Publications

Publications

PaLaCE lab members in bold
⚖️ = equal contributions
✉️ = co-corresponding authors

Peer-reviewed, original research articles

Peer-reviewed, original research articles

11. Angelini M, Savalli N, Steccanella F, Maxfield S, Pozzi S, DiFranco M, Cannon SC, Pantazis A, Olcese R. (2025) The molecular transition that confers voltage dependence to muscle contraction. Nat Commun 16:4847. DOI: 10.1038/s41467-025-59649-7

10. Wang K, Nilsson M, Angelini M, Olcese R, Elinder F, Pantazis A. (2025) A rich conformational palette underlies human CaV2.1-channel availability. Nat Commun 16:3815. DOI: 10.1038/s41467-025-58884-2
📰 LiU press release

9. Dahlberg P⚖️, Pozzi S⚖️, Bulmer L, Golluscio A, Nilsson M, Nygren A, Larsson HP, Pantazis A✉️, Gummesson A✉️. (2025) Clinical and electrophysiological characterization of a SCN5A gain-of-function mutation associated with CPVT-like arrhythmia. J Mol Cell Cardiol 203:47-58. DOI: 10.1016/j.yjmcc.2025.04.001

8. Nilsson M, Wang K, Minguez-Viñas T, Angelini M, Berglund S, Olcese R, Pantazis A. (2024) Voltage-dependent G-protein regulation of CaV2.2 (N-type) channels. Sci Adv 10(37):eadp6665. DOI: 10.1126/sciadv.adp6665
📰 LiU press release

7. Minguez-Viñas T⚖️, Prakash V⚖️, Wang K, Lindström SH, Pozzi S, Scott SA, Spiteri E, Stevenson DA, Ashley EA, Gunnarsson C, Pantazis A. (2023) Two epilepsy-associated variants in KCNA2 (KV1.2) at position H310 oppositely affect channel functional expression. J Physiol 601(23):5367-5389. DOI: 10.1113/JP285052
🏆 J Physiol Early Investigator Prize 2023 (Neuroscience) to T. Minguez-Viñas

6. Nilsson M, Lindström SH, Kaneko M, Wang K, Minguez-Viñas T, Angelini M, Steccanella F, Holder D, Ottolia M, Olcese R, Pantazis A. (2022) An epilepsy-associated KV1.2 charge-transfer-center mutation impairs KV1.2 and KV1.4 trafficking. Proc Natl Acad Sci U S A (direct submission) 119(17):e2113675119. DOI: 10.1073/pnas.2113675119
🏆 “Best Scientific Paper” award by DOMFIL, the graduate student section of the LiU Faculty of Medicine and Health Sciences
📰 LiU press release
📰 Forskning och Framsteg article
📰 Neurologi i Sverige invited article (by M. Nilsson)

5. Angelini M, Pezhouman A, Savalli N, Chang M, Steccanella F, Scranton K, Calmettes G, Ottolia M, Pantazis A, Karagueuzian H, Weiss JN, Olcese R. (2021) suppression of ventricular arrhythmias by targeting late L-type Ca2+ current. J Gen Physiol 153(12):e202012584. DOI: 10.1085/jgp.202012584
📰 Commentary by Gonano LA & Mattiazzi A (2021) J Gen Physiol DOI: 10.1085/jgp.202113009

4. Pantazis A✉️, Kaneko M, Angelini M, Steccanella F, Westerlund AM, Lindström SH, Nilsson M, Delemotte L, Saitta SC, Olcese R✉️. (2020) Tracking the motion of the KV1.2 voltage sensor reveals the molecular perturbations caused by a de novo mutation in a case of epilepsy. J Physiol 598(22):5245-5269. DOI: 10.1113/JP280438

3. Seki S, Yamamoto T, Quinn K, Spigelman I, Pantazis A, Olcese R, Wiedau-Pazos M, Chandler SH, Venugopal S. (2019) Circuit-specific early impairment of proprioceptive sensory neurons in the SOD1G93A mouse model for ALS. J Neurosci 39(44):8798-8815. DOI: 10.1523/JNEUROSCI.1214-19.2019

2. Venugopal S, Seki S, Terman DH, Pantazis A, Olcese R, Wiedau-Pazos M, Chandler SH. (2019) Resurgent Na+ current offers noise modulation in bursting neurons. PLoS Comput Biol 15(6):e1007154. DOI: 10.1371/journal.pcbi.1007154

1. Pantazis A✉️, Westerberg K, Althoff T, Abramson J, Olcese R✉️. (2018) Harnessing photoinduced electron transfer to optically determine protein sub-nanoscale atomic distances. Nat Commun 9:4738. DOI: 10.1038/s41467-018-07218-6
🏆 Selected to the Nature Communications Editor Highlights

Other publications

Other publications

5. [pre-print] Yusifov T, Gasymov O, Gudratova F, Savalli N, Pantazis A, Olcese R. (2025) Heme signaling through the gating ring apparatus of the human BK channel. SSRN. DOI: 10.2139/ssrn.5324310.

4. [pre-print] Nappi M, Frampton DJA, Kusay AS, Wang K, Miceli F, Liin SI, Taglialatela M✉️, Pantazis A✉️. (2025) Two-step voltage-sensor activation of the human KV7.4 channel and effect of a deafness-associated mutation. bioRxiv. 2025.02.04.636443. DOI: 10.1101/2025.02.04.636443.

3. [conference review] Pantazis A & Brackenbury WJ. (2024) Worldwide sodium channel conference, January 31st–February 2nd, 2024, Grindelwald, Switzerland. Bioelectricity 6(4):288-291. DOI: 10.1089/bioe.2024.0025

2. [doctoral thesis] Nilsson M. (2024) Voltage-sensor domains of ion channels: physiology, regulation, and role in disease. Linköping University Electronic Press, Linköping. DOI: 10.3384/9789180754521

1. [book chapter] Pantazis A & Olcese R. (2019) Cut-open oocyte voltage clamp technique. In: Roberts G, Watts A (eds) Encyclopedia of biophysics. Springer, Berlin, Heidelberg. DOI: 10.1007/978-3-642-35943-9_371-1