Ion channel biophysics

Understanding the basis of cellular excitability in health and disease.

Our bodies are “wet computers”, utilizing electrical signals to mediate nerve function, a regular heart rhythm, muscle contraction and other physiological functions. Voltage-gated ion channels are fascinating macromolecules that span the cell membrane and, upon receipt of an electrical signal, allow specific ions to cross into or out of the cell. By controlling ionic conduction, ion channels govern cellular excitability; that is, the ability of a cell to generate, and respond to, electrical signals. 

My group combines innovative electrophysiological, optical and computational approaches to investigate how the intricate molecular architecture of ion channels relates to their function and regulation; and how ion channel function or dysfunction governs cellular excitability in health and disease.

Selected publications
Show/Hide content

2018

2016

2014

2012

CV
Show/Hide content

Positions and Education

  • 2018 -
    Senior Lecturer, Linköping University, Dept. of Clinical & Experimental Medicine
  • 2012-2018
    Assistant Researcher, University of California at Los Angeles, Dept. of Anesthesiology 
  • 2008-2012
    Postdoc, University of California at Los Angeles, Dept. of Anesthesiology
  • 2006-2008
    Postdoc, University College London, Dept. of Pharmacology
  • 2002-2006
    PhD, Cambridge University (Churchill College)
  • 1999-2002
    BA in Natural Sciences, Cambridge University (Churchill College)

 

News
Show/Hide content

Related research
Show/Hide content

Organisation
Show/Hide content