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Simon Söderholm

PhD student

Publications

2023

Simon Söderholm (2023) Exploring the tissue-specific nature of the Wnt cell signaling system: The complex world of cell communication and the search for the Achilles heel of cancer
Pierfrancesco Pagella, Simon Söderholm, Anna Nordin, Gianluca Zambanini, Valeria Ghezzi, Amaia Jauregi Miguel, Claudio Cantù (2023) The time-resolved genomic impact of Wnt/(3-catenin signaling CELL SYSTEMS, Vol. 14, p. 563-581.e7 Continue to DOI
Simon Söderholm, Amaia Jauregi Miguel, Pierfrancesco Pagella, Valeria Ghezzi, Gianluca Zambanini, Anna Nordin, Claudio Cantù (2023) Single-cell response to Wnt signaling activation reveals uncoupling of Wnt target gene expression Experimental Cell Research, Vol. 429, Article 113646 Continue to DOI

2022

Giulia Pizzolato, Lavanya Moparthi, Simon Söderholm, Claudio Cantù, Stefan Koch (2022) The oncogenic transcription factor FOXQ1 is a differential regulator of Wnt target genes Journal of Cell Science, Vol. 135, Article jcs260082 Continue to DOI
Riccardo Barchiesi, Kanat Chanthongdee, Michele Petrella, Li Xu, Simon Söderholm, Esi Domi, Gaëlle Augier, Andrea Coppola, Joost Wiskerke, Ilona Szczot, Ana Domi, Louise Adermark, Eric Augier, Claudio Cantù, Markus Heilig, Estelle Barbier (2022) An epigenetic mechanism for over-consolidation of fear memories Molecular Psychiatry, Vol. 27, p. 4893-4904 Continue to DOI

Research

teaser image claudio cantus research group

The Cantù Lab - Gene Regulation during Development and Disease

All cells of a developing organism possess the same genome. We try to understand how different groups of proteins ‘read’ the right portion of the genome in each cell, and how the perturbation of this process can cause human disease.

Organisation

Department of Biomedical and Clinical Sciences (BKV)

What characterizes the Department of Biomedical and Clinical Sciences (BKV) is the wide breadth of research and education. BKV is one of the largest departments at LiU with affiliation mainly to the Faculty of Medicine and Health Sciences.

News

Claudio Cantú and Simon Söderholm discuss the results.

Researchers shed new light on the inner workings of stem cells

Embryonic stem cells can give rise to every cell type in the body. A team of researchers has now identified a cellular mechanism that is important for the ability of these cells to maintain their state as stem cells.

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