Photo of Baris Ata Borsa

Baris Ata Borsa

Principal Research Engineer

Dr. Borsa’s research is focused on developing new targeted therapeutics and diagnostics for infectious diseases using nucleic acid probes.

Dr. Baris Ata Borsa graduated from Istanbul University Cerrahpasa Medical Faculty in 2004 and obtained Medical Microbiology Specialist degree in 2009 after 4 years of residency period at Sisli Etfal Training and Research Hospital, Istanbul.  

From 2009 to 2013, he worked in different hospitals as specialist. In 2013, his academic career started as Assistant Professor at Altinbas University School of Medicine, Department of Medical Microbiology where he worked for 4 years. In this faculty, he was also responsible for many administrative assignments such as being Vice Dean of Medical Faculty, member of University Board of Education, and Head of Medical Microbiology Department. 

During the same years, he was also working as a specialist at Özel Doga Hospital and doing PhD at Istanbul University Cerrahpasa Medical Faculty, Department of Medical Microbiology. 

In 2017, he started working at Yeditepe University Medical Faculty, Department of Medical Microbiology as Assistant Professor and Yeditepe University Hospitals as specialist. 
He obtained Associate Professor degree from Turkish Presidency of Inter-University Council in 2018. Same year, he joined Frank Hernendez's group as postdoctoral researcher at Linköping University for a new journey aiming to develop new targeted antibiotics which were becoming crucial because of globally increasing antimicrobial resistance.

His main research field is medical bacteriology, particularly antimicrobial resistance, even though he worked in all other sub-disciplines of the field (virology, mycology, parasitology, immunology, molecular microbiology) for many years. In his current project, he developed a first-in-kind targeted oligonucleotide antibiotic against a major human pathogen, Staphylococcus aureus, using its nuclease enzyme activity as biomarker.

He is also co-inventor in the patent application of this new therapeutic approach. 

CV in short

Find Boris Ata Barsa at LinkedIn.

Expertise

  • Bacteriology
  • Antimicrobial resistance
  • Antimicrobial susceptibility testing
  • Animal models of infections
  • Drug discovery and development
  • Targeting nucleases for diagnostics and therapeutics

Education

Undergraduate: Cerrahpasa Medical Faculty, Istanbul University, Istanbul/Turkey
Medical Specialty: Department of Medical Microbiology, Sisli Etfal Training and Research Hospital, Istanbul/Turkey.
PhD: Department of Medical Microbiology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul/Turkey

Previous positions

  • Resident physician (doctor)
    • Medical Microbiology Department, Sisli Etfal Training and Research Hospital, Istanbul/Turkey (2005-2009)
  • Medical microbiology specialist
    • Izmir Military Hospital, Izmir/Turkey (2009-2010)
    • Mardin Gynecology and Pediatrics Hospital, Mardin/Turkey (2010-2011)
    • Özel Doga Hospital, Istanbul/Turkey (2011-2017)
    • Yeditepe University Hospitals, Istanbul/Turkey (2017-2018)
  • Assistant Professor
    • Medical Microbiology Department, Altinbas University School of Medicine, Istanbul/Turkey (2013-2017)
    • Yeditepe University School of Medicine, Istanbul/Turkey (2017-2018)
  • Postdoctoral researcher
    • Linköping University Department of Physics, Chemistry and Biology. Nucleic Acids Technologies Laboratory, Linköping/Sweden (2018-2020)
  • Principal Research Engineer
    • Linköping University Department of Physics, Chemistry and Biology. Nucleic Acids Technologies Laboratory, Linköping/Sweden (2020-onwards)

Teaching

  • Hematopoeitic System, Immunology and Microbiology, Undergraduate / Altinbas University School of Medicine
  • Clinical Microbiology and Infectious Diseases, Undergraduate / Altinbas University School of Medicine
  • Introduction to Clinical Medicine, Undergraduate / Altinbas University School of Medicine 
  • Nosocomial Infections, Undergraduate / Altinbas University School of Medicine 
  • Autoimmune Diseases, Undergraduate / Altinbas University School of Medicine 
  • Subacute Bacterial Endocarditis, Undergraduate / Altinbas University School of Medicine 
  • Sexually Transmitted Diseases, Undergraduate / Altinbas University School of Medicine 
  • Approach to Respiratory System Infections in Adults, Undergraduate / Altinbas University School of Medicine
  • Urinary Tract Infections, Undergraduate / Altinbas University School of Medicine
  • Pharmaceutical Microbiology and Immunology, Undergraduate / Altinbas University School of Pharmacy
  • Oral Microbiology I, Periodontology Postgraduate Programme / Altinbas University School of Dentistry
  • Immunology, Orthodontics PhD Programme / Altinbas University School of Dentistry
  • Medical Microbiology, Undergraduate / Yeditepe University Faculty of Medicine, Yeditepe University Faculty of Dentistry, and Yeditepe University Faculty of Pharmacy

Publications

Find my research

Research Gate
Google Scholar
ORCID

Selected Publications

  • Borsa BA, Tuna B, Hernandez FJ, Hernandez LI, Bayramoglu G, Arica YM, Schafer T, Ozalp VC. Combined usage of aptamer-based magnetic nanoparticles and micrococcal nuclease spesific flourescent releasing nanokeepers in detection of Staphylococcus aureus directly from blood samples. Biosensors and Bioelectronics 2016; 86: 27-32.
  • Borsa BA, Aldag ME, Tunali B, Dinc U, Gungordu Dalar Z, Ozalp VC. Sepsis Caused by a Rare Opportunistic Pathogen: Bacillus pumilus. Bulletin of Microbiology 2016; 50(3): 466-70.
  • Vakifahmetoglu C, Zeydanlı D, Ozalp VC, Borsa BA, Soraru GD. Hierarchical porosity: a promising platform for multidrug delivery systems. Materials and Design 2017; 140(2018): 37-44.
  • Demirci M, Guzel AD, Sahin AA, Yorulmaz E, Ersahin SS, Borsa BA. Human papillomavirus prevalence and genotype distribution among Turkish women with or without cervical lesion. Indian Journal of Medical Microbiology 2018; 36(4): 517-21.
  • Borsa BA, Demirci M, Gungordu Dalar Z, Karabiyik G, Aygün G, Küçükbasmaci O. Molecular mechanisms of colistin resistance among Klabsiella pneumoniae strains. Clinical Laboratory 2019; 65(7): 1125-30.
  • Balian A, Garcia Gonzalez J, Bastida N, Akhtar KK, Borsa BA, Hernandez FJ. Kinetic Screening of Nuclease Activity using Nucleic Acid Probes (Knut and Alice Wallenberg Foundation Project). Journal of Visualized Experiments 2019; (153): e60005.
  • Ucak S, Sudagidan M, Borsa BA, Mansuroglu B, and Ozalp VC. Aptamer Targeted Teicoplanin Encapsulated PLGA Nanoparticles for Methicilin-resistant Staphylococcus aureus. World Journal of Microbiology and Biotechnology 2020; 36:69.
  • Borsa BA, Sudagidan M, Aldag ME, Baris II, Acar EE, Acuner C, Kavruk M, Ozalp VC. Antibiotic administration in targeted nanoparticles protects the faecal microbiota of mice. RSC Medicinal Chemistry 2021; 12, 380-3.
  • Dursun AD, Borsa BA, Bayramoglu G, Arica MY, Ozalp VC. Surface plasmon resonance aptasensor for Brucella detection in milk. Talanta 2022; 239:123074.

Publications in chronological order

2024

Lingyin Meng, Sheng Liu, Baris Ata Borsa, Mats Eriksson, Wing Cheung Mak (2024) A conducting polymer-based array with multiplex sensing and drug delivery capabilities for smart bandages COMMUNICATIONS MATERIALS, Vol. 5, Article 28 (Article in journal) Continue to DOI
Garazi Goikoetxea, Khadija-Tul Kubra Akhtar, Alona Prysiazhniuk, Baris Ata Borsa, Mehmet Ersoy Aldag, Murat Kavruk, Veli C. Ozalp, Frank Hernandez (2024) Fluorescent and electrochemical detection of nuclease activity associated with <i>Streptococcus pneumoniae</i> using specific oligonucleotide probes The Analyst (Article in journal) Continue to DOI

2023

Baris Ata Borsa, Luiza I. Hernandez, Tania Jiménez, Chaitanya Tellapragada, Christian G Giske, Frank J Hernandez (2023) Therapeutic-oligonucleotides activated by nucleases (TOUCAN): A nanocarrier system for the specific delivery of clinical nucleoside analogues. Journal of Controlled Release, Vol. 361, p. 260-269 (Article in journal) Continue to DOI

2022

Ali D. Dursun, Baris Ata Borsa, Gulay Bayramoglu, M. Yakup Arica, Veli C. Ozalp (2022) Surface plasmon resonance aptasensor for Brucella detection in milk Talanta: The International Journal of Pure and Applied Analytical Chemistry, Vol. 239, Article 123074 (Article in journal) Continue to DOI

2021

Baris Ata Borsa, Mert Sudagidan, Mehmet E. Aldag, Isik I. Baris, Elif E. Acar, Cagatay Acuner, Murat Kavruk, Veli C. Ozalp (2021) Antibiotic administration in targeted nanoparticles protects the faecal microbiota of mice RSC MEDICINAL CHEMISTRY, Vol. 12, p. 380-383 (Article in journal) Continue to DOI

Organisation

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