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Peter Gennemark

Adjunct Associate Professor, Docent

My research aims to improve understanding of diabetes and cardiovascular disease and their treatment, by mathematical modelling.

Systems pharmacology – a pharma industry collaboration

Peter Gennemark (Principal scientist at AstraZeneca, Gothenburg, Sweden) is adjunct senior lecturer at IMT. Peter has an established collaboration in systems pharmacology with Gunnar Cedersund (IMT). His research is directed towards systems pharmacology in the diabetes and cardiovascular disease areas, with the aim of increasing knowledge of biology, disease progression and drug intervention in these areas.

Publications

2025

Quentin Vicentini, Dennis Hekman, Deepak Bhatt, Rouven Stulz, Mahya Dezfouli, Peter Gennemark, Nicola Guzzi, Naoko Toki, Bojana Lazovic, Carolina Tangemo, Shalini Andersson, Samir EL Andaloussi, Anders Dahlen (2025) Multimeric Conjugates Using Engineered Peptide Scaffolds for Efficient siRNA Delivery Bioconjugate chemistry (Article in journal) Continue to DOI

2024

Erica Bäckström, Alessandro Bonetti, Per Johnsson, Stefan Öhlin, Anders Dahlén, Patrik Andersson, Shalini Andersson, Peter Gennemark (2024) Tissue pharmacokinetics of antisense oligonucleotides Molecular Therapy - Nucleic Acids, Vol. 35, p. 102133-102133, Article 102133 (Article in journal) Continue to DOI
Hamidreza Arjmandi, Kajsa P. Kanebratt, Liisa Vilen, Peter Gennemark, Adam Noel (2024) 3D cell aggregates amplify diffusion signals PLOS ONE, Vol. 19, Article e0310109 (Article in journal) Continue to DOI
Sophie Rigal, Belén Casas, Kajsa P. Kanebratt, Charlotte Wennberg Huldt, Lisa U. Magnusson, Erik Mullers, Fredrik Karlsson, Maryam Clausen, Sara F. Hansson, Louise Leonard, Jonathan Cairns, Rasmus Jansson Lofmark, Carina Ammala, Uwe Marx, Peter Gennemark, Gunnar Cedersund, Tommy B. Andersson, Liisa K. Vilen (2024) Normoglycemia and physiological cortisone level maintain glucose homeostasis in a pancreas-liver microphysiological system Communications Biology, Vol. 7, Article 877 (Article in journal) Continue to DOI
Christian Simonsson, Elin Nyman, Peter Gennemark, Peter Gustafsson, Ingrid Hotz, Mattias Ekstedt, Peter Lundberg, Gunnar Cedersund (2024) A unified framework for prediction of liver steatosis dynamics in response to different diet and drug interventions Clinical Nutrition, Vol. 43, p. 1532-1543 (Article in journal) Continue to DOI

Research

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Systems Biology

By combining mathematical models, prior knowledge, and experimental data, we unravel biological mechanisms and contribute to the development of new drugs and clinical tools.

Research projects

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Knowledge Driven Drug Development

In this project, financed by VR medicine’s investment in pharmacy, the researchers are working with AstraZeneca to develop a new type of knowledge driven drug development.

Organisation

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Department of Biomedical Engineering (IMT)

A national centre for research, PhD studies and graduate studies within biomedical engineering, since 1972.
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Division of Biomedical Engineering (MT)

A national centre for research, education and innovation within the field of biomedical engineering.

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