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Mikael Forsgren

Adjunct Associate Professor

As an Associate Professor at HMV my aim is to increase the knowledge around magnetic resonance physics and methodology in Sweden. I research MR-based body composition and its link to disease and treatment, mainly in metaboic liver disease.

Presentation

Magnetic resonance imaging based measurement of body composition in metabolic and chronic liver diseases.

Magnetic resonance imaging-based measurement of body composition in metabolic and chronic liver diseases

I have been involved in liver-related research using magnetic resonance imaging (MRI) and spectroscopy (MRS) since 2009 – both in academia and industry. I have a MSc in biotechnology and PhD in medical sciences. My education focused heavily on MR, mathematical modelling (systems biology), and clinical research. My doctoral thesis explored a range of MR methods to replace the liver needle biopsy and quantify liver function. Chronic liver diseases at different stages are a common topic in my research efforts. In addition to exploring body and muscle composition in liver diseases, I have applied my MR expertise to assess muscle composition in COPD, fibromyalgia syndrome, and physical exercise. In parallel with my role at Linköping University I am employed as a researcher at a company spun out of MRI research from Linköping University (CMIV). It was founded 12 years ago by researchers active at Linköping University. At the company, I research the same question as I do at Linköping University, primarily in several projects with key opinion leaders in the USA at a range of well-known university hospitals.

Today my main research focus is on applying the MR-methods I know to link body composition to disease states, progression, risk stratification and treatment on patients suffering from steatotic liver disease, liver fibrosis, liver cirrhosis, and those in need of a liver transplant.

I believe that MR is a very important modality for both research and clinical application. Therefore, it feels great that I have the opportunity to increase that knowledge in Sweden through the courses I lead or lecture in.

“Pretending to know everything closes the door to learn more” – Neil deGrasse Tyson (Cosmos, 2014)

Short texts

CV

Education

  • 2017 PhD in Medical Science (Magnetic Resonance Physics, Systems Biology), Linköping University
  • 2011 MSc in engineering biotechnology, Linköping University

Employment

  • 2023 – Adj. Associate Professor, Linköping University
  • 2018 – Senior Scientist, AMRA Medical AB
  • 2019–2023 Adj. Assistant Lecturer, Linköping University
  • 2017–2019 Senior Applications Engineer, Wolfram MathCore AB
  • 2013–2017 Industrial PhD student, Wolfram MathCore/Linköping University
  • 2012–2017 Applications Engineer, Wolfram MathCore AB
  • 2011–2012 Research Assistant/Engineer, Region Östergötland

Assignments (selection)

  • 2016–2017 Student representative CMIV Board, Linköping University

Teaching

  • Course coordinator, examiner: Physics and Methodology in Magnetic Resonance Tomography, MRT, 7.5 credits, 8FA253.
  • Course coordinator: Physics and Methodology in Magnetic Resonance Imaging (MRI), 5.0 credits, 8FO0110.
  • Lecturer: Clinical Hepatology, 5.0 credits, 8FO0140.
  • Lecturer: Advanced course in abdominal Magnetic Resonance Imaging (MRI), 7.5 credits, 8FA312.

Reseach

  • ACCESS-ESLD
  • DETECT-HCC
  • EPSONIP
  • NFL
  • SCORE

Publications

Cover of publication 'image from publication'
Patrik Nasr, Mikael F. Forsgren, Simone Ignatova, Nils Dahlström, Gunnar Cedersund, Olof Dahlqvist Leinhard, Bengt Norén, Mattias Ekstedt, Peter Lundberg, Stergios Kechagias (2017)

Gastroenterology , Vol.153 , s.53-+ Continue to DOI

Cover of publication ''
Mikael F Forsgren, Patrik Nasr, Markus Karlsson, Nils Dahlström, Bengt Norén, Simone Ignatova, Ralph Sinkus, Gunnar Cedersund, Olof Dahlqvist Leinhard, Mattias Ekstedt, Stergios Kechagias, Peter Lundberg (2020)

Scandinavian Journal of Gastroenterology , Vol.55 , s.848-859 Continue to DOI

Cover of publication ''
Manu V. Chakravarthy, Mohammad S. Siddiqui, Mikael Forsgren, Arun J. Sanyal (2020)

Frontiers in Endocrinology , Vol.11 Continue to DOI

2024

Mikael Forsgren, Stewart Pine, Claire Royalle Harrington, Dyanna Gregory, Mikael Petersson, Mary Rinella, Olof Dahlqvist Leinhard, Lisa B. VanWagner (2024) Body composition and muscle composition phenotypes in patients on waitlist and shortly after liver transplant - results from a pilot study BMC Gastroenterology, Vol. 24, Article 356 (Article in journal) Continue to DOI
Chandra Bhati, Danielle Kirkman, Mikael Forsgren, Hiba Kamal, Hiba Khan, Sherry Boyett, Olof Dahlqvist Leinhard, Jennifer Linge, Vaishali Patel, Samarth Patel, Susan Wolver, Mohammad S. Siddiqui (2024) Liver transplant recipients have worse metabolic body phenotype compared with matched non-transplant controls JGH OPEN, Vol. 8, Article e70024 (Article in journal) Continue to DOI
Avesh J. Thuluvath, Mikael Forsgren, Daniela P. Ladner, Amit D. Tevar, Andres Duarte-Rojo (2024) Utilizing a novel MRI technique to identify adverse muscle composition in end-stage liver disease: A pilot study ANNALS OF HEPATOLOGY, Vol. 29, Article 101508 (Article in journal) Continue to DOI
Björn Gerdle, Olof Dahlqvist Leinhard, Eva Lund, Peter Lundberg, Mikael Forsgren, Bijar Ghafouri (2024) Pain and the biochemistry of fibromyalgia: patterns of peripheral cytokines and chemokines contribute to the differentiation between fibromyalgia and controls and are associated with pain, fat infiltration and content FRONTIERS IN PAIN RESEARCH, Vol. 5, Article 1288024 (Article in journal) Continue to DOI
Anh T. Bui, Rahul Chaudhari, Chandra Bhati, Susan Wolver, Samarth Patel, Sherry Boyett, Marie Claire Evans, Hiba Kamal, Vaishali Patel, Mikael F Forsgren, Arun J. Sanyal, Danielle Kirkman, Mohammad Shadab Siddiqui (2024) Reduced metabolic flexibility is a predictor of weight gain among liver transplant recipients Liver transplantation, Vol. 30, p. 192-199 (Article in journal) Continue to DOI

Research

Coworkers

Organisation