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Peter Gennemark

Adjunct Associate Professor, Docent

My research aims to improve understanding of diabetes and cardiovascular disease and their treatment, by mathematical modelling.

Systems pharmacology – a pharma industry collaboration

Peter Gennemark (Principal scientist at AstraZeneca, Gothenburg, Sweden) is adjunct senior lecturer at IMT. Peter has an established collaboration in systems pharmacology with Gunnar Cedersund (IMT). His research is directed towards systems pharmacology in the diabetes and cardiovascular disease areas, with the aim of increasing knowledge of biology, disease progression and drug intervention in these areas.

Publications

2024

Hamidreza Arjmandi, Kajsa P. Kanebratt, Liisa Vilen, Peter Gennemark, Adam Noel (2024) 3D cell aggregates amplify diffusion signals PLOS ONE, Vol. 19, Article e0310109 (Article in journal) Continue to DOI
Sophie Rigal, Belén Casas, Kajsa P. Kanebratt, Charlotte Wennberg Huldt, Lisa U. Magnusson, Erik Mullers, Fredrik Karlsson, Maryam Clausen, Sara F. Hansson, Louise Leonard, Jonathan Cairns, Rasmus Jansson Lofmark, Carina Ammala, Uwe Marx, Peter Gennemark, Gunnar Cedersund, Tommy B. Andersson, Liisa K. Vilen (2024) Normoglycemia and physiological cortisone level maintain glucose homeostasis in a pancreas-liver microphysiological system Communications Biology, Vol. 7, Article 877 (Article in journal) Continue to DOI
Christian Simonsson, Elin Nyman, Peter Gennemark, Peter Gustafsson, Ingrid Hotz, Mattias Ekstedt, Peter Lundberg, Gunnar Cedersund (2024) A unified framework for prediction of liver steatosis dynamics in response to different diet and drug interventions Clinical Nutrition, Vol. 43, p. 1532-1543 (Article in journal) Continue to DOI
Mitra Rezaei, Hamidreza Arjmandi, Mohammad Zoofaghari, Kajsa Kanebratt, Liisa Vilen, David Janzen, Peter Gennemark, Adam Noel (2024) Spheroidal Molecular Communication via Diffusion: Signaling Between Homogeneous Cell Aggregates IEEE TRANSACTIONS ON MOLECULAR BIOLOGICAL AND MULTI-SCALE COMMUNICATIONS, Vol. 10, p. 197-210 (Article in journal) Continue to DOI

2023

Hamidreza Arjmandi, Mohamad Zoofaghari, Mitra Rezaei, Kajsa Kanebratt, Liisa Vilen, David Janzen, Peter Gennemark, Adam Noel (2023) Diffusive Molecular Communication with a Spheroidal Receiver for Organ-on-Chip Systems ICC 2023 - IEEE INTERNATIONAL CONFERENCE ON COMMUNICATIONS, p. 4464-4469 (Conference paper) Continue to DOI

Research

Illustration of a person holding arms out, and a mirrored version showing internal organs.

Systems Biology

By combining mathematical models, prior knowledge, and experimental data, we unravel biological mechanisms and contribute to the development of new drugs and clinical tools.

Research projects

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Knowledge Driven Drug Development

In this project, financed by VR medicine’s investment in pharmacy, the researchers are working with AstraZeneca to develop a new type of knowledge driven drug development.

Organisation

Institutionen för medicinsk teknik

Department of Biomedical Engineering (IMT)

A national centre for research, PhD studies and graduate studies within biomedical engineering, since 1972.
Avdelningen för medicinsk teknik

Division of Biomedical Engineering (MT)

A national centre for research, education and innovation within the field of biomedical engineering.

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