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Sofia Nyström

Associate Professor, Docent

My research aims to advance our understanding of the pathophysiology of inborn errors of immunity and autoimmune disorders to support precision medicine approaches.

Presentation

As an Associate Professor of Clinical Immunology and Senior Consultant in Clinical Immunology and Transfusion Medicine, I bridge the gap between research and clinical practice. My research focuses on investigating various aspects of immune dysregulation. Clinically, I contribute to the diagnosis of patients with both inborn and acquired immunodeficiencies.

Publications

2025

Ramona Fust, Sofia Nyström, Britt Åkerlind, Åsa Nilsdotter-Augustinsson, Christina Petersson (2025) Experience of the COVID-19 Pandemic in the Care of Patients with Predominantly Antibody Deficiencies (PADs)-A Qualitative Study with Perspectives from Both Patients and Nurses Nursing Reports, Vol. 15, Article 104 (Article in journal) Continue to DOI
Hannes Lindahl, Fredrik Kahn, Åsa Nilsdotter-Augustinsson, Mats Fredrikson, Pontus Hedberg, Isabela Killander Möller, Lotta Hansson, Lisa Blixt, Sandra Eketorp Sylvan, Anders Österborg, Soo Aleman, Christina Carlander, Sofia N. Nyström, Peter Bergman (2025) Inborn errors of immunity are associated with increased COVID-19-related hospitalization and intensive care compared to the general population Journal of Allergy and Clinical Immunology, Vol. 155, p. 387-397.e6 (Article in journal) Continue to DOI
Isabela Killander Moller, Pontus Hedberg, Philippe Wagner, Hannes Lindahl, Sofia Nyström, Lisa Blixt, Sandra Eketorp Sylvan, Åsa Nilsdotter-Augustinsson, Anders Osterborg, Mats Fredrikson, Lotta Hansson, Fredrik Kahn, Par Sparen, Magnus Gisslen, Pontus Naucler, Peter Bergman, Soo Aleman, Christina Carlander (2025) Risk of COVID-19 hospitalisation by HIV-status and SARS-CoV-2 vaccination status during pre- and post-Omicron era in a national register-based cohort study in Sweden Infectious Diseases, Vol. 57, p. 178-191 (Article in journal) Continue to DOI

2024

Per Wågström, Maria Hjorth, Daniel Appelgren, Janne Bjorkander, Charlotte Dahle, Mats Nilsson, Åsa Nilsdotter-Augustinsson, Jan Ernerudh, Sofia Nyström (2024) Immunological characterization of IgG subclass deficiency reveals decreased Tregs and increased circulating costimulatory and regulatory immune checkpoints Frontiers in Immunology, Vol. 15, Article 1442749 (Article in journal) Continue to DOI
Sofia Nyström, Jonas Hultberg, Emelie Blixt, Åsa Nilsdotter-Augustinsson, Marie Larsson (2024) Plasma Levels of mir-34a-5p Correlate with Systemic Inflammation and Low Naïve CD4 T Cells in Common Variable Immunodeficiency Journal of Clinical Immunology, Vol. 44, Article 21 (Article in journal) Continue to DOI

Research

My research on inborn errors of immunity spans from immunological mechanisms to population-level studies. Additionally, I investigate precision medicine approaches in multiple sclerosis and immune responses to viral infections, working closely with other researchers at Linköping University.

Education

Medical Program

Organisation

Cells

Medical Inflammation and Infection Center, MIIC

Medical Inflammation and Infection Center, MIIC, research focus is on infections and inflammatory conditions, which are major concerns for human health.

News

Female researcher studies a cell plate in a laboratory.

Long-term effects on the immune system following COVID-19

The more severe the COVID-19 infection, the slower the recovery of immune cells which are necessary for the activation of the immune system. Six months after severe COVID-19, a negative impact on several types of immune cells can still be seen.
Refugee in a study situation

Popular education important for asylum seekers’ social inclusion

Committed teachers in the popular adult education sector are quietly making a huge contribution with helping asylum seekers into Swedish society. And it’s not just educational, it's also social and humanitarian. All according to two fresh LiU studies.

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