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Mattias Ekstedt

Deputy Head of Department, Senior Associate Professor

My research aims to improve the quality of life for patients through innovative treatments and diagnostic techniques. Through my teaching, I seek to spread knowledge about chronic liver diseases and convey what makes the medical profession exciting.

About me

CV

  • 2003 Medical Degree
  • 2008 Doctoral Degree
  • 2010-2015 LiÖ Research Assistant (Fo-Ass)
  • 2011 Specialist, Internal Medicine
  • 2013 STINT-Scholarship “Excellence in Teaching”, New York University, USA
  • 2013-2019 Medical Doctor (Specialistläkare), Gastroenterology and Hepatology
  • 2015-2021 Senior Lecturer (Kombinationsanställning), HMV
  • 2019- Main/Co-Supervisor for > 15 PhD students
  • 2019- Senior Consultant (Överläkare), Stomach and Intestine Department
  • 2020 Associate Professor (Docent), Gastroenterology and Hepatology
  • 2021- Senior Associate Professor, HMV

Teaching assignments

Medical Programme, LiU

  • Academic Group Supervisor
  • Course Manager K6
  • Member and former Chair, GNM Theme Group
  • Lecturer, Seminar Leader
  • Developed MEQ exams, OSCE, and oral/practical exams
  • Main Supervisor for Advanced Projects

Nursing Programme, LiU

  • Examiner, IMO3

Networks

  • Founder and Member, The Study Group for Ectopic Fat Storage
  • Member, SWEHEP
  • Board Member, Mag-Tarmfonden
  • Steering Committee Member SweLiv
  • Former National Lead for Sweden in LITMUS
  • Member, EASL International Liver Foundation NAFLD Policy Review Study Group
  • Center for Medical Image Science and Visualization, CMIV

Awards

News

Mattias Ekstedt, Nils Dahlström, Peter Lundberg, Bengt Norén and Patrik Nasr.

Adverse muscle composition linked to risk in fatty liver disease

Obesity and a sedentary lifestyle contribute to an increasing number of people developing fatty liver disease. According to a new study, poor muscle health may be a marker of risk for developing sequelae.
Mattias Ekstedt, Nils Dahlström, Peter Lundberg, Bengt Norén and Patrik Nasr.

Liver examinations without needles

How is your liver doing? Decades of research into the use of magnet resonance imaging is now being put to work to gain information about patients’ livers – without needles.
A jogger with bad condition is getting behind the other joggers.

Poor fitness and obesity linked to later chronic disease

Obesity and poor fitness in adolescence are associated with receiving disability pension due to cardiovascular disease later in life, according to a study. The good news are that even a small improvement in fitness is associated with lower risk.

Publications

Cover of publication ''
Mattias Ekstedt, Lennart E Franzén, Ulrik L Mathiesen, Lars Thorelius, Marika Holmqvist, Göran Bodemar, Stergios Kechagias (2006)
Long-term follow-up of patients with NAFLD and elevated liver enzymes.

Hepatology , Vol.44 , s.865-873 Continue to DOI

Cover of publication ''
Mattias Ekstedt, Hannes Hagström, Patrik Nasr, Mats Fredrikson, Per Stål, Stergios Kechagias, Rolf Hultcrantz (2015)
Fibrosis stage is the strongest predictor for disease-specific mortality in NAFLD after up to 33 years of follow-up

Hepatology , Vol.61 , s.1547-1554 Continue to DOI

Cover of publication ''
Patrik Nasr, Simone Ignatova, Stergios Kechagias, Mattias Ekstedt (2018)
Natural history of nonalcoholic fatty liver disease: A prospective follow-up study with serial biopsies.

Hepatology communications , Vol.2 , s.199-210 Continue to DOI

2025

Nanicha Siriwong, Supachaya Sriphoosanaphan, Pakanat Decharatanachart, Tanat Yongpisarn, Stephen Kerr, Sombat Treeprasertsuk, Thodsawit Tiyarattanachai, Terapap Apiparakoon, Hannes Hagstroem, Camilla Akbari, Mattias Ekstedt, Terry Yip, Grace Wong, Takanori Ito, Masatoshi Ishigami, Hidenori Toyoda, Noam Peleg, Amir Shlomai, Yuya Seko, Yoshio Sumida, Miwa Kawanaka, Keisuke Hino, Roongruedee Chaiteerakij (2025) Role of noninvasive tests on the prediction of hepatocellular carcinoma in nonalcoholic fatty liver disease patients without cirrhosis: a systematic review and meta-analysis of aggregate and individual patient data European Journal of Gastroenterology and Hepathology, Vol. 37, p. 358-369 (Article in journal) Continue to DOI
Yasaman Vali, Anne-Marieke van Dijk, Jenny Lee, Jerome Boursier, Vlad Ratziu, Carla Yunis, Joern M. Schattenberg, Luca Valenti, Manuel Romero Gomez, Detlef Schuppan, Salvatore Petta, Mike Allison, Mark L. Hartman, Kimmo Porthan, Jean-Francois Dufour, Elisabetta Bugianesi, Amalia Gastadelli, Zoltan Derdak, Celine Fournier-Poizat, Elizabeth Shumbayawonda, Michael Kalutkiewicz, Hannele Yki-Jarvinen, Mattias Ekstedt, Andreas Geier, Aldo Trylesinski, Sven Francque, Clifford Brass, Michael Pavlides, Adriaan G. Holleboom, Max Nieuwdorp, Quentin M. Anstee, Patrick M. Bossuyt (2025) Precision in Liver Diagnosis: Varied Accuracy Across Subgroups and the Need for Variable Thresholds in Diagnosis of MASLD Liver international, Vol. 45, Article e16240 (Article in journal) Continue to DOI

2024

Annika Bergquist, Mattias Ekstedt, Hannes Hagstrom, Gunnar Jarnerot, Stefan Lindgren, Emma Nilsson, Nils Nyhlin, Fredrik Rorsman, Per Stal, Marten Werner, Swehep, Stergios Kechagias (2024) Forty years of successful national research collaboration in liver disease - the Swedish experience Scandinavian Journal of Gastroenterology, Vol. 59, p. 1314-1321 (Article, review/survey) Continue to DOI
Michele Vacca, Ioannis Kamzolas, Lea Morch Harder, Fiona Oakley, Christian Trautwein, Maximilian Hatting, Trenton Ross, Barbara Bernardo, Anouk Oldenburger, Sara Toftegaard Hjuler, Iwona Ksiazek, Daniel Linden, Detlef Schuppan, Sergio Rodriguez-Cuenca, Maria Manuela Tonini, Tamara R. Castaneda, Aimo Kannt, Cecilia M. P. Rodrigues, Simon Cockell, Olivier Govaere, Ann K. Daly, Michael Allison, Kristian Honnens de Lichtenberg, Yong Ook Kim, Anna Lindblom, Stephanie Oldham, Anne-Christine Andreasson, Franklin Schlerman, Jonathon Marioneaux, Arun Sanyal, Marta B. Afonso, Ramy Younes, Yuichiro Amano, Scott L. Friedman, Shuang Wang, Dipankar Bhattacharya, Eric Simon, Valerie Paradis, Alastair Burt, Ioanna Maria Grypari, Susan Davies, Ann Driessen, Hiroaki Yashiro, Susanne Pors, Maja Worm Andersen, Michael Feigh, Carla Yunis, Pierre Bedossa, Michelle Stewart, Heather L. Cater, Sara Wells, Joern M. Schattenberg, Quentin M. Anstee, Dina Tiniakos, James W. Perfield, Evangelia Petsalaki, Peter Davidsen, Antonio Vidal-Puig, Quentin M. Anstee, Ann K. Daly, Simon Cockell, Dina Tiniakos, Pierre Bedossa, Alastair Burt, Fiona Oakley, Heather J. Cordell, Christopher P. Day, Kristy Wonders, Paolo Missier, Matthew McTeer, Luke Vale, Yemi Oluboyede, Matt Breckons, Jo Boyle, Patrick M. Bossuyt, Hadi Zafarmand, Yasaman Vali, Jenny Lee, Max Nieuwdorp, Adriaan G. Holleboom, Athanasios Angelakis, Joanne Verheij, Vlad Ratziu, Karine Clement, Rafael Patino-Navarrete, Raluca Pais, Valerie Paradis, Detlef Schuppan, Joern M. Schattenberg, Rambabu Surabattula, Sudha Myneni, Yong Ook Kim, Beate K. Straub, Antonio Vidal-Puig, Michele Vacca, Sergio Rodrigues-Cuenca, Mike Allison, Ioannis Kamzolas, Evangelia Petsalaki, Mark Campbell, Chris J. Lelliott, Susan Davies, Matej Oresic, Tuulia Hyotylainen, Aidan McGlinchey, Jose M. Mato, Oscar Millet, Jean-Francois Dufour, Annalisa Berzigotti, Mojgan Masoodi, Naomi F. Lange, Michael Pavlides, Stephen Harrison, Stefan Neubauer, Jeremy Cobbold, Ferenc Mozes, Salma Akhtar, Seliat Olodo-Atitebi, Rajarshi Banerjee, Elizabeth Shumbayawonda, Andrea Dennis, Anneli Andersson, Ioan Wigley, Manuel Romero-Gomez, Emilio Gomez-Gonzalez, Javier Ampuero, Javier Castell, Rocio Gallego-Duran, Isabel Fernandez-Lizaranzu, Rocio Montero-Vallejo, Morten Karsdal, Daniel Guldager Kring Rasmussen, Diana Julie Leeming, Antonia Sinisi, Kishwar Musa, Estelle Sandt, Maria Manuela Tonini, Elisabetta Bugianesi, Chiara Rosso, Angelo Armandi, Fabio Marra, Amalia Gastaldelli, Gianluca Svegliati, Jerome Boursier, Sven Francque, Luisa Vonghia, An Verrijken, Eveline Dirinck, Ann Driessen, Mattias Ekstedt, Stergios Kechagias, Hannele Yki-Jarvinen, Kimmo Porthan, Johanna Arola, Saskia van Mil, George Papatheodoridis, Helena Cortez-Pinto, Ana Paula Silva, Cecilia M. P. Rodrigues, Luca Valenti, Serena Pelusi, Salvatore Petta, Grazia Pennisi, Luca Miele, Antonio Liguori, Andreas Geier, Monika Rau, Christian Trautwein, Johanna Reissing, Guruprasad P. Aithal, Susan Francis, Naaventhan Palaniyappan, Christopher Bradley, Paul Hockings, Moritz Schneider, Philip N. Newsome, Stefan Hubscher, David Wenn, Jeremy Magnanensi, Aldo Trylesinski, Rebeca Mayo, Cristina Alonso, Kevin Duffin, James W. Perfield, Yu Chen, Mark L. Hartman, Carla Yunis, Melissa Miller, Yan Chen, Euan James McLeod, Trenton Ross, Barbara Bernardo, Corinna Schoelch, Judith Ertle, Ramy Younes, Harvey Coxson, Eric Simon, Joseph Gogain, Rachel Ostroff, Leigh Alexander, Hannah Biegel, Mette Skalshoi Kjaer, Lea Morch Harder, Naba Al-Sari, Sanne Skovgard Veidal, Anouk Oldenburger, Jens Ellegaard, Maria-Magdalena Balp, Lori Jennings, Miljen Martic, Jurgen Loffler, Douglas Applegate, Richard Torstenson, Daniel Linden, Celine Fournier-Poizat, Anne Llorca, Michael Kalutkiewicz, Kay Pepin, Richard Ehman, Gerald Horan, Gideon Ho, Dean Tai, Elaine Chng, Teng Xiao, Scott D. Patterson, Andrew Billin, Lynda Doward, James Twiss, Paresh Thakker, Zoltan Derdak, Hiroaki Yashiro, Henrik Landgren, Carolin Lackner, Annette Gouw, Prodromos Hytiroglou, Olivier Govaere, Clifford Brass (2024) An unbiased ranking of murine dietary models based on their proximity to human metabolic dysfunction-associated steatotic liver disease (MASLD) Nature Metabolism, Vol. 6, p. 1178-+ (Article in journal) Continue to DOI
Ying Shang, Camilla Akbari, Maja Dodd, Xiao Zhang, Tongtong Wang, Thomas Jemielita, Gail Fernandes, Samuel S. Engel, Patrik Nasr, Johan Vessby, Fredrik Rorsman, Stergios Kechagias, Per Stal, Mattias Ekstedt, Hannes Hagstrom (2024) Association between longitudinal biomarkers and major adverse liver outcomes in patients with non-cirrhotic metabolic dysfunction-associated steatotic liver disease Hepatology (Article in journal) Continue to DOI

Research

A X-ray image of a liver

DETECT-HCC-ESLD

Photo of EPSONIP project meeting

EPSOMiP

EPSONIP explores the link between fatty liver, epicardial fat and cardiovascular disease in type 2 diabetes.
View of a scanner room bathed in blue light

ACCESS

transparent image, place holder

Metabolic dysfunction-associated steatotic liver disease (MASLD)

Metabolic dysfunction-associated steatotic liver disease (MASLD) previously known as non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease which has become the most common liver disease affecting adults and children.
Five man are standing in front of a big screen showing MR images.

The study group of ectopic fat storage

Vi studerar hur fettinlagring i olika organ, så som lever, muskel och hjärta, ökar risken för sjukdomsutveckling. Förhoppningen är att kartläggning kommer att hjälpa oss att identifiera de individer som löper högst risk att utveckla sjukdom.

Earlier projects

LITMUS - Liver Investigation: Testing Marker Utility in Steatohepatitis (2017-2022) CORDIS keyword LITMUS

Coworkers

patna19

Patrik Nasr

Adjunct Associate Professor

Stergios Kechagias

Professor

mikfo34

Mikael Forsgren

Adjunct Associate Professor

oloda24

Olof Dahlqvist Leinhard

Associate Professor

Jennifer Linge

Affilierad forskare

gunce57

Gunnar Cedersund

Associate Professor, Docent

valki67

Valentin Kindesjö
nilda87

Nils Dahlström

Associate Professor, Head of Unit

Wolf Bartholomä

PhD student

petlu11

Peter Lundberg

Adjunct Professor

johki53

Johan Kihlberg
carca13

Carl-Johan Carlhäll

Professor

tineb49

Tino Ebbers

Professor

cared19

Carl Fredholm

Joakim Alfredsson

Senior Associate Professor

torol42

Torsten Olbers

Professor

bijgh14

Bijar Ghafouri

Professor, Head of Unit

cecka94

Cecilia Jönsson

Principal Research Engineer

chrsi30

Christian Simonsson
marhe38

Martin Henriksson

Senior Associate Professor

freir97

Fredrik Iredahl

Associate Professor, Docent

Martin Ulander

Martin Bergram
karra46

Karin Rådholm

Senior Associate Professor

wilba28

Wile Balkhed
marho50

Markus Holmberg

Byron Lykiardopoulos

Jonas Agholme

Bengt Norén

Simone Ignatova

Kim Ahtola

Organisation

Illustration of the letters HMV

Department of Health, Medicine and Caring Sciences (HMV)

The research areas at HMV include experimental basic research to clinical, social and public health research. We conduct high-quality education in the sought-after care professions.
Close up of three doctors dressed in surgical clothes. One stands with his back to the camera.

Division of Diagnostics and Specialist Medicine (DISP)

The division consists of three units (internal medicine, cardiovascular and radiological sciences) and contains seven subject areas within which research and teaching are conducted.
Five people in a laboratory.

Faculty of Medicine and Health Sciences (MEDFAK)

The Faculty of Medicine and Health Sciences conducts research and education within medicine, healthcare and public health.

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