Photo of Svenja Löffert

Svenja Löffert

PhD student

Double Trouble? Unlocking the Secrets of the Second X-Chromosome in T Cells

I joined Colm Nestor’s group at BKV as a PhD student after starting my Master’s in the MSc Experimental and Medical Biosciences programme at Linköping University in 2022. Alongside my research, I am passionate about teaching: I supervise a genetics lab for medical students and lead lectures and lab sessions in the histology component of the Medical Physiology course in the BSc Experimental and Industrial Biomedicine programme.

My fascination with science began in Germany, where as a child I often visited my mother at work and watched her run lab experiments. These early experiences sparked my curiosity about the immune system and the complexity of biology. While living in the United States, I took advanced science courses and gained hands-on experience with animal models, which strengthened my passion for research and medicine.

I earned my Bachelor’s in Applied Biology at the University of Bonn, focusing on medical science and pharmacology. For my thesis, I studied T cells in acute Graft-versus-Host Disease in a Würzburg lab, connecting my growing interest in immunology and oncology.

In the Nestor group, I focus on T-cell biology with an emphasis on genetic and epigenetic regulation, studying X-chromosome inactivation during T-cell differentiation. My research explores how the second X chromosome influences CD4+ T-cell immunity and contributes to sex-based differences in immune responses.

Outside the lab, I enjoy traveling, learning new languages, and discovering different cultures. I also like to relax with a book and coffee — or practice guitar in my free time.

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