 (Article in journal) https://dx.doi.org/10.1097/PR9.0000000000001305
Irene Hiniesto Iñigo, Akshay Sridhar, Julien Louradour, Alicia de La Cruz Fernandez, Siri Amalia Lundholm, Amaia Jauregi Miguel, Federica Giannetti, Luca Sala, Katja E. Odening, Peter Larsson, Nina Ottosson, Sara Liin (2025) Rescue of loss-of-function long QT syndrome-associated mutations in K<sub>V</sub>7.1/KCNE1 by the endocannabinoid N-arachidonoyl-L-serine (ARA-S) British Journal of Pharmacology, Vol. 182, p. 2861-2877 (Article in journal) https://dx.doi.org/10.1111/bph.70008

2024

Andrea Benediktsdottir, Sanjeewani Sooriyaarachchi, Sha Cao, Nina Ottosson, Stefan Lindstrom, Bo Lundgren, Katharina Kloditz, Daina Lola, Olga Bobileva, Einars Loza, Diarmaid Hughes, T. Alwyn Jones, Sherry L. Mowbray, Edouard Zamaratski, Anja Sandstrom, Anders Karlen (2024) Design, synthesis, and in vitro biological evaluation of meta-sulfonamidobenzamide-based antibacterial LpxH inhibitors European Journal of Medicinal Chemistry, Vol. 278, Article 116790 (Article in journal) https://dx.doi.org/10.1016/j.ejmech.2024.116790

2021

Nina Ottosson, Malin Silverå Ejneby, Xiongyu Wu, Argel Estrada Mondragón, Michelle Nilsson, Urban Karlsson, Melanie Schupp, Salome Rognant, Thomas Andrew Jepps, Peter Konradsson, Fredrik Elinder (2021) Synthetic resin acid derivatives selectively open the hK(V)7.2/7.3 channel and prevent epileptic seizures Epilepsia, Vol. 62, p. 1744-1758 (Article in journal) https://dx.doi.org/10.1111/epi.16932

News

Male and female researchers sitting in lab + machine Qpatch 48..

New machine speeds up trials on cells

LiU researchers have used high-throughput electrophysiology experiments with a borrowed machine to see how ion channels in cells are influenced by drugs. A new collaboration with the biotech industry.
Nina Ottosson in the lab.

A drug from resin to combat epileptic seizures

New molecules, developed by researchers at Linköping University, have promising properties as possible drugs against epilepsy. A study published in the journal Epilepsia shows that several of the molecules have antiseizure effects.
Nina Ottosson and Fredrik Elinder

Drug development – not only in industry

Neuroscientists obtain support from SciLifeLab when working to develop new drugs against epilepsy. The project is the first from Linköping University that has been accepted as a full program for the Drug Discovery and Development Platform (DDD).

Publications

2026

Caitlyn Norman, Sara Liin, Amaia Jauregi Miguel, Nina Ottosson, Henrik Green (2026) In vitro γ-aminobutyric acid A (GABAA) receptor activity and binding interactions at the α+/γ2- interface of 53 prescription and designer benzodiazepines Communications Chemistry, Vol. 9, Article 155 (Article in journal) https://dx.doi.org/10.1038/s42004-026-02001-x

2025

Mika Jönsson, Emmanuel Bäckryd, Stefan Ljunggren, Nina Ottosson, Amaia Jauregi Miguel, Sara Liin, Antonio Checa, Craig E. Wheelock, Bijar Ghafouri (2025) System-wide targeted analysis of oxylipins and lipoproteins in chronic peripheral neuropathic pain-an explorative study Pain Reports, Vol. 10, Article e1305 (Article in journal) https://dx.doi.org/10.1097/PR9.0000000000001305
Irene Hiniesto Iñigo, Akshay Sridhar, Julien Louradour, Alicia de La Cruz Fernandez, Siri Amalia Lundholm, Amaia Jauregi Miguel, Federica Giannetti, Luca Sala, Katja E. Odening, Peter Larsson, Nina Ottosson, Sara Liin (2025) Rescue of loss-of-function long QT syndrome-associated mutations in K<sub>V</sub>7.1/KCNE1 by the endocannabinoid N-arachidonoyl-L-serine (ARA-S) British Journal of Pharmacology, Vol. 182, p. 2861-2877 (Article in journal) https://dx.doi.org/10.1111/bph.70008

2024

Andrea Benediktsdottir, Sanjeewani Sooriyaarachchi, Sha Cao, Nina Ottosson, Stefan Lindstrom, Bo Lundgren, Katharina Kloditz, Daina Lola, Olga Bobileva, Einars Loza, Diarmaid Hughes, T. Alwyn Jones, Sherry L. Mowbray, Edouard Zamaratski, Anja Sandstrom, Anders Karlen (2024) Design, synthesis, and in vitro biological evaluation of meta-sulfonamidobenzamide-based antibacterial LpxH inhibitors European Journal of Medicinal Chemistry, Vol. 278, Article 116790 (Article in journal) https://dx.doi.org/10.1016/j.ejmech.2024.116790

2021

Nina Ottosson, Malin Silverå Ejneby, Xiongyu Wu, Argel Estrada Mondragón, Michelle Nilsson, Urban Karlsson, Melanie Schupp, Salome Rognant, Thomas Andrew Jepps, Peter Konradsson, Fredrik Elinder (2021) Synthetic resin acid derivatives selectively open the hK(V)7.2/7.3 channel and prevent epileptic seizures Epilepsia, Vol. 62, p. 1744-1758 (Article in journal) https://dx.doi.org/10.1111/epi.16932

My research

Molecular physiology of voltage-gated ion channels.

Molecular physiology of voltage-gated ion channels

Voltage-gated ion channels are key players in all biological systems where they generate and modulate for instance the nervous impulse and pacemaker activity in the heart and the brain.

Network

Campus US with cherry blossom in the foreground.

SciLifeLab Linköping

SciLifeLab Linköping is both a local and a national research infrastructure, with unique technologies and expert competence accessible for academic and industrial researcher in the field of life sciences, health and data-driven life science.