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Therése Klingstedt

Principal Research Engineer

Publications

2025

Therése Klingstedt, Hamid Shirani, Farjana Parvin, Sofie Nyström, Per Hammarström, Caroline Graff, Martin Ingelsson, Ruben Vidal, Bernardino Ghetti, Dag Sehlin, Stina Syvanen, Peter Nilsson (2025) Dual-ligand fluorescence microscopy enables chronological and spatial histological assignment of distinct amyloid-b deposits Journal of Biological Chemistry, Vol. 301, Article 108032 (Article in journal) Continue to DOI

2024

Priyanka Swaminathan, Therése Klingstedt, Vasileios Theologidis, Hjalte Gram, Johan Larsson, Lars Hagen, Nina B. Liabakk, Odrun A. Gederaas, Per Hammarström, Peter Nilsson, Nathalie van den Berge, Mikael Lindgren (2024) In Vitro Cell Model Investigation of Alpha-Synuclein Aggregate Morphology Using Spectroscopic Imaging International Journal of Molecular Sciences, Vol. 25, Article 12458 (Article in journal) Continue to DOI
Xiongyu Wu, Hamid Shirani, Ruben Vidal, Bernardino Ghetti, Martin Ingelsson, Therése Klingstedt, Peter Nilsson (2024) Distinct Chemical Determinants are Essential for Achieving Ligands for Superior Optical Detection of Specific Amyloid-ß Deposits in Alzheimer's Disease ChemistryOpen (Article in journal) Continue to DOI
Tobias Rautio, Robin Obrist, Lucas Krebs, Therése Klingstedt, Johan Dahlén, Xiongyu Wu, Henrik Green (2024) In vitro metabolism study of ADB-P-5Br-INACA and ADB-4en-P-5Br-INACA using human hepatocytes, liver microsomes, and in-house synthesized references Drug Testing and Analysis (Article in journal) Continue to DOI
Therése Klingstedt, Linda Lantz, Hamid Shirani, Junyue Ge, Jorg Hanrieder, Ruben Vidal, Bernardino Ghetti, Peter Nilsson (2024) Thiophene-Based Ligands for Specific Assignment of Distinct Aß Pathologies in Alzheimer's Disease ACS Chemical Neuroscience (Article in journal) Continue to DOI

News

Peter Nilsson.

Peter Nilsson’s molecules shine a light on Alzheimer’s research

“Even though I’m a professor now, I still spend a lot of time in the lab, as I know that when I’m working hands on, that’s when I get the new ideas,” says Peter Nilsson. He develops tracer molecules that are used in research into Alzheimer’s disease.
Microscopy image of protein aggregates stained green and red with the tracer molecules.

Tracer molecules can distinguish between very similar brain diseases

Two diseases that affect the brain, Parkinson’s disease and multiple system atrophy, show the same characteristics. Scientists have now shown that tracer molecules developed at LiU can distinguish between these diseases.

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