Therése Klingstedt

Principal Research Engineer

Publications

2025

Seyedehmahsa Mousavi, Therése Klingstedt, David Carrasco-Busturia, Ruben Vidal, Bernardino Ghetti, Mathieu Linares, Patrick Norman, Peter Nilsson (2025)

Specific chemical determinants are central for achieving ligands for selective detection of amyloid-ß deposits in Alzheimer's disease Australian journal of chemistry (Print), Vol. 78, Article CH25095 (Article in journal)

https://dx.doi.org/10.1071/CH25095

Priyanka Swaminathan, Karsten Saettem Godo, Eline Baeroe Bjorn, Therése Klingstedt, Debdeep Chatterjee, Per Hammarström, Rajeevkumar Raveendran Nair, Mikael Lindgren (2025)

Spectral Profiling of Early asyn Aggregation in HEK293 Cells Modified to Stably Express Human WT and A53T-asyn Cells, Vol. 14, Article 1542 (Article in journal)

https://dx.doi.org/10.3390/cells14191542

Greta Elovsson, Therése Klingstedt, Peter Nilsson, Ann-Christin Brorsson (2025)

Diversity of Aß aggregates produced in a gut-based Drosophila model of Alzheimer's disease PLOS ONE, Vol. 20, Article e0314832 (Article in journal)

https://dx.doi.org/10.1371/journal.pone.0314832

Therése Klingstedt, Hamid Shirani, Farjana Parvin, Sofie Nyström, Per Hammarström, Caroline Graff, Martin Ingelsson, Ruben Vidal, Bernardino Ghetti, Dag Sehlin, Stina Syvanen, Peter Nilsson (2025)

Dual-ligand fluorescence microscopy enables chronological and spatial histological assignment of distinct amyloid-b deposits Journal of Biological Chemistry, Vol. 301, Article 108032 (Article in journal)

https://dx.doi.org/10.1016/j.jbc.2024.108032

Tobias Rautio, Robin Obrist, Lucas Krebs, Therése Klingstedt, Johan Dahlén, Xiongyu Wu, Henrik Green (2025)

In vitro metabolism study of ADB-P-5Br-INACA and ADB-4en-P-5Br-INACA using human hepatocytes, liver microsomes, and in-house synthesized references Drug Testing and Analysis, Vol. 17, p. 701-712 (Article in journal)

https://dx.doi.org/10.1002/dta.3773

News

Peter Nilsson’s molecules shine a light on Alzheimer’s research

“Even though I’m a professor now, I still spend a lot of time in the lab, as I know that when I’m working hands on, that’s when I get the new ideas,” says Peter Nilsson. He develops tracer molecules that are used in research into Alzheimer’s disease.

Microscopy image of protein aggregates stained green and red with the tracer molecules.

Tracer molecules can distinguish between very similar brain diseases

Two diseases that affect the brain, Parkinson’s disease and multiple system atrophy, show the same characteristics. Scientists have now shown that tracer molecules developed at LiU can distinguish between these diseases.