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Mattias Ekstedt

Deputy Head of Department, Senior Associate Professor

My research aims to improve the quality of life for patients through innovative treatments and diagnostic techniques. Through my teaching, I seek to spread knowledge about chronic liver diseases and convey what makes the medical profession exciting.

About me

CV

  • 2003 Medical Degree
  • 2008 Doctoral Degree
  • 2010-2015 LiÖ Research Assistant (Fo-Ass)
  • 2011 Specialist, Internal Medicine
  • 2013 STINT-Scholarship “Excellence in Teaching”, New York University, USA
  • 2013-2019 Medical Doctor (Specialistläkare), Gastroenterology and Hepatology
  • 2015-2021 Senior Lecturer (Kombinationsanställning), HMV
  • 2019- Main/Co-Supervisor for > 15 PhD students
  • 2019- Senior Consultant (Överläkare), Stomach and Intestine Department
  • 2020 Associate Professor (Docent), Gastroenterology and Hepatology
  • 2021- Senior Associate Professor, HMV

Teaching assignments

Medical Programme, LiU

  • Academic Group Supervisor
  • Course Manager K6
  • Member and former Chair, GNM Theme Group
  • Lecturer, Seminar Leader
  • Developed MEQ exams, OSCE, and oral/practical exams
  • Main Supervisor for Advanced Projects

Nursing Programme, LiU

  • Examiner, IMO3

Networks

  • Founder and Member, The Study Group for Ectopic Fat Storage
  • Member, SWEHEP
  • Board Member, Mag-Tarmfonden
  • Steering Committee Member SweLiv
  • Former National Lead for Sweden in LITMUS
  • Member, EASL International Liver Foundation NAFLD Policy Review Study Group
  • Center for Medical Image Science and Visualization, CMIV

Awards

News

Mattias Ekstedt, Nils Dahlström, Peter Lundberg, Bengt Norén and Patrik Nasr.

Adverse muscle composition linked to risk in fatty liver disease

Obesity and a sedentary lifestyle contribute to an increasing number of people developing fatty liver disease. According to a new study, poor muscle health may be a marker of risk for developing sequelae.
Mattias Ekstedt, Nils Dahlström, Peter Lundberg, Bengt Norén and Patrik Nasr.

Liver examinations without needles

How is your liver doing? Decades of research into the use of magnet resonance imaging is now being put to work to gain information about patients’ livers – without needles.
A jogger with bad condition is getting behind the other joggers.

Poor fitness and obesity linked to later chronic disease

Obesity and poor fitness in adolescence are associated with receiving disability pension due to cardiovascular disease later in life, according to a study. The good news are that even a small improvement in fitness is associated with lower risk.

Publications

Cover of publication ''
Mattias Ekstedt, Lennart E Franzén, Ulrik L Mathiesen, Lars Thorelius, Marika Holmqvist, Göran Bodemar, Stergios Kechagias (2006)
Long-term follow-up of patients with NAFLD and elevated liver enzymes.

Hepatology , Vol.44 , s.865-873 Continue to DOI

Cover of publication ''
Mattias Ekstedt, Hannes Hagström, Patrik Nasr, Mats Fredrikson, Per Stål, Stergios Kechagias, Rolf Hultcrantz (2015)
Fibrosis stage is the strongest predictor for disease-specific mortality in NAFLD after up to 33 years of follow-up

Hepatology , Vol.61 , s.1547-1554 Continue to DOI

Cover of publication ''
Patrik Nasr, Simone Ignatova, Stergios Kechagias, Mattias Ekstedt (2018)
Natural history of nonalcoholic fatty liver disease: A prospective follow-up study with serial biopsies.

Hepatology communications , Vol.2 , s.199-210 Continue to DOI

2025

Julia Blomdahl, Mikael Aberg, Michael Friden, Hakan Ahlstrom, Paul Hockings, Johannes Hulthe, Niclas Eriksson, Katja Gabrysch, Patrik Nasr, Ulf Riserus, Stergios Kechagias, Fredrik Rorsman, Mattias Ekstedt, Johan Vessby (2025) Proteomic signatures for fibrosis in MASLD: a biopsy-proven dual-cohort study Scandinavian Journal of Gastroenterology (Article in journal) Continue to DOI
Cecilia Jönsson, Showgy Ma'ayeh, Boxi Zhang, Stergios Kechagias, Mathias Liljeblad, Patrik Nasr, Sara F. Hansson, Mattias Ekstedt (2025) Vascular endothelial growth factor A, a potential non-invasive biomarker for metabolic dysfunction-associated steatotic liver disease progression Clinical Biochemistry, Vol. 137, Article 110920 (Article in journal) Continue to DOI
Jonas Agholme, Kim Ahtola, Ebba Toll, Carljohan Carlhäll, Pontus Henriksson, Stergios Kechagias, Peter Lundberg, Patrik Nasr, Oleg Sysoev, Magnus Wijkman, Mattias Ekstedt, Martin Ulander, Fredrik Iredahl (2025) Clinically available predictors of obstructive sleep apnoea requiring treatment in type 2 diabetes patients in primary care Scientific Reports, Vol. 15, Article 8710 (Article in journal) Continue to DOI
Nanicha Siriwong, Supachaya Sriphoosanaphan, Pakanat Decharatanachart, Tanat Yongpisarn, Stephen Kerr, Sombat Treeprasertsuk, Thodsawit Tiyarattanachai, Terapap Apiparakoon, Hannes Hagstroem, Camilla Akbari, Mattias Ekstedt, Terry Yip, Grace Wong, Takanori Ito, Masatoshi Ishigami, Hidenori Toyoda, Noam Peleg, Amir Shlomai, Yuya Seko, Yoshio Sumida, Miwa Kawanaka, Keisuke Hino, Roongruedee Chaiteerakij (2025) Role of noninvasive tests on the prediction of hepatocellular carcinoma in nonalcoholic fatty liver disease patients without cirrhosis: a systematic review and meta-analysis of aggregate and individual patient data European Journal of Gastroenterology and Hepathology, Vol. 37, p. 358-369 (Article in journal) Continue to DOI
Yasaman Vali, Anne-Marieke van Dijk, Jenny Lee, Jerome Boursier, Vlad Ratziu, Carla Yunis, Joern M. Schattenberg, Luca Valenti, Manuel Romero Gomez, Detlef Schuppan, Salvatore Petta, Mike Allison, Mark L. Hartman, Kimmo Porthan, Jean-Francois Dufour, Elisabetta Bugianesi, Amalia Gastadelli, Zoltan Derdak, Celine Fournier-Poizat, Elizabeth Shumbayawonda, Michael Kalutkiewicz, Hannele Yki-Jarvinen, Mattias Ekstedt, Andreas Geier, Aldo Trylesinski, Sven Francque, Clifford Brass, Michael Pavlides, Adriaan G. Holleboom, Max Nieuwdorp, Quentin M. Anstee, Patrick M. Bossuyt (2025) Precision in Liver Diagnosis: Varied Accuracy Across Subgroups and the Need for Variable Thresholds in Diagnosis of MASLD Liver international, Vol. 45, Article e16240 (Article in journal) Continue to DOI

Research

Photo of EPSONIP project meeting

EPSOMiP

EPSONIP explores the link between fatty liver, epicardial fat and cardiovascular disease in type 2 diabetes.

Metabolic dysfunction-associated steatotic liver disease (MASLD)

Metabolic dysfunction-associated steatotic liver disease (MASLD) previously known as non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease which has become the most common liver disease affecting adults and children.
Five man are standing in front of a big screen showing MR images.

The study group of ectopic fat storage

Vi studerar hur fettinlagring i olika organ, så som lever, muskel och hjärta, ökar risken för sjukdomsutveckling. Förhoppningen är att kartläggning kommer att hjälpa oss att identifiera de individer som löper högst risk att utveckla sjukdom.
Campus US with cherry blossom in the foreground.

SciLifeLab Linköping

SciLifeLab Linköping is both a local and a national research infrastructure, with unique technologies and expert competence accessible for academic and industrial researcher in the field of life sciences, health and data-driven life science.

Earlier projects

LITMUS - Liver Investigation: Testing Marker Utility in Steatohepatitis (2017-2022) CORDIS keyword LITMUS

Coworkers

Photo of Patrik Nasr

Patrik Nasr

Adjunct Associate Professor

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Stergios Kechagias

Professor

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Mikael Forsgren

Adjunct Associate Professor

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Olof Dahlqvist Leinhard

Associate Professor

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Jennifer Linge

Affilierad forskare

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Gunnar Cedersund

Associate Professor, Docent

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Valentin Kindesjö
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Nils Dahlström

Associate Professor, Head of Unit

Wolf Bartholomä

PhD student

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Peter Lundberg

Adjunct Professor

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Johan Kihlberg
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Carl-Johan Carlhäll

Professor

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Tino Ebbers

Professor

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Carl Fredholm
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Joakim Alfredsson

Senior Associate Professor

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Torsten Olbers

Professor

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Bijar Ghafouri

Professor, Head of Unit

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Cecilia Jönsson

Principal Research Engineer

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Christian Simonsson
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Martin Henriksson

Senior Associate Professor

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Fredrik Iredahl

Associate Professor, Docent

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Martin Ulander
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Martin Bergram
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Karin Rådholm

Senior Associate Professor

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Wile Balkhed
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Markus Holmberg
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Byron Lykiardopoulos
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Jonas Agholme

Bengt Norén

Simone Ignatova

Kim Ahtola

Organisation

Illustration of the letters HMV

Department of Health, Medicine and Caring Sciences (HMV)

The research areas at HMV include experimental basic research to clinical, social and public health research. We conduct high-quality education in the sought-after care professions.
Close up of three doctors dressed in surgical clothes. One stands with his back to the camera.

Division of Diagnostics and Specialist Medicine (DISP)

The division consists of three units (internal medicine, cardiovascular and radiological sciences) and contains seven subject areas within which research and teaching are conducted.
Five people in a laboratory.

Faculty of Medicine and Health Sciences (MEDFAK)

The Faculty of Medicine and Health Sciences conducts research and education within medicine, healthcare and public health.

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