Photo of Alexandr Malusek

Alexandr Malusek

Associate Professor

Researcher in medical physics

I develop methods for (i) quantitative tissue classification via spectral and multi-energy CT, and (ii) improved radiation dosimetry with kap-meters.

Spectral and multi-energy computational tomography (CT) provides more information on the imaged tissues than the widely used conventional CT. This information can be utilized for the determination of tissue densities and mass fractions of elements constituting these tissues. The current technology cannot, however, produce all the required data. Approximate models have to be built to fill the gaps.

Kerma-area-product (KAP) meters are plane parallel ionization chambers used in diagnostic radiology for the assessment of the amount of radiation impinging on the patient during an x-ray examination. Modern medical x-ray units either contain a KAP meter or calculate the kerma-area-product from machine settings. To simplify x-ray beam positioning, most KAP meters are transparent to visible light. This is achieved by using a thin conductive layer containing elements with high atomic numbers. This construction detail leads to severe energy dependence of these ionization chambers, which limits measurement accuracy. Relative errors up to about 20-25% are common and complicate x-ray diagnostic protocol optimization.

Short information


2008 PhD in Medical Physics

Field of Teaching

  • TVFA02
  • TBMT02



Ann-Sofi Björkman, Alexandr Malusek, Håkan Gauffin, Anders Persson, Seppo Koskinen (2023) Spectral photon-counting CT: Image quality evaluation using a metal-containing bovine bone specimen European Journal of Radiology, Vol. 168, Article 111110 Continue to DOI
Maria Magnusson, Gudrun Alm Carlsson, Michael Sandborg, Åsa Carlsson Tedgren, Alexandr Malusek (2023) On the Choice of Base Materials for Alvarez-Macovski and DIRA Dual-energy Reconstruction Algorithms in CT Photon Counting Computed Tomography: Clinical Applications, Image Reconstruction and Material Discrimination, p. 153-175 Continue to DOI


Benjamin Klintstrom, Lilian Henriksson, Rodrigo Moreno, Alexandr Malusek, Orjan Smedby, Mischa Woisetschläger, Eva Klintström (2022) Photon-counting detector CT and energy-integrating detector CT for trabecular bone microstructure analysis of cubic specimens from human radius EUROPEAN RADIOLOGY EXPERIMENTAL, Vol. 6, Article 31 Continue to DOI